2-amino-1,3-benzothiazole-6-carboxylic acid

2-Amino-1,3-benzothiazole-6-carboxylic acid, which has an amphoteric acid-base. Because it contains amino groups, it is basic and can form salts with acids; it also contains carboxyl groups, which are acidic and can react with bases.
In terms of solubility, carboxyl groups and amino groups can form hydrogen bonds with water, so they have a certain solubility in polar solvents, especially water. However, benzothiazole ring has a hydrophobic structure, which limits its solubility and is difficult to dissolve in non-polar solvents.
In terms of stability, benzothiazole ring has a stable structure and is not easy to decompose under general conditions. However, amino groups and carboxyl groups have high activity and can react under high temperature, strong acid, strong base or specific catalysts. For example, carboxylic groups can be esterified to form esters with alcohols under acid catalysis; amino groups can participate in nucleophilic substitution reactions and react with electrophilic reagents such as halogenated hydrocarbons.
In addition, due to the conjugated system, the compound has certain optical properties and can absorb specific wavelengths of light. There are absorption peaks in the ultraviolet-visible spectral region, which can be used for qualitative and quantitative analysis.

2-Amino-1,3-benzothiazole-6-carboxylic acid, which has a wide range of uses. In the field of medicine, it is often the key raw material for the synthesis of many specific drugs. Due to its unique structure and specific biological activity, it can be chemically modified and transformed to create therapeutic drugs for specific diseases, such as for the development of antibacterial and antiviral drugs, which interfere with the physiological process of pathogens by accurately acting on specific targets of pathogens, achieving the effect of inhibiting or killing pathogens; or for the development of anti-tumor drugs, which play an anti-cancer effect by affecting the growth, proliferation and metastasis mechanisms of tumor cells.
In the field of materials science, it can be used as a synthetic monomer of functional materials. With its special chemical structure, it can endow materials with unique properties such as fluorescence properties and stability enhancement. For example, the synthesis of fluorescent materials with specific fluorescence emission wavelengths can be used in the field of biological imaging to provide high-sensitivity markers for cell and tissue observation; or it can be used to prepare high-performance polymer materials to improve the mechanical properties and thermal stability of materials, etc., which are very useful in industries such as aerospace and electronic devices that require strict material properties.
In agriculture, 2-amino-1,3-benzothiazole-6-carboxylic acids can participate in the synthesis of new pesticides. Its structure can be used to design and synthesize high-efficiency, low-toxicity and environmentally friendly pesticides for crop pests and pathogens. Targeting the nervous system or pathogen metabolic pathways of specific pests can reduce the impact on non-target organisms, safeguard the agricultural ecological environment, and contribute to the sustainable development of agriculture.

There are several methods for the synthesis of 2-amino-1,3-benzothiazole-6-carboxylic acid. One method is to use anthranilic acid as the starting material, and first heat it with ammonium thiocyanate to form a thioamide intermediate. This step requires temperature control and control of the reaction time. For example, when heated at a suitable temperature for a number of times, the corresponding thioamide can be obtained. Then cyclization under appropriate conditions can be used to generate 2-amino-1,3-benzothiazole-6-carboxylic acid by specific reagents and reaction conditions. The selection of solvent and the adjustment of pH in this process are all related to the yield and purity of the product. < Br >
There is another method in which benzothiazole derivatives containing suitable substituents are used as starting materials, amino groups are introduced through amination reaction, and then carboxylation steps are taken to form the target product. During amination, suitable amination reagents, such as ammonia or specific amine compounds, need to be selected to promote the introduction of amino groups according to the reaction conditions. Carboxylation depends on suitable carboxylation reagents and conditions, or is carried out in an alkaline environment or under specific temperature and pressure to achieve the purpose of carboxylation.
Another way is to start from benzoic acid derivatives containing specific substituents and construct benzothiazole rings through multi-step reactions and introduce amino groups. First, the benzothiazole skeleton is constructed by a specific reaction, and then the amino group is introduced at a suitable position. Each step of the reaction requires attention to the precise control of the reaction conditions, such as temperature, catalyst dosage, etc., to obtain a higher purity of 2-amino-1,3-benzothiazole-6-carboxylic acid. All these methods have advantages and disadvantages, and the experimenter should choose according to the actual needs and conditions.

I have no confirmation of the price range of "2-amino-1,3-benzothiazole-6-carboxylic acid" in the market. However, there are various ways to know the price of this product. First, you can consult chemical reagent suppliers, such as Sinopharm Group Chemical Reagent Co., Ltd., search banner reagent company, etc. These suppliers often sell a variety of chemical products, and their websites or customer service offices may be able to get the price details of the product. Second, explore chemical product trading platforms, such as Gade Chemical Network. On the platform, many merchants list products and prices for comparison. Third, look at relevant academic literature, industry reports, or get price-related clues, such as market trends, cost factors, etc. Although not direct prices, it is also helpful to estimate. However, the price of this substance may vary depending on purity, packaging, purchase volume, and market supply and demand. High purity prices may be high, and large purchases may have discounts. And market supply and demand change, and prices fluctuate accordingly. Therefore, in order to obtain accurate prices, it is necessary to consult suppliers or study relevant platforms in detail according to the actual purchase time, place, and conditions.

2-Amino-1,3-benzothiazole-6-carboxylic acid, this is a fine chemical substance. Its storage conditions are crucial, and it is related to the quality and utility of this substance.
This substance should be placed in a cool place, protected from direct sunlight. The heat and light of sunlight can cause its chemical reaction and cause it to deteriorate. Such as the hot summer sun, direct exposure to this substance, or make its structure mutate, losing its inherent nature.
It is also necessary to keep a dry environment and avoid humid places. Moisture can easily make this substance deliquescent, or cause hydrolysis reactions. For example, when it is raining in the south of the Yangtze River, the air humidity is high, if this substance is not properly preserved, it may change.
Furthermore, it should be placed in a sealed container. Oxygen, carbon dioxide, etc. in the air, or react with them. The seal can prevent the intrusion of external gases and ensure its stability.
The place where the chemical is stored should also be kept away from fire and heat sources. This chemical is heated, or there is a risk of combustion or explosion, which endangers safety.
In summary, 2-amino-1,3-benzothiazole-6-carboxylic acid should be stored in a cool, dry, sealed place, and away from the source of fire and heat, so that its quality can be maintained for future use.