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What are the main uses of 2-Amino-6-cyanobenzothiazole?
2-Amino-6-cyanobenzothiazole is one of the organic compounds with a wide range of uses. In the field of medicine, it is often used as a key intermediate in drug synthesis. Due to the unique structure of benzothiazole, it is endowed with a variety of biological activities. Based on this, many drugs with specific pharmacological effects can be created, such as antibacterial, antiviral, anti-tumor and other drugs.
In the field of pesticides, it also has important applications. With its chemical properties, efficient and low-toxic pesticides can be developed, or with insecticidal, bactericidal, and herbicidal effects, which can help agricultural pest control and crop yield increase.
In the field of materials science, 2-amino-6-cyanobenzothiazole can participate in the preparation of special materials. Its structure can endow materials with unique electrical, optical or mechanical properties, such as in optoelectronic materials, or can optimize the photoelectric conversion efficiency of materials and other properties, promoting the development of related materials.
In addition, in the dye industry, it may provide a key structural unit for the synthesis of new dyes, making the dyes show unique color, stability and dyeing properties to meet the needs of different fields. In short, 2-amino-6-cyanobenzothiazole plays an indispensable role in many fields and has a profound impact on the development of related industries.
What are the physical properties of 2-Amino-6-cyanobenzothiazole?
2-Amino-6-cyanobenzothiazole is an organic compound. It has unique physical properties, so let me tell you one by one.
Under normal temperature and pressure, it is mostly in a solid state, which is caused by strong intermolecular forces. Its appearance is often white to light yellow powder, with pure color and uniform quality. This appearance feature helps to identify and distinguish initially.
When it comes to melting point, it is about 196-199 ° C. The melting point is an important property of the substance. This temperature range indicates that a specific energy is required to break the orderly arrangement of the molecular structure. This value can be used for purity identification. If the purity is high, the melting point range is narrow and approaches the standard value; if it contains impurities, the melting point is reduced and the range is widened.
Its solubility also has characteristics. It is slightly soluble in water, because although there are polar groups in the molecule, the benzothiazole ring has strong hydrophobicity with cyanide, weak interaction with water molecules, and it is difficult to disperse in water. However, it can be soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc. This is because the organic solvent and the compound can form hydrogen bonds or van der Waals forces to promote dissolution. This solubility provides a basis for the selection of solvents for reaction substrates or active ingredients in organic synthesis and drug development.
To discuss its stability. Under normal conditions, 2-amino-6-cyanobenzothiazole is relatively stable. However, its amino group and cyano group are highly active, and when exposed to strong acids, strong bases or strong oxidants, chemical reactions can occur to cause structural changes. For example, in strong acids, amino groups are easily protonated; in case of strong oxidants, cyano groups may be oxidized to carboxyl groups, etc. When storing and using, this chemical environment sensitivity should be considered, and it should be properly stored to prevent deterioration.
2-Amino-6-cyanobenzothiazole has unique physical properties and is widely used in organic synthesis and medicinal chemistry. Understanding its properties is of great significance to related research and production.
2-Amino-6-cyanobenzothiazole chemical synthesis methods
The synthesis method of 2-amino-6-cyanobenzothiazole has been known in ancient times, and there are various ways. First, it can be obtained from the condensation reaction of o-aminothiophenol and cyanoacetamide as raw materials. In this process, the sulfur atom of o-aminothiophenol and the carbonyl group of cyanoacetamide undergo nucleophilic addition, followed by cyclization and dehydration, and finally form the target product. During the reaction, it is necessary to pay attention to the control of the reaction temperature and time. If the temperature is too high or the side reaction occurs, if the time is too short, the product yield will not reach its extreme.
Furthermore, the nucleophilic substitution reaction with 2-halo benzothiazole and cyanide reagent as the starting material can also be prepared. In this path, the activity of the halogen atom is related to the reaction process, and the higher the activity of the halogen atom, the easier the reaction will be. However, the cyanide reagent is toxic, and when operating, safety procedures should be strictly followed to prevent harm.
There are also those who use 2-aminobenzothiazole as a substrate and obtain 2-amino-6-cyanobenzothiazole through cyanylation. During the cyanylation process, the cyanide agent and catalyst selected have a great impact on the reaction. The combination of different cyanide agents and catalysts can cause very different reaction activity and selectivity.
All these synthesis methods have their own advantages and disadvantages. In practical application, when the most suitable method is carefully selected according to factors such as the availability of raw materials, cost considerations, and product purity requirements, it can achieve twice the result with half the effort, so as to smoothly achieve the synthesis of 2-amino-6-cyanobenzothiazole.
What is the price range of 2-Amino-6-cyanobenzothiazole in the market?
It is difficult to determine the price of 2-amino-6-cyanobenzothiazole in the market. The price of this product often changes for various reasons. First, the price of raw materials moves. If the price of the raw material for making this product fluctuates, the price of 2-amino-6-cyanobenzothiazole will also change accordingly. Second, the trend of supply and demand. If there are many people in the market who want this product, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price may fall. Third, the precision of the craftsmanship, the distance of the origin, and the calculations of the merchants are all related to its price.
Looking at past market conditions, the price of 2-amino-6-cyanobenzothiazole is between tens and hundreds of yuan per kilogram. However, this is only an approximate number and cannot be specified. In today's market, if you want to know the true price, you should consult various chemical merchants or visit relevant trading platforms to get near-real price information. Cover the ever-changing market conditions, real-time prices can only be expressed in recent times.
What are 2-Amino-6-cyanobenzothiazole manufacturers?
2-Amino-6-cyanobenzothiazole is an important organic synthesis intermediate, which is widely used in the fields of medicine, pesticides, dyes and other fields. Looking for its manufacturer is like exploring the pearl hidden in the business sea, which needs to be carefully identified.
In the land of Huaxia, many chemical companies are involved in the production of this product. For example, some manufacturers in Shandong have profound chemical industry heritage. With advanced production technology and strict quality control, they have emerged in the field of 2-amino-6-cyanobenzothiazole production. They pay attention to technological innovation and continuously optimize production processes to improve product quality and production capacity.
There are also enterprises in Zhejiang focusing on this field. With its flexible market strategy and efficient operation model, it occupies a place in the competition. It is good at capturing changes in market demand and adjusting production plans in a timely manner. The 2-amino-6-cyanobenzothiazole produced is very popular in the industry.
In addition, there are also relevant manufacturers in Jiangsu and other places. They either rely on their unique technical advantages or rely on a complete industrial chain to provide a stable product supply to the market.
However, it should be noted that the production of chemical products is related to safety and environmental protection. All manufacturers should follow relevant regulations and policies to ensure that the production process is green and safe. Purchasers should also carefully examine the manufacturer's qualifications, reputation and product quality in order to reach satisfactory cooperation and jointly promote the steady development of the 2-amino-6-cyanobenzothiazole industry.