As a leading 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester
2-Amino-5-bromothiazole-4-carboxylic acid methyl ester, this is an organic compound. In terms of physical properties, it is mostly solid under normal conditions. Due to factors such as intermolecular forces, it has a certain melting point. The specific melting point value will vary according to conditions such as purity. Appearance may be white to off-white crystalline powder, which is easy to observe and handle.
Chemically, its amino group is basic and can react with acids to form corresponding salts. For example, under suitable conditions, it can react with hydrochloric acid to form hydrochloric acid salts. 5-Bromine atoms are active and can participate in many substitution reactions. Under specific catalysts and reaction conditions, they can be replaced by other groups such as hydroxyl groups and amino groups. The thiazole ring, as an important structure of the compound, endows it with certain stability and unique reactivity. Its ester group can undergo hydrolysis reaction. In acidic or basic environments, the ester group will break to form corresponding carboxylic acids and alcohols. Under basic conditions, the hydrolysis reaction proceeds more rapidly and thoroughly. In addition, the compound may also participate in some condensation reactions and combine with other compounds containing active groups to form new compounds, which have potential application value in the field of organic synthesis.
What are the synthesis methods of 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester
Nowadays, there are methods for synthesizing 2-amino-5-bromothiazole-4-carboxylic acid methyl esters. The following are the common ones.
First, it can be obtained from a starting material containing a specific functional group through a multi-step reaction. First, the compound containing bromine and the reagent containing sulfur and nitrogen, under suitable reaction conditions, such as in a specific solvent, with appropriate temperature, catalyst, etc., condensation reaction occurs to form the prototype of the thiazole ring. In this step, attention should be paid to the precise control of the reaction conditions to avoid side reactions. Then, the obtained intermediate product is modified by carboxyl methyl esterification. The esterification reaction of alcohol and acid under the action of the catalyst is often used. The appropriate alcohol and catalyst are selected, and the reaction temperature and time are adjusted to promote the reaction to generate the target methyl ester. Finally, the amination reaction is carried out at a specific position on the thiazole ring to introduce amino groups to achieve the synthesis of 2-amino-5-bromothiazole-4-carboxylic acid methyl ester.
Second, another approach can also be found. Taking a thiazole derivative with a similar structure as the starting material, it is first brominated, and bromine atoms are introduced at a suitable position in the thiazole ring. This bromination reaction requires the selection of an appropriate bromination reagent and reaction environment to ensure the precise positioning of bromine atoms. Subsequently, the carboxyl group is converted into methyl ester group, and then the amino group is added at the predetermined position through specific amination means to obtain the target product. During the operation, the separation and purification of each step of the reaction is quite critical. According to the characteristics of the product and impurities, appropriate separation methods, such as extraction, column chromatography, etc., are selected to obtain high-purity 2-amino-5-bromothiazole-4-carboxylate methyl ester.
What is the main use of 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester?
2-Amino-5-bromothiazole-4-carboxylic acid methyl ester, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Geiinthiazole compounds have a variety of biological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. The functional groups of amino groups, bromine atoms and ester groups of this compound give it unique reactivity. It can be derived from various chemical reactions with many compounds with specific biological activities, which is of great significance in the process of new drug development.
In the field of materials science, it also has its application. With its structural properties, or can participate in the synthesis of specific materials, it endows materials with special properties, such as improving the stability and optical properties of materials. For example, after appropriate chemical modification, it can be used to prepare materials with special photoelectric properties, which may have potential applications in the fields of organic Light Emitting Diodes, solar cells, etc.
Furthermore, in the field of organic synthesis chemistry, as an important intermediate, complex organic molecular structures can be constructed by reacting with different reagents. Chemists can skillfully use their functional group properties to design and implement various organic synthesis routes, expand the structural diversity of organic compounds, and contribute to the development of organic synthesis chemistry.
What is the market price of 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester
I have not yet obtained the exact market value of 2-Amino-5-bromothiazole-4-carboxylic acid methyl ester. This compound is a special substance in the chemical field. Its market value is often affected by many factors.
First, the cost of raw materials is large. The general raw materials required for the manufacture of this compound, if their quality rises and falls due to local conditions, seasonal conditions, supply and demand, etc., the quality of the finished product will also be changed. If the required starting materials or due to the source of the product are sorry, it will be high and low.
Second, the cost of manufacturing and reproduction will vary. If this compound requires delicate and high-cost work, such as special catalysts, high-quality products, etc., it will increase the cost of production, which will push up the market. And if the cost is large, it will also increase the cost.
Third, the supply and demand of the market is the main reason for the fixed price. If the market demand for this compound is strong, but the supply is limited, if it is used in new materials research and other fields resulting in a large increase in demand, it will be necessary; conversely, if the supply is based on demand, the price will be reduced.
Fourth, the brand and the quality of the product also play a role. The quality of the product or the cost of quality control and other factors are higher than that of the ordinary company.
Only those who want to know the market, test the chemical raw material trading platform, supplier or related industry can get the price of the product.
2-Amino-5-bromothiazole-4-carboxylic acid methyl ester in storage and transportation
2-Amino-5-bromothiazole-4-carboxylic acid methyl ester is a kind of organic compound. During storage and transportation, it is necessary to pay attention to many matters.
When storing it, the first choice of environment. When placed in a cool, dry and well-ventilated place, do not expose it to high temperature or humidity. Due to high temperature, it is easy to cause the compound to decompose and deteriorate, and the humid gas may cause it to be damp, resulting in quality damage. In addition, it needs to be stored separately from oxidants, acids, bases and other substances. This is due to the chemical properties of this compound, which encounters with the above-mentioned substances, or reacts violently, or even causes dangerous accidents.
As for transportation, the packaging must be sturdy and tight. It is necessary to ensure that the packaging can withstand certain pressure and vibration to prevent the packaging from being damaged during transportation and causing the compound to leak. During transportation, direct sunlight should also be avoided. This compound may be sensitive to light, and light may affect its stability. At the same time, the environment of the transportation vehicle should also maintain a suitable temperature and humidity, and the transportation personnel must be familiar with the characteristics of this compound and emergency treatment methods. If there is an accident such as leakage during transportation, it can be properly disposed of in time to avoid greater harm. In conclusion, the storage and transportation of methyl 2-amino-5-bromothiazole-4-carboxylate should be carried out with great care and in accordance with regulations to ensure its safety and quality.