2 Chloromethyl 5 Fluorobenzo D Thiazole
quinoline thiophene imidazole thiazole

2-(CHLOROMETHYL)-5-FLUOROBENZO[D]THIAZOLE

    Specifications

    HS Code

    592147

    Chemical Formula C8H5ClFNOS
    Molecular Weight 217.65

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    Frequently Asked Questions

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    What are the physical properties of 2- (chloromethyl) -5-fluorobenzo [d] thiazole
    2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine is an organic compound with specific physical properties. Its properties are often crystalline solids. Due to the existence of various forces between molecules, such as van der Waals forces, hydrogen bonds, etc., the molecules are arranged in an orderly manner to form a crystalline structure.
    In terms of melting point, such compounds containing polar groups such as nitrogen and cyanyl groups have strong intermolecular forces, so the melting point is relatively high. The specific value will vary due to factors such as purity and crystal structure, and is roughly in a certain temperature range, which is of great significance for its separation, purification and identification. The purity and authenticity of the substance can be preliminarily judged by melting point determination. < Br >
    In terms of solubility, because its molecule contains polar cyanyl groups, it has relatively good solubility in polar solvents (such as water and alcohols), but poor solubility in non-polar solvents (such as alkanes). This property is conducive to its dissolution, extraction and reaction operations in different solvent systems. In organic synthesis, a suitable solvent can be selected according to the solubility characteristics to promote the smooth progress of the reaction or achieve product separation.
    In terms of stability, the cyanyl and pyrimidine ring structures give it certain chemical stability, but under certain conditions (such as strong acid, strong base, high temperature and the presence of specific catalysts), cyanyl groups may undergo hydrolysis, addition and other reactions. Pyrimidine rings may also participate in some nucleophilic substitution, cyclization and other reactions. Pay attention to environmental conditions during storage and use to avoid unnecessary chemical reactions.
    In appearance, pure 2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine is usually white or off-white crystal, but if it contains impurities, the color and appearance may change. By observing the appearance color and morphology, its purity can be preliminarily judged.
    What are the chemical properties of 2- (chloromethyl) -5-fluorobenzo [d] thiazole
    2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine, this property is particularly important and is related to the characteristics of many chemical changes.
    Its shape is mostly crystalline and often appears in specific chemical synthesis scenarios. The melting point is quite critical. Within a certain temperature range, this substance gradually melts from the solid state. The number of this temperature is a key indicator to characterize its physical properties, and is of concern to many chemical experiments and industrial processes.
    Solubility is also its significant physical property. In common organic solvents, such as ethanol and acetone, the degree of solubility varies. In ethanol, or according to a specific ratio of mutual dissolution, while in acetone, the dissolution state may be different. This characteristic is deeply affected in the separation, purification and other operations.
    At the level of chemical activity, its cyanyl functional group endows this substance with unique reactivity. Both cyanogen methyl and cyanyl groups can participate in many chemical reactions, such as nucleophilic substitution reactions. Under suitable reaction conditions, they can interact with specific nucleophilic reagents to realize molecular structure transformation and modification. In the field of organic synthesis, more complex molecular structures can be constructed, laying the foundation for the creation of new drugs, functional materials, etc.
    Furthermore, its conjugate structure also affects its chemical properties. The conjugate system makes the electron cloud distribution more delocalized, which affects the stability of molecules and the selectivity of reaction checking points. In some addition reactions, the conjugate structure guides the reaction to occur at a specific location, providing rules for synthetic design.
    The chemical properties of this compound have far-reaching significance and wide application in many fields such as organic synthetic chemistry and medicinal chemistry, and are an important cornerstone for chemical researchers to explore the unknown and create new substances.
    What are the common synthesis methods of 2- (chloromethyl) -5-fluorobenzo [d] thiazole?
    The common synthesis methods of 2-% (methoxy) -5-bromopyridine [d] pyrimidine generally include the following:
    First, the corresponding halogenated pyrimidine and pyrimidine derivatives are used as starting materials and achieved by the coupling reaction catalyzed by transition metals. In this process, transition metal catalysts such as palladium and nickel are often used with suitable ligands. Under specific reaction conditions, the halogenated atom of the halogenated pyrimidine is coupled to the active check point of the pyrimidine derivative, and then the core skeleton of the target product is constructed. For example, using 2-halo-5-bromopyridine and pyrimidine derivatives as substrates, heating the reaction in a suitable solvent in the presence of palladium catalyst and suitable ligands, and carefully adjusting the reaction temperature, time and proportion of reactants can effectively improve the yield and selectivity of the reaction.
    Second, synthesize through the construction reaction of pyrimidine rings. First prepare pyrimidine derivatives with suitable substituents, and then use this as a basis to construct pyrimidine rings through multi-step reactions. For example, using pyrimidine containing specific substituents as the starting material and the precursor containing pyrimidine ring structure fragments, under acidic or basic conditions, cyclize to form the target product. This path requires precise control of the reaction conditions, flexible adjustment of the reaction reagents and conditions according to the electronic effects and steric resistance of different substituents, in order to achieve the desired reaction effect.
    Third, the functional group conversion strategy is adopted. Compounds with similar structures are synthesized first, and then the functional groups are gradually converted to obtain 2- (methoxy) -5-bromopyridine [d] pyrimidine. For example, pyrimidine derivatives containing convertible functional groups are prepared first, and then the original functional groups are converted into methoxy and bromine atoms through substitution, oxidation, reduction, etc., so as to achieve the synthesis of the target product. This method has high requirements for the design of reaction steps and the selectivity of each step, and requires careful planning of reaction sequence and conditions to avoid side reactions.
    During the synthesis process, factors such as solvent selection, reaction temperature, catalyst dosage, and reactant ratio all have a significant impact on the reaction process and the yield and purity of the product. Repeated experiments and optimization are required to find the best synthesis path.
    In which fields is 2- (chloromethyl) -5-fluorobenzo [d] thiazole used?
    2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine is a good medicine and has wonderful uses in many fields.
    In the field of medicine, it can be used as a key intermediate in drug synthesis. Because this compound has a specific chemical structure and activity, it can participate in the construction of many drug molecules. After chemical modification and reaction, drugs with different pharmacological activities can be prepared, or used for antibacterial, which can inhibit the growth and reproduction of bacteria, adding a new path to anti-infection treatment; or used for anti-cancer, precise action on cancer cells, hindering their proliferation and spread, and contributing to overcoming cancer problems.
    In the field of materials science, 2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine can also be used. Due to its special chemical properties, it can be combined with other materials to give new properties to the material. Or enhance the stability of the material to make the material more durable in different environments; or improve the optical properties of the material, so that the material has unique optical properties such as luminescence and light absorption, which makes it useful in the manufacture of optical devices.
    Furthermore, in the field of agriculture, this compound may be used to create new pesticides. With its specific mechanism of action against pests, high-efficiency, low-toxicity and environmentally friendly pesticides have been developed, which can not only effectively control pests and diseases, ensure crop yield and quality, but also reduce the negative impact on the environment, which is in line with the needs of the current development of green agriculture. In conclusion, 2-% (cyanomethyl) -5-cyanofurano [d] pyrimidine has shown broad application prospects in the fields of medicine, materials science, agriculture, etc. With the deepening of research, it is expected to bring more breakthroughs and innovations to the development of various fields.
    What are the market prospects for 2- (chloromethyl) -5-fluorobenzo [d] thiazole?
    In today's world, the market prospect of 2- (cyanomethyl) -5-cyanopyridine [d] indazole drugs has attracted much attention. This is a class of unique compounds that are emerging in the field of medicine, and there seem to be many prospects to explore.
    Looking at the current state of the pharmaceutical market, there are various diseases and diverse patient needs. 2- (cyanomethyl) -5-cyanopyridine [d] indazole drugs may have potential advantages in the treatment of certain diseases due to their unique chemical structure. For example, in the treatment of some difficult diseases, the efficacy of traditional drugs may be limited, and such new drugs may be able to find new ways to bring new hope to patients.
    From the research and development level, many scientific research institutions and pharmaceutical companies have invested energy in this. With a rigorous attitude and exquisite skills, researchers have deeply explored its pharmacological mechanism, and strive to tap its potential. With the deepening of research, new discoveries and breakthroughs continue to be made, laying a solid foundation for its future application.
    Furthermore, market demand provides strong support for its development. With the improvement of public health awareness, the demand for efficient and safe drugs is increasing day by day. If 2- (cyanomethyl) -5-cyanopyridine [d] indazole drugs can demonstrate good efficacy and safety in clinical trials, they will definitely occupy a place in the market.
    However, the road ahead is not smooth. Drug development needs to go through many hurdles, and the rigors of clinical trials and the constraints of regulations and policies are all challenges. But overall, its market prospect is like the rising sun. Although it is shaded by clouds and fog, it will gradually shine. Over time, it may shine in the pharmaceutical market and contribute to the cause of human health.