2 Aminothiazole 5 Carbadehyde
quinoline thiophene imidazole thiazole

2-Aminothiazole-5-carbadehyde

    Specifications

    HS Code

    902622

    Chemical Formula C4H4N2OS
    Molar Mass 128.15 g/mol
    Appearance Yellow - solid
    Melting Point 143 - 147 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, DMSO
    Odor Characteristic
    Pka Relevant acidic/basic groups may have pKa values for potential protonation/deprotonation
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Aminothiazole-5-carbadehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Aminothiazole-5-carbadehyde?
    2-Aminothiazole-5-formaldehyde, this is an organic compound. It has a wide range of uses and is a key intermediate in the synthesis of drugs. The preparation of many antibacterial and antiviral drugs depends on its participation. The unique structure of the thiazole ring and the amino group and aldehyde group endows the compound with a variety of biological activities, which can interact with targets in vivo, or hinder key metabolic processes of pathogens, or inhibit viral replication, achieving the effect of treating diseases.
    In the field of materials science, it is also useful. It can be used to react with specific materials with the reactivity of its aldehyde group to obtain materials with special properties, such as fluorescent materials. After ingenious design and reaction, the compound has become a key component of fluorescent materials, giving the material unique luminescent properties, which can be used in biological imaging, optical sensing and other fields to help scientists observe the microstructure and biomolecular activities in organisms, or sensitively detect specific substances.
    In organic synthetic chemistry, as an important synthetic building block. The active functional groups in its structure can trigger many chemical reactions, such as condensation reactions with amine compounds, construction of complex nitrogen-containing heterocyclic compounds, expand the structural diversity of organic compounds, and contribute to the development of organic synthetic chemistry, helping chemists create more new organic compounds and explore unknown chemical space.
    What are the physical properties of 2-Aminothiazole-5-carbadehyde?
    2-Aminothiazole-5-formaldehyde, this substance is a kind of organic compound. Its physical properties are quite characteristic, let me tell you in detail.
    Looking at its appearance, it is often white to light yellow crystalline powder with fine texture, like natural particles gathered in one place. This color state is quite common in organic compounds, just like the true color of many substances in natural creation.
    As for the melting point, it is within a specific range, which is a key indicator for identifying and considering the properties of the substance. The characteristics of its melting point, just like the unique identification of the substance, play an important role in many chemical reactions and practical applications. At a specific temperature, the state of matter changes from solid to liquid. This process involves the change of intermolecular forces and also highlights the characteristics of its internal structure.
    In terms of solubility, 2-aminothiazole-5-formaldehyde exhibits a certain solubility in some organic solvents. In some polar organic solvents, such as alcohols, it can be moderately dissolved, just like a fish entering water, and the molecules diffuse and disperse in the solvent. This solubility property lays the foundation for its application in organic synthesis and other fields. Because it can be dissolved in specific solvents, it can participate in various chemical reactions, just like an actor on stage and perform wonders in a chemical drama.
    In addition, its stability is also a major point. Under normal conditions, 2-aminothiazole-5-formaldehyde can maintain a relatively stable state, and the molecular structure is not easy to be damaged. However, in case of special environments, such as high temperature, strong acid and alkali and other extreme conditions, its stability may be affected, and the molecular structure may change, triggering chemical reactions and generating new substances.
    In summary, the physical properties of 2-aminothiazole-5-formaldehyde, from the appearance of color to melting point, solubility and stability, are related to each other, and together constitute the unique physical properties of the substance, which bloom in the world of organic chemistry.
    What are 2-Aminothiazole-5-carbadehyde synthesis methods?
    The synthesis method of 2-aminothiazole-5-formaldehyde has been known for a long time and has been recorded in many ancient books. The first method is to start with a sulfur-containing compound and a nitrogen-containing reagent, and to form it through a condensation reaction. First take a suitable thiol or thioether, and a compound with nitrogen atoms, such as amines or amides, under specific reaction conditions, co-place in a reactor. Appropriate temperature and pressure are applied in the kettle, and a specific catalyst is used to catalyze it. This catalyst can be either a metal salt or an organic base, which can promote the rearrangement and combination of the chemical bonds between the two, thereby gradually forming 2-aminothiazole-5-formaldehyde precursor. Subsequent to hydrolysis, oxidation and other series of fine operations to obtain a pure target product.
    Another method is based on the construction and modification of the thiazole ring. First, the basic structure of the thiazole ring is prepared, which can be formed by reacting a carbonyl compound with a bifunctional reagent containing sulfur and nitrogen. During the reaction, the proportion of the reactants, the reaction temperature and the reaction time are precisely controlled. Then, an aldehyde group is introduced at a specific position of the thiazole ring, that is, at the 5-position. This process may require the help of special organic synthesis methods, such as the use of a specific aldehyde-based reagent, under a suitable reaction environment, so that the aldehyde group can successfully replace the corresponding group. At the same time, the amino group is introduced at the 2-position, or the nucleophilic substitution reaction occurs between the amination reagent and the activity check point on the thiazole ring, and the reaction conditions are carefully regulated so that the amino group is precisely connected to the 2-position, and finally the 2-aminothiazole-5-formaldehyde is successfully synthesized.
    2-Aminothiazole-5-carbadehyde in what areas?
    2-Aminothiazole-5-formaldehyde, this substance has a wide range of uses and has important applications in medicine, pesticides, materials and other fields.
    In the field of medicine, it can be said to be a key pharmaceutical intermediate. The structure of Geiinthiazole ring exists in many drug molecules and has unique biological activities. With 2-aminothiazole-5-formaldehyde, antibacterial drugs can be synthesized. Its structure can combine with specific bacterial targets, interfere with the normal metabolism and growth of bacteria, and achieve antibacterial effect. It can also be used to synthesize anti-tumor drugs. After modification and modification, the drug can precisely act on tumor cells and inhibit the proliferation and spread of tumor cells.
    In the field of pesticides, 2-aminothiazole-5-formaldehyde is also an important raw material. Insecticides can be prepared, and their structural properties enable them to affect the nervous system or physiological and metabolic processes of pests, causing pest poisoning and death, and protecting crops from pests. It can also be used to synthesize fungicides, which can effectively inhibit the growth and reproduction of fungi, prevent and treat fungal diseases of crops, and improve crop yield and quality.
    In the field of materials, 2-aminothiazole-5-formaldehyde can participate in the synthesis of special functional materials. For example, in the synthesis of organic optoelectronic materials, it can endow materials with unique optical and electrical properties. The synthesized materials may have good fluorescence properties and can be applied to optoelectronic devices such as Light Emitting Diodes to improve the luminous efficiency and stability of the devices.
    What is the market outlook for 2-Aminothiazole-5-carbadehyde?
    2-Aminothiazole-5-formaldehyde is an important member of organic compounds. In today's chemical and pharmaceutical fields, its market prospect has attracted much attention.
    Looking at the chemical industry, this compound is often a key intermediate for the synthesis of other complex organic molecules. Due to the unique structure of thiazole ring and amino and aldehyde groups, it endows it with various chemical reactivity. Through a series of reactions, many chemicals with specific properties can be derived, such as new dyes, functional materials, etc. With the rapid development of materials science, the demand for special performance materials is increasing. 2-Aminothiazole-5-formaldehyde is used as a basic raw material or emerges in the synthesis of emerging materials, and the market potential is considerable.
    As for the field of medicine, its importance goes without saying. Many studies have shown that compounds containing thiazole structures often have significant biological activities, such as antibacterial, antiviral, and anti-tumor. 2-Aminothiazole-5-formaldehyde, as an important starting material for the synthesis of such compounds, provides an opportunity for the development of new specific drugs. Today, there is a strong global demand for innovative drugs, especially for the treatment of difficult diseases. Based on this compound, it may be able to develop breakthrough drugs, so it occupies a key position in the pharmaceutical R & D industry chain and has a bright market prospect.
    However, its market also faces challenges. Optimization of synthesis process and cost control are key. Some of the existing synthesis methods or procedures are cumbersome and the yield is not high, resulting in rising production costs and limiting their large-scale application. Furthermore, with the increasing pressure on environmental protection, the synthesis process needs to follow strict environmental regulations, and it is urgent to develop green synthesis routes. If such problems can be overcome, 2-aminothiazole-5-formaldehyde will surely shine in the chemical and pharmaceutical markets and usher in a broader development space.