2-Amino-4-(4-bromophenyl)thiazole

2-Amino-4- (4-bromophenyl) thiazole is one of the organic compounds. It has a wide range of uses in the field of medicine and is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, or has various pharmacological activities such as antibacterial, anti-inflammatory, and anti-tumor. Therefore, those who develop medicine often use it to explore new therapies and drugs.
It also has its uses in the field of materials science. Or it can participate in the synthesis of materials with special functions, such as materials with photoelectric properties. Due to its structural properties, it may affect the electronic transport and optical properties of materials, and then be used in the development of organic Light Emitting Diodes, solar cells and other devices.
In addition, in the field of organic synthetic chemistry, this compound provides a basis for the construction of more complex organic molecules. Chemists can modify and derive it through various chemical reactions to create organic compounds with diverse structures and functions, contributing to the development of organic synthetic chemistry. In short, 2-amino-4- (4-bromophenyl) thiazole has shown important value and application potential in many scientific fields.

2-Amino-4- (4-bromophenyl) thiazole is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
First of all, its appearance is usually white to light yellow crystalline powder. This color and shape can be identified by the naked eye and simple observation means, and it is of great significance in the preliminary identification and quality judgment of the substance.
times and melting point, the melting point of this compound is about [X] ℃. For the melting point, the critical temperature at which the substance changes from solid to liquid is its inherent physical constant. Accurate determination of the melting point can be used to identify the purity of the compound. If the purity is high, the melting point is sharp and the melting range is narrow; if it contains impurities, the melting point decreases and the melting range becomes wider.
Another is solubility, 2-amino-4- (4-bromophenyl) thiazole exhibits specific solubility in common organic solvents. In organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), it has a certain solubility. This solubility provides a basis for its solvent selection in organic synthesis reactions. In water, its solubility is relatively low. Due to the large proportion of hydrophobic aromatic rings and thiazole rings in the molecular structure of this compound, the interaction between it and water molecules is weak.
In addition, its density is also an important physical property. Although the exact value or the measurement conditions are slightly different, it is roughly maintained at about [X] g/cm ³. Density is related to the relationship between the mass and volume of a substance, and is indispensable in practical operations such as measurement, separation and storage of substances.
In addition, the stability of this compound is also a consideration of physical properties. It is relatively stable under normal temperature and pressure, protected from light and moisture. In case of extreme conditions such as high temperature, strong acid and strong alkali, its structure may change, which affects its chemical properties and application efficiency.
In conclusion, the physical properties of 2-amino-4- (4-bromophenyl) thiazole, such as appearance, melting point, solubility, density, and stability, are factors that must be investigated and considered in detail when studying and applying this compound.

To prepare 2-amino-4- (4-bromophenyl) thiazole, the method is as follows:
Take 4-bromoacetophenone first, place it in a reactor with thiourea, and dissolve it in a suitable organic solvent, such as ethanol. Then add an appropriate amount of basic catalyst, such as sodium hydroxide or potassium carbonate, adjust it to a suitable temperature, about 60-80 degrees Celsius, and stir to fully react. This reaction lasts for several hours, during which the reaction process can be closely observed by thin-layer chromatography.
After the reaction is completed, the reaction liquid is cooled, the precipitated solid is collected by filtration, and then washed with cold water to remove its impurities. Then the product is purified by recrystallization with an appropriate organic solvent, such as ethanol-water mixed solvent, to obtain a relatively pure 2-amino-4- (4-bromophenyl) thiazole.
Or another method, the 4-bromobenzoic acid is used as the starting material, and 4-bromobenzoyl chloride is obtained by acid chlorination. Then it is reacted with thioacetamide under suitable conditions. This also requires the help of organic solvents and catalysts, and the reaction temperature and duration need to be finely adjusted. At the end of the reaction, the target product can also be obtained by cooling, filtering, washing and recrystallization according to the previous method. When operating, be sure to pay attention to safety. Organic solvents are flammable and toxic, and alkaline catalysts are also corrosive. When operating according to regulations, prevent accidents.

I have not been able to determine the price range of 2 - Amino - 4 - (4 - bromophenyl) thiazole in the market. The price of these compounds often varies due to changes in quality, purity, suppliers, purchase volume, and market supply and demand.
If you want to ask for its price, you can, as stated in "Tiangong Kaiwu", "The silk, hemp, fur and brown in the world are all of quality, so that the special face and color can be used. It is said that those who do not work hard to create things, I do not believe it", that is, you need to work hard to explore. You can go to the chemical raw material trading platform to scrutinize the quotations of various suppliers, such as Mobay, Gade Chemical Network, etc. These platforms gather many merchants, and the price list is often relatively complete.
You can also directly consult with chemical raw material suppliers to inform them of the required quality and quantity, and inquire about their offers. If the purchase volume is large, you may be able to get a preferential price. And in different regional markets, the price is also different. In places where the coastal chemical industry is concentrated, the price may be lower than that in the mainland due to sufficient supply.
In addition, a small amount of this product for research and development may be purchased from scientific research reagent suppliers, but its price may be slightly higher due to high packaging and purity requirements. In short, if you want to know its price, you must explore it in many ways and compare it to get an approximate price range.

2-Amino-4- (4-bromophenyl) thiazole, the manufacturer of this product is quite numerous in the world.
In China, many chemical companies are involved in the production of this product. Such as the fine chemical factories in Shanghai, with their exquisite craftsmanship and rigorous processes, they focus on the output of this compound. It is unique in the selection of raw materials and the control of reaction conditions. The products produced are of high quality and are favored by many downstream companies.
Another example is the Suhang area, where chemical leaders are also involved. Enterprises there rely on technological innovation and invest heavily in research and development. With cutting-edge technology and unremitting research, we have introduced new products in the production of 2-amino-4- (4-bromophenyl) thiazole, which not only produces considerable output, but also achieves great results in terms of product purity and stability.
Overseas countries also have no shortage of such manufacturers. Western countries have profound industrial heritage, and their chemical giants occupy the leading position in the global chemical industry. In the manufacture of 2-amino-4- (4-bromophenyl) thiazole, using advanced equipment and scientific management, the products are sold all over the world. The country of Toyo is famous for its fine chemicals. The company that produces this compound pays attention to details and strives for excellence in craftsmanship, and its products are renowned in the industry for their high quality.
The manufacturers of this compound are all over the world, each applying its own capabilities to meet the market demand for it.