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What are the main uses of 2-Amino-5-nitrothiazole?
2-Amino-5-nitrothiazole is an important category of organic compounds. It has a wide range of uses and is often a key intermediate for the synthesis of antibacterial and anti-parasitic drugs in the field of medicine. The special structure of Geiinthiazole ring and amino and nitro groups endows the compound with unique biological activity, which can effectively act on specific targets of microorganisms and inhibit their growth and reproduction.
In terms of pesticides, it is also a raw material for the synthesis of new pesticides. It can develop high-efficiency and low-toxicity pesticide products against various pests and pathogens, which can help agricultural pest control and improve crop yield and quality. Due to its structural stability and biological activity, it can precisely act on pests and reduce the impact on the environment and non-target organisms.
In addition, in the field of materials science, 2-amino-5-nitrothiazole has also emerged. It can be used to prepare functional materials with special properties, such as smart materials with the ability to recognize and respond to specific substances. Due to the characteristics of groups in its molecular structure, it can interact with other substances to achieve precise regulation of material properties. Therefore, 2-amino-5-nitrothiazole has important application value in many fields and is an indispensable ingredient for modern chemical industry and related scientific research.
What are the physical properties of 2-Amino-5-nitrothiazole?
2-Amino-5-nitrothiazole is an important organic compound with many unique physical properties. This substance is mostly in the form of light yellow to light brown crystalline powder at room temperature, and it looks delicate, just like the purity of the first snow in winter. Its melting point is in a specific range, about 198-202 ° C. When heated up to this point, it is like ice melting in spring, gradually turning from solid to liquid.
2-amino-5-nitrothiazole has low solubility in water, just like sinking into the sea, and is difficult to melt with water. However, in some organic solvents, such as dimethylformamide, dimethyl sulfoxide, etc., it can dissolve to a certain extent, just like a wanderer finding a suitable place to live. This solubility property is of great significance for its application in chemical synthesis and related fields.
Furthermore, its density is also a key physical property. The specific value varies with accurate measurement conditions, but it is roughly within a specific range, giving it a specific relationship between mass and volume in the material system, which needs to be considered in many practical operations. Its stability is acceptable at room temperature and pressure, but in case of extreme conditions such as high temperature and strong oxidizing agents, the structure may change, and in case of dry firewood from fire, it will trigger corresponding chemical reactions. The physical properties of this compound lay the foundation for its application in chemical industry, medicine and other fields, and help researchers to seek advantages and avoid disadvantages in related explorations and use it rationally.
What is the chemical synthesis method of 2-Amino-5-nitrothiazole?
2-Amino-5-nitrothiazole is also an organic compound. The method of chemical synthesis has undergone many ingenious efforts.
In the past, the synthesis method was based on thiazole and obtained by multi-step modification. At first, suitable sulfur and nitrogen-containing raw materials, such as thiourea and halogenated carbonyl compounds, were taken to combine the two to form the prototype of thiazole. During the reaction, it is necessary to control the temperature, control the time, and choose the appropriate solvent and catalyst to make the reaction smooth.
Then, the prototype of thiazole was modified. To introduce nitro groups, a mixed acid of concentrated nitric acid and concentrated sulfuric acid is often used as a nitrifier. However, this process is quite risky and requires caution. Because the mixed acid is highly corrosive and oxidizing, a little carelessness can cause an accident. During nitrification, the temperature should be precisely adjusted to keep the reaction within a controlled range to prevent excessive nitrification or other side reactions.
After the nitro is introduced, the amino group is introduced. This step is not easy, and suitable amination reagents, such as ammonia derivatives, are required. At the same time, consider the influence of existing groups in the molecule to avoid unnecessary side reactions.
There are other methods to synthesize from different starting materials through unique reaction paths. Or first prepare thiazole derivatives containing specific substituents, and then introduce nitro and amino groups in sequence. The control of reaction conditions and the connection of each step of the reaction are all related to the success or failure of the synthesis.
In short, the synthesis of 2-amino-5-nitrothiazole requires fine study of the reaction mechanism and good control of conditions in order to obtain pure products. In the field of organic synthesis, it is an important exploration and practice.
What is the price range of 2-Amino-5-nitrothiazole in the market?
2-Amino-5-nitrothiazole is in the market, and its price range is difficult to determine with certainty. The price of this chemical often changes due to multiple reasons. First, the production sources are different, and the price may vary. If the production is wide and easy, the price may be cheap; if the production is rare and difficult, the price must be high. Second, the supply and demand of the city is also due to the. If there are many people in need and few people in supply, the price will rise; if there are few people in need and many people in supply, the price will drop. Third, the quality of the quality also involves the price. The price of the superior is high, and the price of the second is low.
Looking at past market conditions, the price of 2-amino-5-nitrothiazole varies from tens to hundreds of gold per kilogram. At some point, the price may fall to thirty or forty gold per kilogram due to abundant production; at other times, or due to urgent need and shortage, the price may rise to two or three hundred gold per kilogram. However, this is only a rough figure, and the actual price varies with the changes in the market. Therefore, if you want to know the exact price, you should consult the merchants in the market, or observe the real market conditions.
What are 2-Amino-5-nitrothiazole manufacturers?
2-Amino-5-nitrothiazole is an important intermediate in organic synthesis, which is widely used in the fields of medicine, pesticides and dyes. However, its manufacturers are distributed all over the country, and it is difficult to describe them. Only a few examples can be cited to illustrate.
There is a Shanghai search banner biochemical technology joint stock company in China. This company focuses on the research and development, production and sales of biochemical reagents. Its product categories are rich, and 2-amino-5-nitrothiazole is also among them. It has high quality and stable supply, and is widely recognized in the industry.
Another Jiangsu Yonghua Fine Chemicals Co., Ltd. has considerable strength in the field of fine chemical manufacturing. The company has excellent technology and scientific management. The quality of 2-amino-5-nitrothiazole produced is quite good. It is sold in many places in China and some are exported, and it has a place in the market.
Foreign companies such as Sigma-Aldrich are world-renowned chemical suppliers, famous for their complete range of products and excellent quality. Its 2-amino-5-nitrothiazole products meet international high standards and are favored by many scientific research institutions and enterprises around the world.
However, to find a suitable manufacturer, many factors need to be considered. Such as product quality, when it meets the corresponding standards and requirements to meet different uses; supply capacity cannot be ignored, it is necessary to ensure stable supply and respond to market demand; furthermore, the price factor is also the key, and a balance must be found between quality and cost. In addition, the reputation and service level of the manufacturer are all essential when purchasing.