2-AMINO-5-CHLOROBENZOTHIAZOLE

2-Amino-5-chlorobenzothiazole is an organic compound. It has a wide range of uses and has important applications in many fields.
In the field of medicine, it is often a key intermediate in the synthesis of many drugs. Due to its unique chemical structure, it can impart specific activities and properties to drug molecules. By chemical reaction, it can be integrated into the molecular structure of the drug, so that the drug can act more effectively on specific targets, thereby improving the efficacy of the drug. For example, in the development of antimicrobial drugs, 2-amino-5-chlorobenzothiazole can participate in the construction of compounds with unique antimicrobial mechanisms to help fight specific pathogenic infections.
In the dye industry, it also plays an important role. Because its chemical structure can be modified to produce a specific color and stability, it is often used to synthesize new dyes. Such dyes have the advantages of bright color and good light resistance. They are widely used in the dyeing process of textile, leather and other industries, which can make fabrics and leather show rich color and maintain color for a long time.
In the field of agriculture, it can participate in the synthesis of pesticides. With the help of rational design and reaction, pesticide ingredients with efficient control effect on crop diseases and pests are constructed. These pesticides can precisely act on pests and have a small impact on the environment, which is helpful to achieve green agricultural production and ensure crop yield and quality.
In summary, 2-amino-5-chlorobenzothiazole plays an indispensable role in the fields of medicine, dyes, and agriculture, and plays an important role in promoting the development of various industries.

2-Amino-5-chlorobenzothiazole, this material belongs to a class of organic compounds. It has a special appearance. At room temperature, it is mostly white to light yellow crystalline powder, and its appearance is delicate. Under light or shimmering light. Its smell is quite weak, but if you smell it carefully, you can still feel a special smell, just like the unique light fragrance of organic matter, but it is not pungent.
When it comes to the melting point, the melting point of this substance is quite high, about 190-195 ° C. Under high temperature, it melts into a liquid state, which is due to the compactness of its molecular structure and the strong interaction force. The boiling point is also not low, and a very high temperature is required to make it boil into a gaseous state, which reflects the attractive force between molecules and is not easily broken by heat energy.
In terms of solubility, 2-amino-5-chlorobenzothiazole has little solubility in water, because its molecular polarity is quite different from that of water, and the polarity of water is difficult to affinity with the organic molecule. However, in organic solvents such as ethanol and acetone, it has better solubility, because it is compatible with the force between the organic solvent molecules and can be evenly dispersed in it.
In terms of stability, this substance is quite stable at room temperature and pressure and protected from light and moisture, and the molecular structure is not easy to change. However, under extreme conditions such as strong acid and alkali, or high temperature and strong oxidizing agent, the molecular structure may be damaged, triggering chemical reactions and altering the original physical and chemical properties.

The synthesis methods of 2-amino-5-chlorobenzothiazole have existed in ancient times, and there are many kinds. The methods of the past are mostly based on classical organic synthesis techniques.
One method is to use anthranilic acid as the starting material. First, it is heated with ammonium thiocyanate and cyclized to form benzothiazole-2-ketone intermediates. This intermediate is treated with chlorination reagents such as phosphorus oxychloride and phosphorus pentachloride. Under suitable temperature and reaction time, 2-chlorobenzothiazole derivatives can be obtained. Subsequently, through the amination reaction, with liquid ammonia or other ammonia sources, under specific conditions, the chlorine atom at the 2-position is replaced with an amino group, and the final product is 2-amino-5-chlorobenzothiazole.
Another method is to use 2-aminothiophenol as the starting material. React it with chloroacetyl chloride to form a thioether intermediate. Then under basic conditions, such as sodium hydroxide or potassium hydroxide in an alcohol solution, heat cyclization to directly construct a benzothiazole ring. After the chlorination step, a suitable chlorination agent is selected, and a chlorine atom is introduced at the 5-position of the benzothiazole ring in a suitable reaction environment, and the target product is obtained.
Furthermore, there are also those who use 5-chloro-2-nitrobenzothiazole as raw material. Using reducing agents, such as the combination of iron filings and hydrochloric acid, or hydrogen and palladium-carbon catalyst systems, nitro groups can be reduced to amino groups, and 2-amino-5-chlorobenzothiazole can also be synthesized.
All these synthesis methods have their own advantages and disadvantages. According to actual needs, consider the availability of raw materials, the difficulty of reaction conditions, the purity of the product and many other factors, and choose the best one.

2-Amino-5-chlorobenzothiazole is on the market, and its price range is difficult to determine. The price of this product often changes for many reasons, just like the changing situation, unpredictable.
The price of its raw materials is the key end. If the raw materials are easy to obtain and the price is flat, the price of this product may stabilize and be slightly lower; however, the raw materials are rare and expensive, then the price of this product must rise.
The production method also has a great impact. A refined method may reduce its cost and make the price drop; if the production method is cumbersome and expensive, the price should be high.
The state of market supply and demand is even more leading to its price trend. There are many people in need and few people in supply, and the price is like a flying canopy; if the supply exceeds the demand, the price will be like autumn leaves.
Furthermore, differences in regions and changes in seasons also affect their prices. The land price of one party is high, and the price of the other may be low; when the price needs to rise, it needs to fall when the price is low.
Therefore, in order to know the exact price range of 2-amino-5-chlorobenzothiazole, it is necessary to carefully observe the raw materials, production methods, supply and demand, and pay attention to the changes in regions and seasons. The market situation is complex, and the number of prices is difficult to generalize.

For 2-amino-5-chlorobenzothiazole, there are several ends to be paid attention to during storage and transportation. This substance has specific chemical properties, so when stored, the first environment is dry and cool. If it is placed in a humid and warm place, or causes it to deteriorate, it will cause chemical structure changes, which will damage quality and efficiency. It is necessary to choose a well-ventilated place to avoid the accumulation of harmful gases and prevent safety risks.
Furthermore, the storage place should be away from fire and heat sources. Because it may be flammable, it is easy to burn or even explode in case of open flames and hot topics. It should also be stored separately from oxidants, acids, bases, etc., to avoid mutual reaction and cause danger.
As for transportation, the packaging must be tight and sturdy to ensure that there is no leakage during transportation. When handling, it is necessary to handle it with care, and do not collide or fall, so as not to damage the packaging and cause material leakage. Transportation vehicles should also be equipped with corresponding fire equipment and leakage emergency treatment equipment to prevent accidents. And the transportation process should follow the designated route, avoiding densely populated areas and important places. In this way, 2-amino-5-chlorobenzothiazole is safe in storage and transportation, and its inherent quality is maintained.