What is the primary use of 2-Amino-3-thiazole-5-carboxaldehyde 96%?

2-Amino-1,3-thiazole-5-carboxaldehyde (2-Amino-1,3-thiazole-5-carboxaldehyde), with a content of 96%, is widely used. In the field of medicinal chemistry, it is often used as a key intermediate to help synthesize drug molecules with specific biological activities. Due to its unique chemical structure, it can interact with many biological targets, laying the foundation for the development of antibacterial, antiviral, antitumor and other drugs.

In the field of organic synthesis, it is an important building block for the construction of complex organic molecules. With the reactivity of its aldehyde group and amino group, it can carry out a variety of organic reactions, such as condensation reaction, cyclization reaction, etc., to prepare novel organic compounds and provide raw materials for materials science, natural product total synthesis and other fields.

In agricultural chemistry, it may be used as a starting material for the synthesis of new pesticides, aiming to create high-efficiency, low-toxicity and environmentally friendly pesticides for pest control and crop harvest.

This compound has important value in many chemical-related industries and scientific research fields due to its high activity and unique structure. It is an important substance to promote the progress of chemical synthesis and related technologies.

2-Amino-1, 3-thiazole-5-carboxaldehyde 96% of the physical properties

2-Amino-1,3-thiazole-5-carboxylic aldehyde (content 96%), this substance has specific properties and has its own unique properties. Looking at its shape, at room temperature, or as a crystal-like body, the color is plain and light, mostly near-white state, its crystal shape is regular, angular, highlighting natural ingenuity. Touch it, delicate texture, or slightly brittle, you need to be careful between pinching.

Smell its taste, exude a special smell, not pungent bad taste, but has a unique charm, attracting people to explore its inner secrets. As for its solubility, it has extraordinary performance in organic solvents. In case of alcohol solvents, it can be moderately soluble. In water, although the degree of solubility is limited, it is not completely insoluble. This property is closely related to the groups contained in its molecular structure.

Its melting point is also an important physical property. After fine determination, it has a specific value. This temperature limit is the key to its solid-liquid transformation. When heated to the melting point, the solid body gradually melts and turns into a flowing liquid. This process is quietly orderly and follows the laws of physics. And its chemical activity is highlighted by the existence of amino groups, aldehyde groups and thiazole rings. It can play an important role in many chemical reactions. It is an important raw material for organic synthesis and has important uses in chemical, pharmaceutical and other fields.

2-Amino-1, 3-thiazole-5-carboxaldehyde 96% of the chemical properties

2-Amino-1,3-thiazole-5-carboxaldehyde (2-Amino-1,3-thiazole-5-carboxaldehyde), with a content of 96%, its chemical properties are as follows:

This compound contains an amino group and an aldehyde group, and both. The amino group is basic and can form a salt with an acid. The aldehyde group is active and can undergo a variety of reactions.

has an oxidation reaction. In case of weak oxidants such as tolan reagent, the aldehyde group is oxidized to a carboxyl group to give 2-amino-1,3-thiazole-5-carboxaldehyde ammonium salt; in case of strong oxidants, the amino group or is also affected. < Br >
Reductive reaction can occur. With a suitable reducing agent such as sodium borohydride, the aldehyde group is reduced to an alcohol hydroxyl group to obtain 2-amino-1,3-thiazole-5-methanol.

The aldehyde group can participate in nucleophilic addition, and under acid catalysis with alcohols, it forms hemiacetals, which in turn generate acetals and protect the aldehyde group. It is commonly used in organic synthesis.

With aldose and ketone containing α-hydrogen, under alkali catalysis, through hydroxyaldehyde condensation reaction, a carbon-carbon double bond is formed, and the molecular carbon chain is increased, which expands its structural complexity. The amino group can participate in the substitution reaction, react with acyl halide, acid anhydride, etc., and the amino hydrogen is replaced by an acyl group to prepare derivatives containing amide bonds. It can also react with halogenated hydrocarbons to obtain N-alkylated products.

Its thiazole ring has certain aromatic properties and is relatively stable, but the electron cloud density distribution on the ring changes due to the influence of amino groups and aldehyde groups, resulting in its unique chemical activity, which provides the possibility for specific reactions.

2-Amino-1, 3-thiazole-5-carboxaldehyde 96% of synthetic methods

2-Amino-1,3-thiazole-5-carboxaldehyde (2-Amino-1,3-thiazole-5-carboxaldehyde) is an important organic compound, and its synthesis method is often based on chemical principles and traditional techniques.

One of the methods may start from the raw materials containing sulfur and nitrogen. First, take the appropriate sulfur source and nitrogen source to cause the condensation reaction to occur to construct the structure of the thiazole ring. For example, under the conditions of suitable solvents and reactions, the nucleophilic substitution and cyclization reactions may be initiated, and the intermediate containing thiazole structure can be obtained gradually. In this step, it is necessary to pay attention to the ratio of reaction temperature, time and reactants. If the temperature is too high or side reactions occur, if it is too low, the reaction will be delayed. Time control is also critical. If the reaction is too short, it will be too long or the product will be lost.

Then, modify the obtained intermediate to introduce an amino group and an aldehyde group. The introduction of an amino group can be done by nucleophilic substitution, reductive amination, etc. If the nucleophilic substitution is used, the appropriate active halogenated intermediate and ammonia or amine reagent are selected to allow the amino group to be connected smoothly. The introduction of an aldehyde group, or the oxidation method, oxidizes a specific alcohol group to an aldehyde group, and a mild oxidizing agent, such as Dess-Martin reagent, is selected to prevent excessive oxidation to carboxylic acids.

There is also a synthesis method, using the existing thiazole derivatives as the starting materials. Functional group transformation is carried out at its specific position, and the purpose of generating the target product is achieved through multi-step reaction. First, a functional group of thiazole derivatives is modified, such as esterification, halogenation, etc., to obtain a suitable intermediate, and then through a series of reactions such as hydrolysis, oxidation, and amination, the final product is 2-amino-1,3-thiazole-5-formaldehyde. In this path, the separation and purification after each step of the reaction is quite important, which can ensure the purity of the intermediate, which is conducive to subsequent reactions and improves the yield and purity of the final product.

In short, there are various methods for synthesizing 2-amino-1,3-thiazole-5-formaldehyde, each method has its advantages and disadvantages, and it is necessary to choose carefully according to actual needs, raw material availability and controllability of reaction conditions, etc., in order to obtain this product efficiently.

2-Amino-3-thiazole-5-carboxaldehyde 96% What is the price range on the market?

Looking at your question, I am inquiring about the price range of 2 - Amino - 1,3 - thiazole - 5 - carboxaldehyde 96% in the market. However, the market is fickle, this price also changes with many reasons, such as supply and demand, cost of system, time difference, place difference, and even business strategy.

In the past, the price of chemistry often varies greatly due to the wide and narrow sources of production and the number of seekers. If there are many people who want this product, the price is low; conversely, if there are few people who want it, the price must be high.

And the cost of control is also a major factor. The price of raw materials, the difficulty of making, and the simplicity of the workmanship are all related to the final selling price. It also affects the time and place, and the age is different, and the need or difference; the distance and proximity of the place also vary in transportation costs.

Although it is difficult to determine the range of its price, it is common sense that if you want to know the price of this 96% purity, you should consult the business of chemical raw materials, or look at professional chemical trading platforms, to get a near-real price. Or a few yuan per gram, or dozens of yuan per gram, are unknown, only by really exploring can you get the exact number.