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What are the main uses of 2-BROMO-6-FLUOROBENZOTHIAZOLE?
2-Bromo-6-fluorobenzothiazole is one of the organic compounds with important uses in many fields.
First, in the field of medicinal chemistry, this compound is often used as a key intermediate. Due to its unique chemical structure, it can undergo a series of chemical reactions to construct and modify complex molecular structures. By linking with other active groups, new drug molecules with specific pharmacological activities can be created. For some disease-related targets, through rational design and modification, potential therapeutic drugs can be developed, or have antibacterial, antiviral, antitumor and other effects, contributing to human health.
Second, in the field of materials science, 2-bromo-6-fluorobenzothiazole also has outstanding performance. It can be used to synthesize polymer materials with special properties. Its participation in polymerization can endow materials with unique electrical and optical properties. For example, the preparation of materials with photoelectric conversion properties can be used in the fields of organic Light Emitting Diode (OLED) or solar cells to improve the performance and efficiency of related devices and promote the progress of materials science and electronic technology.
Furthermore, in the field of organic synthetic chemistry, it is an extremely important synthetic block. Chemists can use various organic synthesis methods to carry out derivatization reactions according to their structural characteristics. In order to expand the structural diversity of organic compounds, provide a basis for further exploration of new organic reaction and synthesis strategies, and promote the continuous development of organic synthetic chemistry.
In conclusion, 2-bromo-6-fluorobenzothiazole plays an indispensable role in many fields such as medicine, materials and organic synthesis, and is of great significance to the innovation and development of various fields.
What are the physical properties of 2-BROMO-6-FLUOROBENZOTHIAZOLE?
2-Bromo-6-fluorobenzothiazole is an important compound in organic chemistry. It has specific physical properties and has been used in many fields.
Under normal temperature and pressure, 2-bromo-6-fluorobenzothiazole is mostly in the state of off-white to light yellow crystalline powder. This appearance feature is crucial for the identification and preliminary judgment of compounds.
When it comes to the melting point, it is between 85-89 ° C. As an important physical constant of compounds, the melting point is of great significance for the identification of their purity and the distinction between them and other substances. With this characteristic, in laboratory synthesis or industrial production, the purity of the product can be judged by means of melting point measurement.
In terms of solubility, 2-bromo-6-fluorobenzothiazole is insoluble in water, but soluble in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. This solubility characteristic is crucial in the solvent selection, product separation and purification steps of organic synthesis reactions.
In addition, the stability of 2-bromo-6-fluorobenzothiazole is also worthy of attention. Under normal conditions, it is quite stable in dry, cool and well-ventilated places. When encountering hot topics, open flames or strong oxidants, there may be a risk of chemical reactions, so pay attention to environmental conditions during storage and transportation to ensure safety.
The physical properties of 2-bromo-6-fluorobenzothiazole have far-reaching implications for its applications in organic synthesis, medicinal chemistry and materials science. Its appearance, melting point, solubility and stability provide important basis for research and practice in related fields.
What is the chemical synthesis method of 2-BROMO-6-FLUOROBENZOTHIAZOLE?
To prepare 2-bromo-6-fluorobenzothiazole, the following method can be followed.
First take 6-fluorobenzothiazole as the base material, because the hydrogen atom on the benzene ring has a certain activity, bromine atoms can be introduced. Liquid bromine is often used as the bromine source, and under suitable reaction conditions, it can be substituted with 6-fluorobenzothiazole.
To promote this reaction, a suitable catalyst is required. Such as iron powder or iron tribromide, these two can effectively catalyze the substitution of bromine and benzene ring. Taking iron powder as an example, it first reacts with bromine to form iron tribromide, which is a real catalyst that can polarize bromine molecules and make bromine more susceptible to reacting with benzene rings.
When reacting, temperature control is extremely critical. Usually it is suitable between low temperature and room temperature. If the temperature is too high, it is easy to cause the formation of polybrominated products and reduce the purity of the target product.
The solvent of the reaction system should not be underestimated. Halogenated hydrocarbon solvents such as dichloromethane and chloroform are commonly used. These solvents have good solubility to the reactants and are chemically stable, which does not interfere with the main reaction.
After the reaction is completed, the pure 2-bromo-6-fluorobenzothiazole can be obtained by suitable separation and purification methods according to the physical and chemical properties of the product and the impurity. If the boiling point of it is different from the impurity, it can be separated by distillation; or according to the difference in solubility in different solvents, it can be purified by recrystallization.
In this way, following this step and condition, the product of 2-bromo-6-fluorobenzothiazole can be obtained.
What is the price range of 2-BROMO-6-FLUOROBENZOTHIAZOLE in the market?
The price of 2-bromo-6-fluorobenzothiazole in the market is difficult to determine. The change in its price depends on many reasons.
First, the price of raw materials is essential. If the price of bromine, fluoride and benzothiazole-related raw materials required for its preparation is high, the price of this product will also increase. Changes in the production of raw materials and the situation of supply and demand all affect the price of raw materials. If the production of raw materials is reduced in the event of disasters, the supply will be less than the demand, and the price will rise.
Second, the preparation process is difficult and heavy. If the synthesis of 2-bromo-6-fluorobenzothiazole requires difficult steps, excellent technology, and many side reactions, the cost will be high, and the price will follow. Fine control of the process can reduce costs, and the price may be stable.
Furthermore, market supply and demand are the key. If many industries, such as medicine, chemical industry, etc., have strong demand for it, but limited production capacity, the price will rise. On the contrary, if demand is weak and production is high, the price will easily fall.
In addition, policies and regulations, environmental protection requirements also have an impact. Stringent environmental protection regulations may cause production enterprises to increase environmental protection inputs, and costs will rise and prices will move.
Due to the complexity and variability of the above reasons, the market price of 2-bromo-6-fluorobenzothiazole may fluctuate frequently. To know its exact price, you need to often observe the market conditions and consult the suppliers to clarify the current price. And the price range changes with market conditions, making it difficult to determine the exact number. Only by observing the market conditions can you know the approximate price.
What are 2-BROMO-6-FLUOROBENZOTHIAZOLE storage conditions?
2-Bromo-6-fluorobenzothiazole is an organic compound, and its storage conditions are crucial, which is related to the stability and quality of this compound. According to the traditional description style of "Tiangong Kaiwu", and it is for you.
This substance should be stored in a cool place, because high temperature can easily cause chemical reactions and damage its chemical structure. If it is fumigated in the heat of summer, or causes components to decompose and deteriorate, such as exposure to the hot sun, it is easy to cause its shape and quality to change. Therefore, it can be stored in a shady and cool place to ensure its stability.
Dry environment is also indispensable. Where the water vapor is dense, it is easy to cause reactions such as hydrolysis. If it is placed in a humid place, it will still leave wood in the rain, and it will gradually decay. Therefore, it is necessary to choose a dry warehouse, away from water sources and moisture, to prevent it from being damaged by water.
Furthermore, avoid open flames and strong oxidants. This substance has a certain chemical activity. In case of open flames, it may be dangerous to burn or explode; in contact with strong oxidants, it is easy to cause violent reactions and cause safety risks. In the place where it is stored, fireworks should be strictly prohibited, and it should not be stored in a room with strong oxidants.
Also pay attention to the integrity of the package. If the package is damaged, outside air and impurities are easy to invade and interfere with its chemical properties. It is like a leak in the house, and wind and rain can enter, damaging its contents. Therefore, the packaging should be checked frequently, and if there is any damage, it should be replaced immediately.
2-bromo-6-fluorobenzothiazole must be kept in accordance with the regulations of cool, dry, fire avoidance and oxidant, and packaging protection, so that its quality can be maintained for future use.