2 Amino 5 Formyl 1 3 Thiazole
quinoline thiophene imidazole thiazole

2-Amino-5-formyl-1,3-thiazole

    Specifications

    HS Code

    368685

    Name 2 - Amino - 5 - formyl - 1,3 - thiazole
    Molecular Formula C4H4N2OS
    Molecular Weight 128.15 g/mol
    Appearance Solid (usually a white to off - white powder)
    Melting Point Typically in the range of 180 - 185 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in polar organic solvents like ethanol, DMSO
    Odor Mild, characteristic odor
    Stability Stable under normal conditions, but sensitive to strong acids and bases

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    General Information
    Where to Buy 2-Amino-5-formyl-1,3-thiazole in China?
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    Frequently Asked Questions

    As a leading 2-Amino-5-formyl-1,3-thiazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-Amino-5-formyl-1,3-thiazole?
    2-Amino-5-formyl-1,3-thiazole, which is a heterocyclic organic compound containing nitrogen and sulfur. Its chemical properties are unique and have a variety of reactivity.
    Looking at its structure, the amino group and formyl group are connected to the thiazole ring, which endows the compound with various chemical properties. The amino group is basic and can react with acids to form salts, and can participate in nucleophilic substitution reactions. It interacts with electrophilic reagents such as halogenated hydrocarbons to form new nitrogen-containing derivatives, which are often used in organic synthesis to construct nitrogen-containing carbon-nitrogen bonds.
    formyl group has strong electrophilicity and can undergo a variety of reactions. It can participate in the condensation reaction of hydroxyaldehyde, and form α, β-unsaturated aldehyde and ketone compounds under alkali catalysis, providing important intermediates for organic synthesis. At the same time, formyl groups can be reduced, such as sodium borohydride and other reducing agents, which can be reduced to hydroxymethyl groups, enriching the functional groups of compounds.
    Thiazole ring itself is also stable and reactive. Because of its conjugate structure, it can participate in electron transfer related reactions. In addition, 2-amino-5-formyl-1,3-thiazole may have certain biological activity, and can be used as a lead compound in the field of medicinal chemistry to develop new drugs through structural modification.
    In summary, 2-amino-5-formyl-1,3-thiazoline has a special structure and rich chemical properties, and may have broad application prospects in many fields such as organic synthesis and drug development.
    What are the main uses of 2-Amino-5-formyl-1,3-thiazole?
    2-Amino-5-formyl-1,3-thiazole, this is an organic compound that has important uses in many fields.
    In the field of medicinal chemistry, it can be used as a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, or exhibit pharmacological activities such as antibacterial, anti-inflammatory, and anti-tumor. Doctors and pharmacists know that the development of drugs often relies on such compounds as starting materials, which are chemically modified and modified to obtain new drugs with better efficacy and less side effects.
    In the field of materials science, 2-amino-5-formyl-1,3-thiazole can also be used. Because of its specific electronic properties and molecular configuration, it can participate in the synthesis of materials with special optical and electrical properties. For example, it can be used to prepare organic Light Emitting Diode (OLED) materials, which contribute to the development of display technology, making the screen display clearer and more colorful.
    Furthermore, in the field of agricultural chemistry, the compound may be used to develop new pesticides. Its structural characteristics may give it the ability to inhibit or kill certain pests and pathogens, and it is more environmentally friendly and biodegradable than traditional pesticides. It can not only effectively protect crops, but also reduce damage to the environment. It is a beneficial contribution to the sustainable development of agriculture.
    In short, 2-amino-5-formyl-1,3-thiazole has important uses in medicine, materials, agriculture and other fields. With the continuous progress of science and technology, its potential application value may be further explored and expanded.
    What is the synthesis method of 2-Amino-5-formyl-1,3-thiazole?
    The synthesis of 2-amino-5-formyl-1,3-thiazole is a key issue in the field of organic synthesis. To prepare this substance, multiple methods can be used.
    First, sulfur-containing compounds and nitrogen-containing compounds are used as starting materials. First, appropriate thiols or thioethers are taken and reacted with halogenated alarms in a basic environment to form sulfur-containing intermediates with aldehyde groups. In this process, the selection and dosage of basic reagents are very important. Common bases such as potassium carbonate and sodium hydroxide need to be carefully determined according to the activity of the reaction substrate and the reaction conditions.
    Then, this intermediate is reacted with ammonia or amine compounds. The structure of ammonia or amine can affect the reaction rate and product purity. If ammonia is used, the reaction is relatively direct; if an amine with a specific structure is used, a unique substituent can be introduced to change the properties of the product. The reaction conditions also need to be fine-tuned, and the temperature and reaction time will affect the yield and product selectivity.
    Second, the construction strategy of thiazole ring can be borrowed. Using dicarbonyl compounds and thioureas or their derivatives as raw materials, under the catalysis of acids or bases, the thiazole ring is cyclized to form a thiazole ring. In this reaction, the type and dosage of catalyst are the key. When catalyzing acids, common acids such as hydrochloric acid and sulfuric acid, etc., are suitable for alkali catalysis, such as sodium oxide and potassium tert-butanol.
    During the reaction process, temperature control is particularly important. If it is too low, the reaction will be slow, and if it is too high, side reactions will occur. And the proportion of raw materials also needs to be precisely prepared to ensure that the thiazole ring is correctly constructed and the required amino and formyl groups are introduced.
    In addition, post-reaction treatment is also critical. It is often necessary to extract, distillate, recrystallize and other steps to purify the product, improve the purity, and obtain high-quality 2-amino-5-formyl-1,3-thiazole.
    What is the market price of 2-Amino-5-formyl-1,3-thiazole?
    It is not easy to know the market price of this product 2 - Amino - 5 - formyl - 1,3 - thiazole. Prices in the city often vary with time, place, quality, and supply and demand conditions.
    If you want to study its price, you should look at the four-sided city. Its wide and narrow production, and how much it is used, are the key. In chemical markets, or there are merchants who sell it. If it is produced in a large number, and the users are not prolific, the price is flat; if it is produced thin and used in a hurry, the price must be high.
    And the purity of this product is also related to the price. Pure, or the price is high; miscellaneous, the price or inferior. And the distance of the place also has an impact. Near the place of production, the price or the cost of freight is accumulated; where it is far away, the price or the cost of transshipment is increased.
    Furthermore, the flow of time also makes the price different. The year is rich, the season is weak and prosperous, and the price changes with the times. Therefore, if you want to know the market price of 2 - Amino - 5 - formyl - 1,3 - thiazole, you must widely observe the market conditions and study various factors to obtain its approximation.
    What are the precautions for 2-Amino-5-formyl-1,3-thiazole in storage and transportation?
    2-Amino-5-formyl-1,3-thiazole is an organic compound. During storage and transportation, many matters must be paid attention to.
    First, storage, this compound is quite sensitive to environmental factors. First, humidity is crucial. Because of its certain water absorption, if the storage environment humidity is quite high, it may cause deliquescence, which in turn affects the quality and purity. Therefore, when placed in a dry place, a desiccant can be prepared around the storage container to maintain a dry environment. Second, temperature cannot be ignored. High temperature or cause the decomposition and deterioration of the compound should be stored in a cool place. Generally speaking, the temperature is 2-8 ° C. This temperature range can effectively delay the chemical reaction that may occur and ensure its stability. Third, light may also affect it. This compound may be photosensitive, and may deteriorate after being exposed to light for a long time. It needs to be protected from light during storage. It can be placed in a brown bottle or stored in a place where light is difficult to reach.
    As for transportation, safety and security are the top priority. Due to its special chemical properties, strict regulations must be followed during transportation. The packaging must be solid and reliable to prevent the package from being damaged due to collision and vibration during transportation and cause leakage. And the transportation vehicle needs to have suitable environmental control devices to maintain relatively stable temperature and humidity. At the same time, transportation personnel should be familiar with the characteristics of this compound and emergency treatment methods. In case of emergencies such as leakage, they can respond quickly and correctly to avoid the expansion of harm.
    All of these, storage and transportation of 2-amino-5-formyl-1,3-thiazole, all need to be cautious to ensure its quality and safety.