2-Amino-6-(trifluoromethylsufanyl)benzothiazole

2-Amino-6- (trifluoromethylthio) benzothiazole is a special organic compound. Its main application field is quite wide, and it is an important synthesis intermediate in the field of medicinal chemistry. Many biologically active drug molecules are constructed, and this compound often relies on this compound to participate in the reaction. Due to its unique structure, specific functional groups can be introduced, which in turn endows the target drug molecule with unique pharmacological activities, such as the realization of antibacterial, antiviral, and anti-tumor effects.
In the field of pesticide chemistry, it also has key applications. Using it as a raw material, a variety of high-efficiency pesticides can be synthesized. Such pesticides may have significant inhibitory or killing effects on specific pests and pathogens, and may have higher selectivity and environmental friendliness than traditional pesticides. They can ensure crop yield and quality while minimizing the negative impact on the environment.
Furthermore, in the field of materials science, 2-amino-6- (trifluoromethanthio) benzothiazole can also be used. Through appropriate chemical reactions, it can be introduced into polymer materials to improve the properties of materials. It can improve the stability and corrosion resistance of materials, or endow materials with special optical and electrical properties, opening up new paths for the research and development of new functional materials.
Overall, 2-amino-6- (trifluoromethanethionyl) benzothiazole plays an indispensable role in many important fields such as medicine, pesticides, materials, etc., and is of vital significance to promote the development of related fields.

The synthesis method of 2-amino-6- (trifluoromethylthio) benzothiazole has been known for a long time, and there are many paths. The following is your detailed introduction.
First, you can start from sulfur-containing compounds and nitrogen-containing compounds. If you take a suitable thiophenol derivative, react it with a nitrogen-containing heterocyclic precursor. First, the thiophenol derivative and a suitable halogenated hydrocarbon under basic conditions, with the help of a phase transfer catalyst, perform a nucleophilic substitution reaction to obtain a sulfur-containing intermediate product. This reaction requires precise temperature control, generally between ice baths and room temperature, and the duration is about several hours (2-4 hours). Then, the intermediate product and the nitrogen-containing heterocyclic precursor are heated and refluxed in a high-boiling organic solvent with a specific metal salt as a catalyst. After several hours (3-6 hours), the target product 2-amino-6- (trifluoromethylthio) benzothiazole can be obtained. The key to this path lies in the precise control of the reaction conditions at each step, such as temperature, pH and catalyst dosage.
Second, benzothiazole parent is used as the starting material. The amination reaction of benzothiazole is carried out first. Usually, ammonia or ammonia derivatives are used as the amino source. In the presence of a specific reaction medium and catalyst, the reaction is heated, and the amino-substituted benzothiazole is obtained after several hours (4-8 hours). Subsequently, trifluoromethylthio is introduced. Generally, trifluoromethylsulfur halide is used as a reagent. Under the action of alkali, it reacts with amino-substituted benzothiazole. The reaction temperature is between room temperature and moderate heating (30-60 ° C), and it lasts for several hours (2-5 hours) to obtain the target molecule. This approach focuses on the balance of reaction activities in each step to avoid overreaction or side reactions.
Third, it is synthesized by one-pot method. A variety of starting materials, including reagents containing sulfur, nitrogen and trifluoromethyl sulfur groups, are placed in the same reactor in a certain proportion, and suitable composite catalysts and reaction solvents are added. By gradually changing the reaction conditions, such as temperature, pH, etc., the reaction proceeds in sequence without separating the intermediate products, and 2-amino-6- (trifluoromethylthio) benzothiazole is directly obtained. Although this method is convenient, it requires extremely high optimization of the reaction conditions. It is necessary to carefully explore the optimal combination of the proportion of raw materials, catalyst dosage, reaction temperature and time to improve the yield and purity.

2-Amino-6- (trifluoromethylthio) benzothiazole, this product has specific properties and is worth exploring. It is a white to light yellow crystalline powder with a pure and delicate appearance. It has good stability at room temperature and can exist stably in general environments. It rarely mutates spontaneously.
The melting point is about 170-175 ° C. When the temperature gradually rises to the melting point, the product slowly melts from solid to liquid, and the process is smooth and orderly. The exact value of the melting point is a key indicator for quality inspection and purity determination in the fields of chemicals and pharmaceuticals.
Its solubility is also characteristic. In organic solvents such as dichloromethane, N, N-dimethylformamide, it can be moderately dissolved, but in water it has little solubility. This difference in solubility has a significant impact on the separation, purification and preparation of compounds.
From the perspective of chemical activity, the presence of amino groups and benzothiazole rings in the molecular structure makes it exhibit a certain alkalinity. It can quietly react with acids to form corresponding salts. The introduction of trifluoromethyl thio groups greatly enhances its lipophilicity and electronic effects, which not only affects the physical properties of compounds, but also plays a key role in many chemical reactions, affecting the reaction path and product composition.
Due to its unique physical and chemical properties, 2-amino-6- (trifluoromethylthio) benzothiazole has great potential in the field of pharmaceutical research and development, or can become a key intermediate for the creation of new antibacterial and antiviral drugs; in the field of materials science, it is also expected to participate in the development of new functional materials with its special structure and properties.

In today's world, it is not easy to know the market price range of 2 - Amino - 6 - (trifluoromethylsufanyl) benzothiazole. This product may be a fine chemical, and its price fluctuations are often tied to multiple factors.
First, the cost of raw materials has a significant impact. If the price of various raw materials required for the synthesis of this compound rises due to scarcity of supply, changes in origin or market supply and demand imbalances, the cost of 2 - Amino - 6 - (trifluoromethylsufanyl) benzothiazole also rises, which in turn increases its market price.
Second, the difficulty of the preparation process is closely related to the cost. If the synthesis of this substance requires complex and high-cost technologies, such as special reaction conditions, expensive catalysts or cumbersome reaction processes, the price will also rise accordingly.
Third, the market supply and demand relationship is also the key. If there is a strong demand for this substance in many industries, such as pharmaceutical research and development, material science and other fields, and the supply is relatively limited, the price will rise; conversely, if the demand is low and the supply is excessive, the price may drop.
Fourth, different suppliers will set different prices due to differences in their own scale, production efficiency, operating costs, etc. Large and efficient suppliers may offer relatively low prices due to economies of scale, while small suppliers may offer relatively high prices due to cost constraints.
However, it is difficult to find the exact price range by searching past transaction records and market conditions. Or because the application of the compound is relatively small, market data is less disclosed; or because the transaction is mostly carried out privately through specific channels, it is not widely known. Therefore, in order to obtain an accurate price range, it is necessary to consult professional chemical product trading platforms, relevant industry practitioners or suppliers in detail to know a thing or two.

2-Amino-6- (trifluoromethylthio) benzothiazole is a key intermediate in the field of chemical synthesis, and is widely used in various industries such as medicine, pesticides, and materials. However, after searching through the past books, I cannot know exactly what the manufacturer of this product is.
At present, the chemical industry is booming, and the manufacturers are scattered all over the world. Or there are many large chemical companies with advanced technology and equipment, skilled in organic synthesis, and also specialized in the production of characteristic intermediates.
If you want to know the name of the manufacturer, you can explore it from many sources. First, the chemical industry classics, professional magazines, often contain the enterprise's dynamic and product information, or can be gained; Second, with the help of the Internet, many chemical products trading platforms, industry forums, people may be able to share information about relevant manufacturers; Third, participate in chemical industry exhibitions, seminars and other activities, where you can face each manufacturer and inquire about product details.
Although I can't list the names of the manufacturers one by one, according to the above method, we may be able to find the required information to meet the needs of 2-amino-6- (trifluoromethylthio) benzothiazole.