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What are the main uses of 2-AMINO-4-BROMOBENZOTHIAZOLE?
2-Amino-4-bromobenzothiazole is an important class of organic compounds. Its main uses are extensive and are described below.
In the field of medicine, this compound is often a key raw material for traditional Chinese medicine. Medicinal chemists use it as a basis to carefully design and synthesize a variety of drug molecules with specific biological activities. Because of its unique chemical structure, it can precisely bind to specific targets in organisms and exhibit various pharmacological activities such as antibacterial, anti-inflammatory, and anti-tumor. For example, after ingenious modification, it may interfere with specific metabolic pathways of tumor cells, thereby inhibiting tumor cell proliferation and opening up new avenues for the development of anti-tumor drugs.
In the field of pesticides, 2-amino-4-bromobenzothiazole also plays an important role. High-efficiency pesticides can be prepared, which have strong toxic effects on many pests, and are relatively friendly to the environment, with low residues. This compound can precisely act on the specific physiological system of pests, or destroy the normal function of their nervous system, or interfere with the operation of their respiratory system, making it difficult for pests to survive, effectively ensuring crop yield and quality.
Furthermore, in the field of materials science, it also has good performance. It can participate in the synthesis of functional materials with excellent performance. For example, the preparation of materials with special optical and electrical properties is widely used in photoelectric displays, sensors and other fields. Due to its structure, the material can be endowed with a unique electron cloud distribution, which in turn affects the optical absorption and emission characteristics of the material, meeting the strict requirements of material properties in different scenarios.
In addition, in organic synthesis chemistry, 2-amino-4-bromobenzothiazole is often used as a key intermediate. With its active functional groups, complex and diverse organic compounds can be constructed through various organic reactions, greatly enriching the variety of organic compounds, injecting strong impetus into the development of organic synthesis chemistry.
In summary, 2-amino-4-bromobenzothiazole has important uses in many fields such as medicine, pesticides, materials science and organic synthesis, and has made outstanding contributions to promoting the development of related fields.
What are the physical properties of 2-AMINO-4-BROMOBENZOTHIAZOLE?
2-Amino-4-bromobenzothiazole, this is an organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly in a solid state, and the color may be white to light yellow crystalline powder. This shape is conducive to storage and transportation, because it is relatively stable and is not easy to rapidly change the shape in conventional environments.
As for the melting point, it is about 190-194 ° C. The characteristics of the melting point are crucial for the identification of the compound and related separation and purification processes. If a mixture containing this compound is purified, the compound can be separated from the mixture according to its melting point characteristics by recrystallization and other methods to obtain a pure product.
In terms of solubility, it has little solubility in water. Water is a common solvent, and this compound is insoluble in water, which means that in an aqueous environment, it is mostly dispersed as solid particles or precipitated at the bottom of the water. However, it is soluble in organic solvents such as ethanol and dichloromethane. Organic solvents such as ethanol and dichloromethane have specific chemical structures and polarities, and can form interactions such as hydrogen bonds and van der Waals forces with 2-amino-4-bromobenzothiazole molecules, so they can be dissolved. This solubility property is of great significance in organic synthesis reactions. Researchers can choose a suitable organic solvent according to the needs of the reaction to fully dissolve the compound, so as to facilitate the smooth progress of the reaction and improve the reaction efficiency and yield. < Br >
The physical properties of 2-amino-4-bromobenzothiazole are fundamental and critical information in many fields such as chemical research and industrial production, providing an important basis for related operations and applications.
What is the chemical synthesis method of 2-AMINO-4-BROMOBENZOTHIAZOLE?
The chemical synthesis method of 2-amino-4-bromobenzothiazole, although the ancient book "Tiangong Kaiwu" does not directly describe the synthesis of this specific compound, it can be deduced from the ancient chemical process idea.
In the past, to prepare such compounds containing nitrogen, bromine and heterocycles, it often required multiple delicate reactions. The first step is to choose suitable starting materials, such as aromatic compounds containing sulfur and nitrogen. This may be derived from natural resources such as coal tar extracts, and purified and isolated to obtain pure products as the basis for synthesis.
Second, bromine atoms are introduced. The ancient method, or bromine and suitable catalysts, react under specific temperature and solvent conditions. The activity of bromine is quite high, but the selectivity needs to be carefully adjusted to prevent side reactions. With mild reaction conditions and catalysts, bromine atoms can be precisely settled at specific positions in the benzene ring to form 4-bromine intermediates. The key after
is to construct a benzothiazole ring and introduce an amino group. This step may be cyclized, and the reagents containing sulfur and nitrogen interact with the intermediates in the previous step. During cyclization, the temperature, reaction time and proportion of the reactants need to be carefully controlled to make the molecules cleverly cyclized. As for the introduction of amino groups, or the use of amination reagents, through nucleophilic substitution and other reactions, the final result is 2-amino-4-bromobenzothiazole.
Although the ancient process may be different from the present, its insight into the reaction conditions, the selection and regulation of raw materials, have laid the foundation for today's synthetic chemistry, enabling our generation to continuously optimize the synthesis method based on the ancient wisdom.
What is the price range of 2-AMINO-4-BROMOBENZOTHIAZOLE in the market?
2-Amino-4-bromobenzothiazole is on the market, and its price range is difficult to determine. This is due to changing market conditions, and the price varies with various factors such as supply and demand, quality, and provenance.
In the past, if you visit the chemical raw material market, you can see that the price varies depending on the quantity. If the purchase volume is quite large, such as the batch is measured in tons, the seller may promote the sale, and the price per kilogram may be slightly lower. However, if you only ask for a small amount, in grams, the price per gram must be high, covering the seller's need to take into account its operating costs, and the small transaction procedures are also complicated, so the price is high.
The concept of "Tiangong Kaiwu", although the price of this specific product is not detailed, it says that the price of all kinds of products is subject to many restrictions. As the book says and the genus of hardware, the price varies due to the abundance of ore sources and the difficulty of mining and smelting. 2-Amino-4-bromobenzothiazole is also the same. If the raw materials are easily available, the synthesis method is simple, and there are many products, the price may be flat. On the contrary, if the raw materials are rare, the preparation is difficult, and the production is small and there are many people seeking, the price will be expensive.
Roughly speaking, in the ordinary chemical market, the price per gram may be between a few dollars and tens of dollars; if it is wholesale in large quantities, it may be around a few hundred dollars per kilogram. However, this is only an approximate amount, and the actual price needs to be confirmed by various suppliers in the market.
What are 2-AMINO-4-BROMOBENZOTHIAZOLE manufacturers?
2-Amino-4-bromobenzothiazole is an important chemical raw material in organic synthesis. Its preparation involves a variety of chemical reactions and technologies, and is widely used in medicine, pesticides and other fields. Therefore, there are many manufacturers of such compounds, scattered all over the world.
In China, many fine chemical manufacturers are involved in the production of 2-amino-4-bromobenzothiazole. In the Yangtze River Delta and Pearl River Delta regions, the chemical industry is prosperous, and there is no shortage of such manufacturers. For example, some enterprises in Jiangsu can produce this compound stably with their profound chemical technology and complete industrial support. Some fine chemical enterprises in Zhejiang also use their own R & D strength to optimize production processes and ensure high-quality products. In Guangdong, some large-scale chemical enterprise groups integrate resources and produce 2-amino-4-bromobenzothiazole on a large scale to supply domestic and foreign markets.
Overseas countries, there are also many manufacturers participating in this field. In Europe, America and other places, some established chemical enterprises have a long history and advanced technology. They have technological and quality advantages in the production of 2-amino-4-bromobenzothiazole. For example, several chemical giants in Germany are famous for their rigorous production management and exquisite craftsmanship. Some professional fine chemical manufacturers in the United States focus on R & D and innovation to continuously improve product performance and meet high-end market demand.
In other Asian countries, such as India, the chemical industry has developed rapidly in recent years, and many companies have also participated in the production of 2-amino-4-bromobenzothiazole. With its cost advantage, it has won a share of the international market.
In general, 2-amino-4-bromobenzothiazole manufacturers are all over the world, and each manufacturer has shown its skills in the market according to its own advantages to meet the diverse needs of different industries for this product.