2-ethenyl-4-Methyl-1,3-thiazole

2-Vinyl-4-methyl-1,3-thiazole, this is an organic compound. Its chemical properties are very interesting, let me explain in detail for you.
First, from the structural point of view, the thiazole ring has unique stability due to the electronic effects of nitrogen and sulfur atoms in the ring. The presence of 2-vinyl gives the compound unsaturation. Vinyl has high reactivity and can participate in many addition reactions. In case of electrophilic reagents, the π electron cloud of vinyl double bonds is vulnerable to electrophilic attack and electrophilic addition occurs, which is one of its important chemical properties.
Furthermore, although 4-methyl is relatively stable on the thiazole ring, the electron cloud density distribution of the thiazole ring is affected by the electron induction effect of methyl group, which in turn affects the reactivity and selectivity of the whole molecule.
In terms of its chemical stability, the thiazole ring is more stable than some ordinary heterocyclic compounds due to the existence of conjugated systems. However, under certain conditions, such as strong acid, strong base or high temperature environment, the thiazole ring may also undergo reactions such as ring opening.
In addition, the sulfur atom in this compound has a certain nucleophilicity and can participate in nucleophilic substitution reactions. In case of suitable electrophilic reagents, sulfur atoms can attack electrophilic centers with their lone pairs of electrons to form new chemical bonds.
In summary, the chemical properties of 2-vinyl-4-methyl-1,3-thiazole are rich, and its structural characteristics such as unsaturated vinyl, methyl and sulfur atoms on thiazole rings determine that it may have important applications in organic synthesis and other fields.

2-Vinyl-4-methyl-1,3-thiazole, the physical properties of this substance are quite unique. At room temperature, it is mostly liquid, and its appearance is often clear, like clear water and flexible oil. However, its color may be slightly yellowish, just like the faint halo when the morning light shines. It is not eye-catching but has its own unique charm.
Looking at its density, compared to water, it is slightly lighter, just like the thin thing that can float on the water, gently rippling on the water surface, like playing with the water. As for its boiling point, it is quite considerable, and it requires a higher temperature to boil it and turn it into the rising steam. This characteristic shows that the intermolecular force is relatively stable and not easy to disperse by heat.
In addition, the solubility of this substance also has characteristics. In organic solvents, such as ethanol, ether, etc., it shows good solubility and can blend with these solvents, just like water emulsion, forming a uniform whole; however, in water, its solubility is very small, just like the lotus leaf that repels water, it is difficult to dissolve with water, leaving only a few traces on the water surface.
In addition, 2-vinyl-4-methyl-1,3-thiazole also has a certain volatility, and in the air, it can slowly release its unique smell. Although it is not pungent and unpleasant, it is also unique, or it can be said to have a weak special aroma. In a specific environment, this smell may be detectable by people.
Such various physical properties constitute the unique physical appearance of 2-vinyl-4-methyl-1,3-thiazole, which makes it unique among many compounds and plays a different role in the research and application of various chemical fields.

2-Vinyl-4-methyl-1,3-thiazole, this is an organic compound. Its common use is of great significance in the field of organic synthesis.
Because of its unique structure, it is rich in vinyl and thiazole rings, so it can be used as a key intermediate for the preparation of many bioactive compounds. In the field of medicinal chemistry, it is often used to create new drugs, or to lay the foundation for the synthesis of anti-cancer and antibacterial drugs. For example, with its special structure, it can be combined with specific biological targets to exert therapeutic effects.
In the field of materials science, it also has a good performance. It can participate in the synthesis of polymers. Through polymerization, it can be introduced into the main chain or side chain of polymer materials to give new properties to the materials, such as improving the optical and electrical properties of the materials, enhancing the stability and durability of the materials. For example, the synthesis of polymer materials with special optical response is used in optoelectronic devices.
Furthermore, in the field of fine chemicals, it can also be used as a raw material for the synthesis of special fragrances and dyes. Due to the unique odor and color development characteristics of the thiazole ring structure, through reasonable chemical modification, unique fragrances and dyes can be prepared.

To prepare 2-vinyl-4-methyl-1,3-thiazole, the following methods can be used.
First, the sulfur-containing compound and the nitrogen-containing compound are used as the starting materials. Select suitable thiols or sulfides and react with reagents with nitrogen atoms, such as amines, under specific conditions. First, the thiols and allyl halides are nucleophilic substitution under the catalysis of bases to obtain allyl sulfide intermediates. Then, the intermediates are synthesized with nitrogenous feedstocks such as acetonitrile and ammonium chloride at high temperature and with the help of catalysts. In this process, after a cyclization reaction, nitrogen atoms interact with sulfur atoms and carbon chains to form a ring structure of 2-vinyl-4-methyl-1,3-thiazole.
Second, the derivatization reaction of thiazole ring is used. First take 4-methyl-1,3-thiazole as the substrate, and introduce a suitable leaving group at its 2-position, such as atomic halogen. 4-Methyl-1,3-thiazole can be reacted with a halogenated reagent, such as N-halogenated succinimide, in the presence of an appropriate solvent and initiator to achieve the preparation of 2-halogenated-4-methyl-1,3-thiazole. Subsequently, the halogenate is coupled with vinylboronic acid or vinyl Grignard reagent under the action of palladium catalyst. Through the formation of carbon-carbon bonds, vinyl is successfully introduced at the 2-position to obtain the target product 2-vinyl-4-methyl-1,3-thiazole.
Third, it can also start from the basic raw materials for the construction of thiazole rings. α-halogenated ketones, thioureas and vinylation reagents are used as starting materials. First, α-halogenated ketones and thioureas are reacted in alcohol solvents under mild heating conditions to form 2-amino-4-methyl-1,3-thiazole derivatives. After that, the derivative is added dropwise with vinylation reagents, such as vinyl magnesium halide, at low temperature, through nucleophilic substitution and subsequent elimination steps, the vinyl structure of the target molecule is constructed, and the final product is 2-vinyl-4-methyl-1,3-thiazole. All methods have their own advantages and disadvantages. In actual synthesis, the choice needs to be weighed according to various factors such as the availability of raw materials, the difficulty of reaction conditions, yield and purity requirements.

I think what you are asking is about the price range of 2-ethenyl-4-Methyl-1,3-thiazole in the market. However, the price of these chemical substances often changes for many reasons, and it is difficult to determine the exact number.
The change in its price is primarily related to the difficulty of production. If the production requires fine methods and rare materials, the price will be high; if the production is easy and the materials are often obtained, the price will be low. And the demand of this product in the market is also the key. If many industry players need it, the supply is less and the demand is more, and the price will rise; if the supply exceeds the demand, the price will trend down.
Furthermore, the amount purchased also affects the price. If the purchase volume is large, the merchant may give a discount, and the price is lower than the single purchase. And the difference in origin also makes the price different. In different places, the price varies due to differences in raw materials, labor, and transportation.
Although it is difficult for me to determine the range of the price, if you want to know the details, you can visit the city where chemical materials are traded, consult the merchant, or check the quotation in the network of relevant chemical transactions, and you can get a more accurate price range.