2 6 Diobromo 2 Methyl 4 Trifluoromethyox 4 Trifluoromethyl 1 3 Thiazole 5 Carboxanilide
quinoline thiophene imidazole thiazole

2',6'-diobromo-2-methyl-4'-trifluoromethyox-4-trifluoromethyl-1,3-thiazole-5-carboxanilide

Taiy Chemical

Specifications

HS Code

832803

Chemical Formula C12H6Br2F6NO2S
Molar Mass 492.04 g/mol
Appearance Solid (presumably, based on typical thiazole - carboxanilide compounds)
Physical State At Room Temperature Solid
Solubility In Water Low (due to non - polar fluoromethyl and thiazole groups)
Solubility In Organic Solvents Moderate to high in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low
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General Information
Frequently Asked Questions
What are the chemical properties of 2 ', 6' -dibromo-2-methyl-4 '-trifluoromethyl-4-trifluoromethyl-1,3-thiazole-5-formylaniline
2%27%2C6%27-%E4%BA%8C%E6%BA%B4-2-%E7%94%B2%E5%9F%BA-4%27-%E4%B8%89%E6%B0%9F%E7%94%B2%E6%B0%A7%E5%9F%BA-4-%E4%B8%89%E6%B0%9F%BA-1%2C3-%E5%99%BB%E5%94%91-5-%E7%94%B2%E9%85%B0%E8%8B%AF%E8%83%BA, this is a complex organic compound. Its chemical properties are quite unique and have many characteristics.
This compound exhibits certain reactivity due to its specific functional groups. Among them, the structure of 2-methyl groups makes the molecular steric barrier different, which affects the orientation and rate of reaction with other substances. However, 4 '-trifluoromethoxy and 4' -trifluoromethyl groups, due to the high electronegativity of fluorine atoms, cause the distribution of molecular electron clouds to change, enhancing the stability and hydrophobicity of the compound.
In the nucleophilic substitution reaction, the compound has a selective reaction check point due to its structure. For example, the nitrogen and oxygen atoms of the 1,3-oxazole-5-acetamide part can be used as a nucleophilic reaction check point to react with suitable electrophilic reagents to form new chemical bonds and build more complex molecular structures.
In the redox reaction, the performance varies depending on the reaction conditions and the oxidizing agent or reducing agent encountered. In case of mild oxidizing agents, carbon-containing double bonds or specific functional groups may be oxidized to form corresponding oxidation products; in case of strong reducing agents, some functional groups may be reduced, resulting in changes in molecular structure and properties. < Br >
And because it contains acetamide groups, under specific acid-base conditions, hydrolysis reactions can occur, amide bonds are broken, and corresponding carboxylic acids and amine compounds are formed, which in turn affect the overall chemical properties and functions of the compounds.
In addition, the hydrophobicity of the compound makes it a special way to interact with hydrophilic substances in solution systems, or it can self-assemble into specific structures, which has potential application value in the fields of materials science and drug delivery.
What are the application fields of 2 ', 6' -dibromo-2-methyl-4 '-trifluoromethyl-4-trifluoromethyl-1,3-thiazole-5-formylaniline
2% 27% 2C6% 27-dibromo-2-methyl-4% 27-trifluoromethoxy-4-trifluoromethyl-1% 2C3-benzodioxane-5-formamide, this compound is used in the fields of medicine and pesticides.
In the field of medicine, it can be used as an active ingredient to develop new drugs due to its unique chemical structure. Modern medicinal chemistry studies have shown that specific fluorine-containing and bromine-containing structures often endow compounds with excellent biological activity and pharmacokinetic properties. The presence of trifluoromethyl and trifluoromethoxy in this compound may improve its lipophilicity, facilitate drug transmembrane transport, enhance affinity and binding ability to specific targets, or can be used to develop anti-cancer, antiviral and other drugs.
In the field of pesticides, the compound may have insecticidal, bactericidal, herbicidal and other activities. Halogen-containing atomic structures are widely used in the creation of pesticides. Bromine atoms can enhance the lipid solubility and stability of compounds. Trifluoromethyl and trifluoromethoxy can improve the biological activity and environmental adaptability of compounds. For example, it can be designed as an insecticide, which can interfere with the nervous system or physiological metabolic processes of insects by virtue of its special structure, achieve efficient insecticidal, and is relatively friendly to the environment. It has low residues and meets the needs of green pesticide development.
What is the preparation method of 2 ', 6' -dibromo-2-methyl-4 '-trifluoromethyl-4-trifluoromethyl-1,3-thiazole-5-formylaniline?
To prepare 2,6-dibromo-2-methyl-4 '-trifluoromethoxy-4-trifluoromethyl-1,3-benzodiazole-5-carboxylate benzyl ester, the following ancient method can be carried out.
First take an appropriate amount of phenolic compounds containing the corresponding substituents, put them in a suitable reaction vessel, use a base as a catalyst, and make them fully mixed with the halogenated trifluoromethoxy reagent. Control the reaction temperature in a mild range, and when stirring for a number of times, make the phenolic hydroxyl group undergo a nucleophilic substitution reaction with the halogenated trifluoromethoxy group to generate a phenolic derivative containing trifluoromethoxy. In this step, it is necessary to pay attention to the pH and temperature of the reaction system. If the pH is unbalanced or the temperature is too high or too low, the reaction rate may be affected, or even by-products may be formed.
After obtaining the above product, mix it with a bromine-containing reagent in a certain proportion and react in a solvent. The bromination reaction should be carried out at a low temperature and in the dark, in order to achieve the purpose of precise bromination and obtain 2,6-dibromo-substituted intermediates. During the reaction, the degree of bromination needs to be closely monitored to prevent excessive bromination.
Subsequently, this intermediate is combined with a suitable protective reagent to protect the hydroxyl or carboxyl groups at specific positions and avoid interference in subsequent reactions. The selection of the protecting group is crucial, and its stability and removal convenience must be taken into account.
Then the protected intermediate is reacted with a reagent containing methyl, trifluoromethyl and other groups under suitable catalyst and reaction conditions to introduce the corresponding substituent. This step requires strict control of the reaction conditions, such as temperature, pressure, reaction time, etc., to ensure that the substitution reaction occurs smoothly and has good selectivity.
After the successful introduction of each substituent, carefully remove the protecting group. The deprotection process should be handled gently to avoid damage to other groups in the molecule. Finally, through a series of separation and purification methods, such as column chromatography, recrystallization, etc., to remove impurities, pure 2,6-dibromo-2-methyl-4 '-trifluoromethoxy-4-trifluoromethyl-1,3-benzodiazole-5-benzyl formate products can be obtained. Throughout the preparation process, each step of the reaction requires fine operation and strict control of the reaction conditions to ensure the purity and yield of the product.
What is the market outlook for 2 ', 6' -dibromo-2-methyl-4 '-trifluoromethyl-4-trifluoromethyl-1,3-thiazole-5-formylaniline?
There are currently 2,6-di-tert-butyl-2-methyl-4 '-triethoxysilyl-4-triethylsilyl-1,3-dioxy-5-methylcyclopentenone, and its market prospects are related to many parties.
Looking at this compound, in the field of organic synthesis, its structure is unique, or it can be used as a key intermediate. With its specific group, or it can react with various reagents to form complex organic molecules, it may have potential in the preparation of fine chemical products. For example, in the synthesis of some high-value-added flavors and pharmaceutical intermediates, its special structure may endow the product with unique properties, so it may be in demand in the fine chemical market.
In materials science, silicon-containing groups are expected to participate in material modification. Triethoxysilane can be hydrolyzed and condensed to combine with the surface of inorganic materials to improve the interfacial properties of materials. For example, in the preparation of composite materials, the addition of this substance may enhance the bonding force between the matrix and the reinforcing phase, improve the mechanical properties of the material, and have application prospects in industries such as aerospace and automobile manufacturing that require strict material properties, and then open up related material markets.
However, its marketing activities also have challenges. Synthesis of this compound or process is complicated and costly, limiting large-scale production. And it takes time for the market to recognize and accept new compounds, and relevant application research needs to be in-depth. Only by joining hands with researchers and enterprises to deeply explore their performance and application, optimize the synthesis process and reduce costs, can we expand the market and make them shine in the fields of chemical industry and materials.
What is the safety of 2 ', 6' -dibromo-2-methyl-4 '-trifluoromethyl-4-trifluoromethyl-1,3-thiazole-5-formylaniline?
The name of this drug is 2,6-dichloro-2-methyl-4 '-trifluoromethoxy-4-trifluoromethyl-1,3-benzodiamide-5-methylpyridineformamide. Regarding its safety, let me tell you in detail.
This drug is both a drug and its safety is the first pharmacological properties. From its chemical structure analysis, the groups containing dichloro and trifluoromethyl may exhibit unique activities under specific conditions. However, these groups may also bring variables, or react specifically with substances in the body, affecting the normal physiological functions of the body.
On the toxicological level, after experimental investigation, if the dose is not properly controlled, it may cause damage to the liver, kidneys and other key organs of experimental animals. This may be due to the accumulation of some intermediate products in the organs during the drug metabolism process, interfering with the normal metabolic pathway.
Re-discussion of environmental effects. After this drug enters the environment, it is difficult to degrade rapidly due to its stable chemical structure. Its residue in soil and water bodies may affect the surrounding ecological balance and cause toxicity to non-target organisms, starting from the bottom organisms of the food chain and gradually spreading to the entire ecosystem.
In addition, during use, if the person applying the drug is not well protected, the drug may come into contact with the skin and respiratory tract, which may cause adverse reactions such as allergies and irritation. Long-term exposure to it is more likely to cause hidden and far-reaching harm to health.
Therefore, although this medicine has its effectiveness, there are many considerations for safety. When using it, it is necessary to strictly follow the regulations, take protective measures, and closely monitor the environmental impact to minimize the risk, so as to protect its benefits and avoid its harm.