Chemical Formula | C5H9N3S |
Molar Mass | 143.21 g/mol |
Appearance | Solid (usually white or off - white) |
Odor | May have a faint, characteristic odor |
Solubility In Water | Limited solubility due to non - polar thiazole ring |
Solubility In Organic Solvents | Soluble in some polar organic solvents like ethanol |
Pka | Related to the basicity of amino groups, data may vary |
What is the main use of 2-AMINO-5- (AMINOMETHYL) -4-METHYLTHIAZOLE?
2-Amino-5- (aminomethyl) -4-methylthiazole, this substance has a wide range of uses. In the field of medicine, it is often a key intermediate, helping to create a variety of drugs. Geiinthiazole compounds have unique biological activities and show therapeutic potential for many diseases such as antibacterial, anti-inflammatory, and anti-tumor. Based on this substance, physicians can carefully construct specific structural drugs to precisely act on lesions and exert therapeutic effects.
In the chemical industry, it also plays an important role. Or participate in the synthesis of special functional materials, which give materials different properties due to their own structural characteristics, such as enhancing stability and changing optical properties. The amino and aminomethyl groups in the structure of this compound give it active reactivity, which can react ingeniously with many reagents, expand the material synthesis path, and meet the diverse needs of chemical production.
In agriculture, it may be used to develop new pesticides. In view of its impact on some biological activities, it is expected to develop pesticide products with high insecticidal, bactericidal or herbicidal effects. After rational design and modification, the compound can accurately act on pests, ensure the healthy growth of crops, improve agricultural output, and minimize the adverse effects on the environment and non-target organisms. From this perspective, 2-amino-5- (aminomethyl) -4-methylthiazole has key uses in many fields such as medicine, chemical industry, and agriculture, providing important assistance for the development of various industries.
What are the physical properties of 2-AMINO-5- (AMINOMETHYL) -4-METHYLTHIAZOLE
2-Amino-5- (aminomethyl) -4-methylthiazole is one of the organic compounds. Its physical properties are quite important, let me tell them one by one.
The state of this compound, under room temperature and pressure, is often solid, mostly white or off-white powdery substances, with fine texture and pure color. Its granular state makes it convenient to use and operate, easy to weigh and mix, and is quite practical in many chemical experiments and industrial production processes.
When it comes to the melting point, the melting point of this substance is about [X] ° C. The characteristics of the melting point are of key significance in the identification, purity determination and processing of compounds. The exact value of the melting point, like the unique identification of a compound, can help chemists distinguish its authenticity and purity.
In terms of solubility, 2-amino-5- (aminomethyl) -4-methylthiazole is slightly soluble in water, but its solubility is limited. However, in some organic solvents, such as ethanol, dichloromethane, etc., it shows relatively good solubility. The characteristics of this solubility provide an important basis for the selection of various reaction systems, as well as the process of separation and purification. Chemists can skillfully design the reaction environment and separation process according to the difference in solubility to achieve the desired chemical target.
In addition, the density of this compound is also an important physical property. Its density is about [X] g/cm ³. Although this value seems ordinary, it plays an indispensable role in the conversion of mass and volume of substances, as well as in the phase distribution of the mixed system. In the ratio of materials in chemical production and in the micro-reaction operation in the laboratory, the accurate knowledge of the density can ensure the accuracy of the experiment and the stability of the production.
As for its odor, 2-amino-5- (aminomethyl) -4-methylthiazole usually exudes a special odor, which is not pungent or intolerable, but also has a unique smell. This odor characteristic, in the actual operation process, can provide chemists with a certain sensory judgment basis to help them initially identify and distinguish.
What are the synthesis methods of 2-AMINO-5- (AMINOMETHYL) -4-METHYLTHIAZOLE
To prepare 2 - AMINO - 5- (AMINOMETHYL) - 4 - METHYLTHIAZOLE, the conventional number method. First, it can be formed by condensation and cyclization of sulfur-containing compounds and nitrogen-containing reagents. First, take an appropriate sulfur source, such as thioamide, and a nitrogen source with amino groups and methyl groups, in a suitable solvent, under the catalysis of acid or base, slowly heat to make the two condensation and cyclization. After complex processes such as intramolecular rearrangement, it gradually becomes this target.
Second, use halogenated compounds as starting materials. Choose a suitable halogenated methyl compound and react with nucleophiles containing sulfur and nitrogen. The sulfur and nitrogen atoms in the nucleophilic reagent initiate nucleophilic substitution of the halogen atoms of the halogen substitutes, and then cyclization in the molecule, which can also achieve this purpose. When reacting, pay attention to the proportion of reagents, reaction temperature and time, which are all related to the yield and purity of the product.
Third, with the help of biosynthesis. Find microorganisms or enzymes with specific enzyme systems, and use specific substrates to enzymatic reactions in vivo to obtain this compound. The method of biosynthesis has relatively mild conditions and good selectivity. However, it requires quite strict requirements on the biological system, and requires precise regulation of culture conditions and substrate supply.
All these methods have advantages and disadvantages. The chemical synthesis process is mature, the yield is controllable, but the steps are cumbersome, and the reagents are toxic or large; the biosynthesis method is green and environmentally friendly, with excellent selectivity, but the technical threshold is high, and large-scale production is not easy. In actual preparation, careful choices should be made according to factors such as demand, cost, and environment.
What is the price of 2-AMINO-5- (AMINOMETHYL) -4-METHYLTHIAZOLE in the market?
There is a question today, what is the price of 2-amino-5- (aminomethyl) -4-methylthiazole in the market. This is a compound in the field of fine chemicals, and its price is affected by many factors, making it difficult to be sure.
First, purity is the key. If the purity is extremely high, it is almost pure in chemical analysis or higher, and it is suitable for high-end scientific research experiments, and its price is high. Gai because its preparation requires fine technology and strict purification process, the cost is greatly increased, or it can reach tens or even hundreds of yuan per gram.
Second, the scale of mass production is also affected. If the manufacturer can mass-produce, due to the scale effect, the unit cost can be reduced, and the price will also decrease. On the contrary, small-scale production, the cost is difficult to control, and the price is high.
Furthermore, the market supply and demand relationship cannot be ignored. If the market demand for this product is strong, but the supply is limited, merchants may raise prices in response. On the contrary, if the demand is low and the supply is sufficient, the price will be reduced.
Again, the cost of raw materials is also an important factor. The price fluctuation of raw materials required for the synthesis of this compound is directly related to its production cost, which in turn affects the selling price.
In addition, the sales area and channels are different, and the price is also different. In developed regions or specific professional markets, the price may be slightly higher due to factors such as operating costs. Therefore, if you want to know the exact price, you need to consult the relevant chemical product suppliers in detail, compare the quotations of various companies, and comprehensively consider the above factors to obtain a more accurate price.
What are the storage conditions for 2-AMINO-5- (AMINOMETHYL) -4-METHYLTHIAZOLE?
2-Amino-5- (aminomethyl) -4-methylthiazole is a very important chemical substance, and its storage conditions are crucial to its quality and stability. When this substance is stored, the drying environment is the first. Because of its certain hygroscopicity, if placed in a humid environment, it is easy to absorb water vapor, causing its properties to change, or even chemical reactions to occur, damaging purity and activity. Therefore, it should be stored in a dry place, and a desiccant can be prepared next to the storage container to keep the environment dry.
The second time is to control the temperature. Generally speaking, it should be stored in a cool place to avoid high temperature. High temperature can easily intensify the molecular movement of the substance, accelerate the chemical reaction, or cause decomposition and deterioration. It is generally recommended that the storage temperature be 2-8 ° C. This temperature range can effectively slow down the rate of physical and chemical changes and prolong the shelf life.
Furthermore, pay attention to the choice of storage containers. It is advisable to use containers with good sealing to prevent excessive contact with air. Oxygen, carbon dioxide and other components in the air, or oxidation, acid-base reaction with the substance, etc. It is better to use sealed containers made of glass or specific plastics. Such containers are relatively stable in chemical properties and are not easy to react with 2-amino-5- (aminomethyl) -4-methylthiazole.
In addition, the storage place should be kept away from fire sources, heat sources and strong oxidizing agents. The substance may be flammable to a certain extent, and it is dangerous to burn in case of open flames and hot topics; strong oxidizing agents may also react violently with it, causing safety accidents. Be sure to place it in a safe and independent storage area, and make corresponding warning signs to ensure the safety of the storage process. In this way, a good storage effect can be achieved, so that 2-amino-5- (aminomethyl) -4-methylthiazole can maintain its inherent properties and efficacy for a long time.