2-aminobenzothiazole-6-carboxylic acid

2-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%B9%B6%E5%99%BB%E5%94%91-6-%E7%BE%A7%E9%85%B8%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%E6%89%80%E8%BF%B0:
2-Hydroxypyrimidine-6-carboxylic acid, which is a class of organic compounds with specific physical properties.
In terms of color state, it is often white to light yellow crystalline powder, which is conducive to identification and preliminary judgment. In the solid state, the texture is fine, and a certain luster can be seen under light irradiation.
In terms of solubility, the solubility in water is limited, slightly soluble in cold water, slightly increased in hot water. Because its molecular structure contains polar and non-polar parts, it has good solubility in organic solvents such as ethanol and acetone. It can be separated and purified by organic solvents according to the principle of similar miscibility. The melting point of
is about a specific range. It is generally accurately measured by a melting point tester. The specific melting point is a key indicator for identifying the purity and structure of the substance. If the sample contains impurities, the melting point will decrease and the melting range will become wider.
Stability is also important. It is relatively stable at room temperature and pressure, but in case of strong oxidants, strong acids, and strong alkalis, the structure may be damaged and chemical reactions occur. When storing, avoid contact with such substances. It should be placed in a dry, cool and ventilated place to prevent deterioration.
Density is also one of its physical properties. Although the value is not often mentioned, in some chemical production processes, such as material ratio and phase equilibrium calculation, accurate density data is indispensable.
The physical properties of the above 2-hydroxypyrimidine-6-carboxylic acids are of great significance in the fields of chemical synthesis, drug development, and materials science. In chemical synthesis, solubility and melting point properties are used to achieve separation, purification, and identification; in drug development, physical properties affect drug absorption, distribution, metabolism, and excretion, and are related to drug efficacy and safety; in materials science, these properties determine whether the substance can be used as a functional material component and application direction.

2-Aminopyrimidine-6-carboxylic acid is a very important organic compound with many unique chemical properties.
It is weakly acidic, and the carboxyl group in the molecule can dissociate hydrogen ions, showing acidic characteristics under specific conditions. This acidic nature enables it to neutralize with bases and generate corresponding salts.
The nucleophilic reactivity is quite high. The structure of pyrimidine pyrimidine ring is rich in nitrogen atoms with high electron cloud density, which has strong nucleophilicity. Under appropriate reaction conditions, it is easy to undergo nucleophilic substitution with electrophilic reagents, and then form new chemical bonds to form compounds with more complex structures. This property is of great significance in the field of organic synthesis. < Br >
The conjugate structure is significant. The conjugated system of the pyridyl pyrimidine ring and the carboxyl group endows the compound with unique optical properties and electron transfer properties. Due to its conjugation effect, the stability of the compound can be improved, and its spectral properties, such as ultraviolet-visible absorption spectroscopy, have a significant impact, and have great application potential in photochemistry and optoelectronic materials.
In addition, the compound can still undergo esterification reaction. Carboxyl groups can be esterified with alcohols under the action of catalysts to form corresponding ester derivatives. Such ester derivatives may have certain uses in flavors, drugs and other industries.
Due to the special structure of nitrogen-containing heterocycles and carboxyl groups, it can also participate in coordination reactions. Nitrogen atoms and carboxyl oxygen atoms can be used as coordination atoms to form complexes with metal ions, which may exhibit unique properties in catalysis and materials science.

The common synthesis methods of 2-% aminopyrimidine-6-carboxylic acids have attracted much attention in the field of organic synthesis. The synthesis methods generally include the following.
First, a compound containing pyrimidine and pyrimidine structures is used as the starting material, and a carboxyl functional group is introduced through appropriate reaction conditions. For example, a suitable pyrimidine derivative can be selected first, and in the presence of a specific reagent and catalyst, it can be carboxylated with a reagent that can provide carboxyl groups, such as carbon dioxide, under high temperature and high pressure conditions. In this process, precise control of reaction conditions is extremely critical, such as temperature, pressure, and catalyst dosage, which all have a significant impact on the yield and selectivity of the reaction.
Second, the carboxyl group is introduced by constructing the pyrimidine ring at the same time. A multi-step reaction can be used to gradually build the skeleton of the target molecule with common small organic molecules as the starting materials. For example, the pyrimidine ring is constructed by condensation and cyclization of simple compounds containing nitrogen and carbon. In this process, the reaction steps are cleverly designed to allow the carboxyl groups to be introduced at the same time. This method requires careful design of the reaction route, consideration of the feasibility and sequence of each step of the reaction, to ensure the smooth progress of the synthesis.
Third, the reaction strategy of transition metal catalysis is adopted. Transition metal catalysts can effectively promote the formation and cleavage of various chemical bonds, and can play an important role in the synthesis of 2-% aminopyrimidine-6-carboxylic acids. For example, transition metals such as palladium and copper are used as catalysts to catalyze the coupling reaction of halogenated pyrimidine derivatives with carboxyl-containing nucleophiles to achieve the synthesis of the target product. The advantage of this method is that the reaction conditions are relatively mild and the selectivity is high, but the selection of catalysts and the optimization of the reaction system are quite high.
Common methods for synthesizing 2-% aminopyrimidine-6-carboxylic acids have their own characteristics and scope of application. In practical applications, it is necessary to carefully select the appropriate synthesis method according to many factors such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the target product, in order to achieve the goal of efficient and high-purity synthesis.

2-% hydroxyquinolinopyridine-6-carboxylic acid has a wide range of applications and is useful in many fields.
In the field of medicine, this compound has unique biological activity. Its structural properties enable it to interact with specific targets in organisms, or it can be developed as a drug for the treatment of specific diseases. In terms of antibacterial, it can inhibit the growth and reproduction of bacteria by interfering with the key metabolic processes of bacteria or destroying the cell wall and cell membrane structure of bacteria, and may have unique effects on some drug-resistant bacteria. In terms of anti-tumor, studies have found that it may affect the signaling pathways related to tumor cell proliferation and apoptosis, and induce tumor cell apoptosis, providing new ideas for the development of anti-cancer drugs.
In the field of materials science, 2-hydroxyquinoline-pyridine-6-carboxylic acid can be used as an excellent ligand. After coordinating with metal ions, metal complexes are formed, showing special optical and electrical properties. If used to prepare luminescent materials, the complexes can emit specific wavelengths of light under specific conditions, and have potential applications in display technologies such as organic Light Emitting Diode (OLED), which can improve the display color purity and brightness. And its complexes have excellent stability and can be used to prepare high-performance sensor materials with high selectivity for specific substances, such as detecting heavy metal ions in the environment, and achieving rapid and sensitive detection of heavy metal ions through color changes or fluorescence signal changes. < Br >
In the field of analytical chemistry, the carboxylic acid can be used as an analytical reagent. With the characteristics of forming stable complexes with metal ions, the content of metal ions in the solution is determined by coordination titration, which is easy to operate and has high accuracy. It can also be used as a color developer. In spectrophotometry, it reacts with specific metal ions to form a colored complex. By measuring absorbance, quantitative analysis of metal ions can be realized. It is widely used in water quality monitoring, ore analysis and other fields.

In today's world, the trade routes are complicated, and the price changes from time to time. As for the market price of 2-aminopyrimidine-6-carboxylic acid, it is difficult to sum it up.
The determination of its price depends on various factors. First, the situation of supply and demand is necessary. If there are many people in the market who want it, but the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. Second, the cost of production is also heavy. From the collection of materials to the finished goods, the consumption of human, material and financial resources during this period is all included in the cost. If the material source is scarce, the price is high and rare, or the system is complicated and expensive, the cost will increase greatly, and the price will also be high. Third, the changes in the current situation and the regulations of the government will also have a great impact. If the production area encounters a disaster, the material source is damaged, or the government issues a decree and the restrictions are increased, the price can fluctuate.
In the past, the market situation is not stable, and the price often changes. Or due to new technologies, the efficiency of the system has increased greatly, the supply has risen sharply, and the price has dropped; or due to the surge in demand in the fields of medicine and chemical industry, the price has risen.
To know the real-time price, businesspeople often need to widely observe the market news, visit various producers and vendors, gather the feelings of all parties, and synthesize and break. It is also necessary to observe the movement of the industry, measure the future demand, and seek the profit of the business path with the direction of the price. In short, the market price of this product varies from time to time, place to place, and situation to situation. Only by careful inspection can we obtain a rough estimate.