2-Amino-4,5,6,7-tetrahydrobenzothiazole

2-Amino-4,5,6,7-tetrahydrobenzothiazole is widely used in the chemical and pharmaceutical fields.
In chemical industry, it can be used as a key intermediate in organic synthesis. Based on this, a variety of complex organic compounds can be derived. For example, in dye synthesis, 2-amino-4,5,6,7-tetrahydrobenzothiazole can participate in the construction of the conjugate system of dye molecules through specific reaction steps, which affects the color, light and fastness of dyes, and helps to synthesize dyes with bright color and excellent performance. In the field of plastic additives, it is also useful. It can be chemically modified to access polymer segments to improve the thermal stability, oxidation resistance and other properties of plastics, and broaden the application scope of plastic materials.
In the field of medicine, this compound is of great significance. Many drug research and development are carried out with it as the core structure. Because of its unique chemical structure and biological activity, it can interact with specific biological targets. For example, in the design of some antibacterial drugs, the 2-amino-4,5,6,7-tetrahydrobenzothiazole structure can precisely act on the bacterial cell wall or protein synthesis-related targets, interfering with the normal physiological activities of bacteria, thus exerting antibacterial effect. In the study of anti-tumor drugs, it may also participate in the regulation of tumor cell signaling pathways, inhibit tumor cell proliferation, and provide new ideas and directions for solving cancer problems.
In summary, 2-amino-4,5,6,7-tetrahydrobenzothiazole plays an indispensable role in both chemical and pharmaceutical fields, promoting the development and progress of related industries.

2-Amino-4,5,6,7-tetrahydrobenzothiazole, this is an organic compound. Its physical properties are as follows:
Viewed at room temperature and pressure, it is mostly in a solid state, but it also depends on the specific purity and surrounding environmental conditions. As for the color, the pure one is usually a white to off-white powder. If it contains impurities, the color may change.
Smell, usually has a weak special smell, but this smell is not strong and pungent, but it can be felt close to the fine smell.
Touch, the density of the compound varies slightly due to different precise measurement conditions, roughly ranging from 1.3 to 1.5 g/cm ³. This density data reflects the relationship between mass and volume, and is in a certain density range compared with common organic solids.
Its melting point is about 150-160 ° C. When the temperature gradually rises to the melting point range, the compound gradually melts from solid to liquid. This property is of great significance in the identification, purity detection and related chemical operations of the compound.
As for solubility, it has limited solubility in water and is a slightly soluble substance. However, in organic solvents, such as methanol, ethanol, dichloromethane, etc., it exhibits good solubility. This difference in solubility stems from the difference in the molecular structure of the compound and the interaction between solvent molecules. In the process of organic synthesis, separation and purification, suitable solvents can be selected accordingly.

To prepare 2-amino-4,5,6,7-tetrahydrobenzothiazole, there are three methods. First, 2-bromo-1,3-propanediamine and thiocyanate are used as starting materials. First, 2-bromo-1,3-propanediamine and thiocyanate are heated together, and at an appropriate temperature and time, the two are combined in phase, and then cyclized to obtain this product. The raw materials are easy to obtain in this way, but the reaction conditions need to be fine-tuned. If the temperature is too high or the time is too long, the by-product may be generated, and the yield is not high.
Second, using 4,5,6,7-tetrahydrobenzothiazole-2-one as raw material, prepared by amination reaction. The 4,5,6,7-tetrahydrobenzothiazole-2-one is reacted with an ammonia source, such as liquid ammonia or amine compounds, in the presence of a catalyst. The catalyst can increase the reaction rate and make the reaction easier to proceed. This process requires control of reaction pressure and temperature. Improper pressure or temperature discomfort can affect the reaction process and product purity.
Third, using o-aminothiophenol and 1,3-dihalogenated propane as raw materials. The two are mixed in a suitable solvent first, and under the catalysis of alkali, through nucleophilic substitution reaction, the target product is formed after cyclization. The nature of the solvent, the type and dosage of the base are all related to the reaction effect. Choosing the right solvent and precisely adjusting the amount of base can promote the forward progress of the reaction and improve the yield and purity.
These three methods have their own advantages and disadvantages. In practical application, the optimal method should be carefully selected according to the availability of raw materials, cost, equipment conditions and product requirements.

2-Amino-4,5,6,7-tetrahydrobenzothiazole is in the market, what is the price? I searched all over the city, but it was difficult to find the exact price. This compound has a wide range of uses and is involved in medicine, chemical industry and other fields. However, its price varies depending on quality, quantity, source and market conditions.
Looking at past transactions, if it is a high-purity product and the quantity is small, the price per gram may reach tens of gold. Because of its preparation method, it may require exquisite craftsmanship and precious materials, so the cost is not cheap. If you buy in batches, the unit price may decrease due to the effect of scale.
Also, the price of things from different origins is also different. From a place with fine craftsmanship and high production capacity, due to the advantages of scale and technology, the price may be close to the people. And what is produced in a rare place, due to transportation, supply and demand, the price may be slightly higher.
Furthermore, the supply and demand of the city is also the key to the price. If there are many people who want it, and there are few suppliers, the price will be raised; conversely, if the market is full of goods, and there are few people who want it, the price will be reduced.
To sum up, if you want to know the exact price, you need to consider the quality, quantity, source and supply and demand of the city in detail. It is advisable to consult the supplier and compare the quotation to get a close price.

2-Amino-4,5,6,7-tetrahydrobenzothiazole is an important organic compound. Its storage conditions are crucial to its quality and stability.
When this compound is stored, the first environment is dry. Because of its certain hydrophilicity, if it is in a humid place, it is easy to absorb moisture and cause changes in properties, or initiate chemical reactions that damage its purity and activity. Therefore, it should be placed in a desiccator or in a closed container with a desiccant to keep it dry.
Temperature is also important for storage. It should be stored at a low temperature, usually 2-8 ° C. Low temperature can slow down the molecular movement, reduce the rate of chemical reaction, and prevent its decomposition or deterioration. Under high temperature, the molecular activity increases greatly, or causes structural changes, losing its inherent properties.
Furthermore, protection from light is also indispensable. Light, especially ultraviolet rays, can trigger photochemical reactions and cause structural damage to the compound. Therefore, it should be stored in a brown bottle or a container with light-shielding properties, and placed in a dark place to avoid direct contact with light.
In addition, the storage place should be away from fire sources, heat sources and strong oxidants. This compound may be flammable, and it is easy to cause danger when exposed to open flames and hot topics. Contact with strong oxidants may also trigger violent oxidation reactions, endangering safety.
In summary, the storage of 2-amino-4,5,6,7-tetrahydrobenzothiazole should adhere to the principles of dryness, low temperature, protection from light, and avoid coexistence with fire, heat and strong oxidants to ensure its quality and safety.