2-(4-morpholinylmercapto)benzothiazole

"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty, in which the ceramic firing and other processes are described in detail. (4-zircon sand) The main use of zirconium silicate calcination, although it does not directly correspond to "Tiangong Kaiwu", it can be deduced from the ancient process principles and ceramic knowledge.
In ancient ceramic production, the selection and treatment of raw materials is extremely critical. After zirconium silicate is calcined, it may be used in ceramic bodies and glazes. For the body, it may enhance the strength and stability of the body. During ceramic firing, the body needs to withstand high temperature, and if the texture is not good, it is easy to deform and crack. After calcined, the characteristics of zirconium silicate may improve the structure of the green body, so that it maintains a good shape at high temperature, such as ancient famous kiln porcelain, the green body is solid and delicate, and there may be similar materials.
In the glaze, zirconium silicate may affect the texture and color of the glaze. Glaze is an important part of the ceramic surface, which is related to beauty and practicality. Calcined zirconium silicate may adjust the melting temperature and fluidity of the glaze to make the glaze uniform and smooth. And it may have an effect on the color of the glaze. Ancient ceramics have rich glazes, or due to the addition of special materials, zirconium silicate may be one of them, such as some celadon and white porcelain, the glaze color is pure and warm, or it benefits from the preparation of similar substances.
Although the "Tiangong Kaiwu" does not explicitly mention the use of zirconium silicate and calcination, the wisdom and practice of ancient ceramic technology may play an important role in the strengthening of green bodies and the optimization of glazes, contributing to the improvement of ceramic quality and technological development.

To prepare 2 - (4 - borylbenzyl) pyridyl pyrimidinone, there are various methods for its synthesis, which are described in detail below.
First, the key intermediate can be constructed through multi-step reaction, and then cyclized and condensed. First, take suitable starting materials, such as pyridine derivatives with specific substituents and boron-containing compounds, and undergo nucleophilic substitution to introduce boron groups into appropriate positions to generate boron-containing intermediates. In this process, attention should be paid to the precise control of reaction conditions, such as temperature and solvent selection, to ensure the smooth progress of the reaction and high selectivity.
Then, the boron-based intermediate and the pyrimidinone-related precursor are cyclized and condensed in the presence of a suitable catalyst. The key to this step lies in the selection of catalysts, such as transition metal catalysts, which use their catalytic activity to promote the formation of intramolecular rings, and then generate the target product 2- (4-borylbenzyl) pyrimidinone.
Second, you can also try to achieve synthesis by tandem reaction strategy. Select suitable starting materials and carefully design the reaction process to make multiple reactions occur in the same reaction system in sequence, avoiding cumbersome intermediate separation and purification steps. For example, using some special reagent combinations and reaction conditions, the pyridine ring and the pyrimidinone structural unit are gradually constructed and connected with the participation of boron groups to directly generate the target product. Although this strategy is challenging, if successfully implemented, it can greatly simplify the synthesis route and improve the synthesis efficiency.
Third, biosynthetic pathways can also be considered. Find specific biological enzymes or microorganisms, and use their unique catalytic activity and selectivity to bioconvert the corresponding substrates. Optimize the performance of biocatalysts through genetic engineering to enable them to efficiently convert suitable substrates into 2 - (4-borylbenzyl) pyrimidinone. Although this method is difficult to start with and requires in-depth understanding and control of biological systems, its advantages lie in green environmental protection, mild reaction conditions, and considerable development potential.
The above synthesis methods have their own advantages and disadvantages. Experimenters should carefully choose the appropriate synthesis path according to their actual conditions, such as experimental conditions, cost considerations, and requirements for product purity.

"Tiangong Kaiwu" cloud: Fu two lead (4-erbium photobasis) silver and mercury sound, its physical and chemical properties are different.
Lead is heavy and soft, silver-white in color, and has good ductility and corrosion resistance. At room temperature, lead is not easy to react violently with air and water, but in case of acid, it is easy to chemically react to form corresponding lead salts. Its melting point is low, about 327.5 ° C. This characteristic makes lead commonly used in casting and welding processes.
Silver, also a precious metal, is white and metallic, soft in texture, and has excellent ductility. It is the best in electrical and thermal conductivity among metals. The chemical properties of silver are relatively stable, and it is not easy to oxidize at room temperature. However, when it encounters sulfur or sulfide, black silver sulfide will be quickly formed, which is the reason why silverware turns black for a long time.
Mercury, commonly known as mercury, is the only metal that is liquid at room temperature and pressure. It has good fluidity, high surface tension, and looks like a silver-white pearl. Mercury has relatively stable chemical properties and is not easy to react with common acids and bases, but can form amalgam with some metals. Mercury has a low boiling point, about 356.7 ° C, and is volatile. Its vapor is toxic, so it needs to be used with extra caution.
Of these three substances, lead is heavy and soft, silver is precious and conductive, and mercury is liquid and volatile and toxic. Each has its own unique physical and chemical properties and has its important uses in different fields.

Now there are two, subtract (four and glazed radiance) the price range of amber radiance utensils in the market, which needs to be carefully considered before deciding.
The price of all kinds of utensils in the market often changes due to materials, craftsmanship, and the amount of existence. If this amber radiance utensils, its material is high-quality amber, and the craftsmanship is exquisite, the craftsman uses a noble method to blend the glazed radiance into it, so that it has both form and spirit, and its charm is extraordinary, the price will be very high.
In the city, if it is a common amber product in the folk, although it has the state of mutual radiance, the craftsmanship is ordinary, and the quality is not excellent. The price may be between several and dozens. If it is hidden by the dignitaries and dignitaries, it comes from the hands of famous craftsmen, and has a unique auspicious meaning, and the amber texture is crystal clear, the color is warm, and the glazed light is depicted in detail, the price of such utensils may be more than 100 yuan, or even thousands of gold.
Because the market situation is complicated, the supply and demand situation also affects the price. If everyone likes this amber exchange and has glazed light and auspicious utensils, and there are many people seeking but few things, the price will rise; on the contrary, if few people ask about it, even if the quality is excellent and the art is fine, the price will be difficult to be high. In order to determine its price range, it is necessary to widely observe the market conditions and the advantages and disadvantages of utensils in order to obtain a more accurate number.

2-%284-%E5%90%97%E5%95%89%E5%9F%BA%E5%B7%AF%E5%9F%BA%29%E8%8B%AF%E5%B9%B6%E5%99%BB%E5%94%91%E7%9A%84%E5%AE%89%E5%85%A8%E6%80%A7%E5%92%8C%E6%AF%92%E6%80%A7%E7%A5%9E%E7%A7%98%E8%80%8C%E5%8F%8D%E5%B9%B2%E7%94%9F%E7%89%A9%E4%B9%8B%E6%9C%BA%E5%88%B6, the ancient wise men have many inquiries.
This mixture is related to personal safety and health, and its properties need to be carefully examined. Although the (4-fluoroalkynyl) benzoxazole substances used in it are important for mixtures, their essential characteristics, in terms of safety and toxicity, have been studied in many ways.
Safe is related to whether the mixture can be used smoothly without harming the human body. If the ingredients in the mixture interact with each other, causing it to produce an unstable state, or contradicting the physiological mechanism of the human body, it is not a safe genus. Ancient alchemy is extremely cautious in the compatibility of drugs to ensure the safety of users. In this mixture, it is also necessary to carefully observe the fit of each ingredient to see if it changes in the human environment.
The toxic end is more critical. (4-fluoroalkynyl) benzoxazole substances have unique chemical structures or are potentially toxic. Toxic attacks can cause human discomfort, such as dizziness and nausea; severe damage can damage the viscera and endanger life. Ancient doctors used drugs like soldiers, and knew the harm of toxicity. Therefore, when developing new drugs, they must be tested many times. For this mixture, the ancient method should be used to test it with animals, observe its reaction, observe the changes in its viscera, and record the symptoms in detail. Then it can be gradually tried on a small scale in the human body and closely monitored to determine the presence and strength of its toxicity.
In summary, the safety and toxicity of Ximing 2- (4-fluoroalkynyl) benzoxazolopyridine must follow rigorous methods, follow ancient wisdom, verify many times, and study in detail. Only then can we gain insight into its properties and ensure its well-being for the user and avoid its harm.