2 Amino 4 Thiazolecarboxylic Acid Ethyl Ester
quinoline thiophene imidazole thiazole

2-Amino-4-Thiazolecarboxylic acid ethyl ester

    Specifications

    HS Code

    485998

    Chemical Formula C6H8N2O2S
    Molecular Weight 172.205 g/mol
    Appearance Typically white to off - white solid
    Melting Point Data may vary, around 140 - 145 °C approximately
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol, acetone
    Odor Odorless or very faint odor
    Purity Can be obtained in high purity, e.g., 98%+ in commercial products
    Stability Stable under normal storage conditions away from heat, light and oxidizing agents

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    Frequently Asked Questions

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    What are the physical properties of 2-Amino-4-Thiazolecarboxylic acid ethyl ester
    2-Amino-4-thiazolecarboxylate ethyl ester, this is an organic compound. Its physical properties are quite unique.
    Looking at its morphology, under room temperature and pressure, it is mostly white to light yellow crystalline powder, which makes it easy to distinguish among many substances.
    As for the melting point, it is about a certain temperature range. Due to different preparation methods and purity, it is slightly different, but the approximate range can be investigated. The characteristics of the melting point are crucial in the identification and purification of substances.
    Its solubility can also be followed. In organic solvents, such as ethanol, acetone, etc., it shows a certain solubility. However, in water, the solubility is relatively limited. This difference in solubility is closely related to the molecular structure of the compound. The polar and non-polar parts of the molecule interact, causing it to behave differently in different solvent environments.
    Furthermore, its density is also an important physical parameter. Although the exact value needs to be accurately measured, it can be seen that its density is in a certain range according to the law of its structure and similar compounds. This density characteristic plays a significant role in practical application scenarios such as chemical production and material separation.
    In addition, the compound is stable under normal conditions. However, when exposed to extreme conditions such as high temperature, strong acid, and strong alkali, the molecular structure may change, causing its physical properties to change accordingly.
    In summary, the physical properties of ethyl 2-amino-4-thiazole carboxylate are key factors to consider in chemical research, chemical production, and related fields.
    What are the chemical properties of 2-Amino-4-Thiazolecarboxylic acid ethyl ester
    Ethyl 2-amino-4-thiazole carboxylate is an organic compound with unique chemical properties. Its appearance is often white to off-white crystalline powder, which is widely used in many chemical fields.
    In terms of solubility, it exhibits specific solubility properties in organic solvents. In common organic solvents such as ethanol and acetone, it has a certain solubility. This property makes it easy to disperse in the reaction system when it is used as a reactant or intermediate in organic synthesis reactions, which is conducive to the smooth progress of the reaction.
    From the perspective of chemical activity, the amino and ester groups of 2-amino-4-thiazole carboxylate ethyl ester have high reactivity. Amino groups can participate in many nucleophilic substitution reactions, react with acyl halides, acid anhydrides, etc., to form amide compounds. The ester group can undergo hydrolysis reaction under acid or base catalysis to generate corresponding carboxylic acids and alcohols. Hydrolysis under alkaline conditions is relatively easy, and this hydrolysis reaction is commonly used in the preparation of related thiazole carboxylic acid derivatives.
    Furthermore, the thiazole ring structure of ethyl 2-amino-4-thiazole carboxylate gives it certain stability and unique electronic effects. The conjugation system of the thiazole ring affects the electron cloud distribution of the molecule, making the compound exhibit special selectivity and reactivity in some reactions.
    Due to the various active groups contained in its structure, ethyl 2-amino-4-thiazolecarboxylate can be used as a key intermediate in the field of medicinal chemistry for the synthesis of biologically active drug molecules; in the field of pesticide chemistry, it can also be used to create new pesticides to meet the needs of pest control.
    In short, ethyl 2-amino-4-thiazolecarboxylate, with its diverse chemical properties, occupies an important position in many fields such as organic synthesis, medicine, and pesticides, and is of great significance for promoting the development of related fields.
    What is the main use of 2-Amino-4-Thiazolecarboxylic acid ethyl ester?
    Ethyl 2-amino-4-thiazolecarboxylate is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry.
    In the process of pharmaceutical research and development, this compound can be used to create antibacterial and antiviral drugs. Because of its unique chemical structure, it can combine with specific biological targets, thereby interfering with the life activity process of pathogens and achieving the effect of treating diseases. For example, when synthesizing some new antibacterial drugs, ethyl 2-amino-4-thiazolecarboxylate can be integrated into the molecular structure of the drug through a series of chemical reactions, giving the drug stronger antibacterial activity and selectivity.
    In the field of pesticide chemistry, it can also be seen. It can be used as a raw material for the synthesis of new pesticides, and can develop insecticides and fungicides with high efficiency and low toxicity. With its specific effect on the physiological mechanism of harmful organisms, it inhibits or kills pests and pathogens, and protects farmers and mulberry to ensure the thriving growth of crops.
    Furthermore, in the field of organic synthetic chemistry, 2-amino-4-thiazolecarboxylate ethyl ester can participate in a variety of organic reactions due to its rich reaction check points, providing a basis for the construction of more complex organic molecular structures, helping organic synthetic chemists to create various organic compounds with special properties and uses. All of this highlights its significant status and role in many chemistry-related fields.
    What is the synthesis method of 2-Amino-4-Thiazolecarboxylic acid ethyl ester
    The synthesis method of ethyl 2-amino-4-thiazole carboxylate, although the ancient book "Tiangong Kaiwu" does not directly describe this compound, its chemical synthesis principle may be analogous to ancient techniques.
    In the past, if you want to make this product, you can first take a suitable thiazole derivative as the base. Using it as the starting material, in a specific reaction vessel, add an appropriate amination reagent. This reagent needs to be carefully selected so that it can aminate with a specific part of the thiazole derivative to introduce an amino group. During the reaction, temperature, pressure and reaction time are all critical. The temperature should be stable, not high or low, otherwise the reaction may be biased or stagnant; the pressure should also be adjusted to just the right place to help the reaction proceed smoothly; the duration depends on the signs of the reaction and careful observation to ensure the successful access of the amino group to obtain the thiazole intermediate containing the amino group.
    Then, the intermediate meets the carboxylic acid ethyl esterification reagent. This process also needs to be careful, and mild reaction conditions should be selected to prevent overreaction or side reactions. The pH of the reaction environment also needs to be fine-tuned to make it in the optimum range, so as to promote the smooth reaction of the carboxyl group of the intermediate with the ethyl esterification reagent, and finally form 2-amino-4-thiazole carboxylate ethyl ester.
    The whole process of synthesis has strict requirements on the purity of raw materials and the cleanliness of reaction equipment. If impurities exist, the reaction sequence will be disrupted, resulting in impure products. Unclean equipment also interferes, making the reaction difficult to achieve expectations. Therefore, every step requires fine operation and micro-knowledge to prepare pure 2-amino-4-thiazole carboxylate ethyl ester.
    2-Amino-4-Thiazolecarboxylic acid ethyl ester in storage and transportation
    Ethyl 2-amino-4-thiazolecarboxylate is an important organic compound. During storage and transportation, many things need to be paid attention to.
    When storing, the drying environment is the first priority. Because it is easily affected by water vapor, if the environment is humid, or it causes reactions such as hydrolysis, it will damage its quality. Therefore, it should be stored in a dry and well-ventilated place, away from water sources and places with high humidity.
    Temperature is also critical. This compound is more sensitive to temperature. Excessive temperature may cause structural changes and change properties. Usually it should be stored in a cool place, generally 2-8 ° C. For details, it can be adjusted according to the product manual.
    Furthermore, it is necessary to avoid contact with oxidants, acids, alkalis and other substances. Because of its specific chemical activity, it encounters with the above substances, or triggers violent chemical reactions, such as oxidation, acid-base neutralization, etc., not only causes its own deterioration, but also may cause safety accidents.
    When transporting, the packaging must be stable. This compound is mostly in solid or liquid form, and stable packaging can prevent it from leaking during transportation bumps. It is often loaded in a sealed container to ensure that there is no risk of leakage.
    Temperature should be controlled during transportation. According to its temperature requirements, choose a suitable transportation method, such as refrigerated transportation, to ensure stable temperature during transportation.
    In addition, transporters should be familiar with its chemical properties and emergency treatment methods. If there is a leak during transportation, it can be disposed of quickly and correctly to reduce the harm.
    In short, the storage and transportation of 2-amino-4-thiazole ethyl carboxylate must strictly follow the relevant specifications and requirements to ensure its quality and transportation safety.