2-(4-Methylphenyl)-benzothiazole

2-%284-Methylphenyl%29-benzothiazole is 2 - (4 -methylphenyl) benzothiazole, which has a wide range of uses and is mostly found in the fields of chemical industry, medicine and materials.
In the field of chemical synthesis, it is often used as a key intermediate. It can be derived from other compounds through various chemical reactions. Through specific reaction conditions and reagents, it can interact with many functional groups to derive products with different structures and properties, paving the way for the synthesis of other organic compounds and playing a significant role in the preparation of fine chemical products.
In the field of medicine, its biological activity and potential medicinal value have been widely explored. Some studies have shown that compounds containing this structure may have certain pharmacological activities, such as anti-tumor, antibacterial, and anti-inflammatory properties. Although it has not fully become a drug for clinical application, it provides key lead compounds for the research and development of new drugs, providing ideas and bases for the creation of new drugs with high efficiency and low toxicity.
In the field of materials, due to their unique structure and physicochemical properties, they may be applied to photoelectric materials. Due to their molecular structure or special optical and electrical properties, they can be used as functional materials in the research and development and manufacturing of photoelectric devices such as organic Light Emitting Diodes (OLEDs) and solar cells to improve device performance and efficiency.
In summary, 2 - (4 - methylphenyl) benzothiazole, with its diverse applications in chemical synthesis, pharmaceutical research and development, and materials science, plays an important role in the development of modern chemistry and related industries. With the progress of scientific research and technological innovation, its application prospects may be broader.

2-% 284 - Methylphenyl% 29 - benzothiazole is 2 - (4 - methylphenyl) -benzothiazole. The physical properties of this substance are quite important and are useful in many fields.
Looking at its properties, at room temperature, 2- (4 - methylphenyl) -benzothiazole is often in a solid state, mostly crystalline powders. Its color is white or white-like, and the texture is uniform and delicate.
When it comes to melting point, this compound has a specific melting point value, and usually changes from solid to liquid state within a certain temperature range. The specific melting point data, accurately determined by experiments, is between [X] ° C and [X] ° C. The stability of the melting point is one of the major characteristics of its physical properties, which is of great significance for identification and purity detection.
Besides solubility, the performance of 2- (4-methylphenyl) -benzothiazole in organic solvents varies. In common organic solvents such as ethanol and acetone, its solubility is good, and it can be moderately dissolved to form a homogeneous solution. However, in water, its solubility is very small, and this property is related to the polarity of its molecular structure. In its molecular structure, both the benzothiazole ring and the methylphenyl part have certain non-polarity, making it difficult to dissolve in water with strong polarity.
As for the density, the density of 2 - (4 - methylphenyl) -benzothiazole is also a fixed physical parameter, which is about [X] g/cm ³. The value of density is related to the space occupied by it in practical application and the quality relationship, and is indispensable in industrial production and experimental operation.
The physical properties of 2 - (4 - methylphenyl) -benzothiazole, such as solid state properties, specific melting point, solubility difference and density, are all important characteristics, which lay the foundation for research and application in many fields such as chemical industry and materials science.

To prepare 2 - (4 - methylphenyl) -benzothiazole, the common synthesis methods are as follows.
One is to use o-thiophenol and p-methylbenzoyl chloride as raw materials. First, the o-thiophenol and acid binding agent such as triethylamine are placed in an appropriate organic solvent such as dichloromethane, and the p-methylbenzoyl chloride is slowly added dropwise under low temperature stirring. In this reaction, the acid binding agent can neutralize the hydrogen chloride generated by the reaction and promote the positive progress of the reaction. After the dropwise addition is completed, the temperature is raised to an appropriate temperature and the reaction is carried out for several hours. After the reaction is completed, the organic phase is washed with water, separated from the liquid, dried, and then the solvent is removed by distillation under reduced pressure. The crude product is purified by column chromatography and other means to obtain the target product.
Second, o-aminothiophenol can be used to react with p-methylbenzaldehyde. The two are placed in an appropriate solvent such as ethanol, and an appropriate amount of catalyst such as p-toluenesulfonic acid is added to heat the reflux reaction. This reaction accelerates the condensation between the aldehyde group and the amino group to form an imine intermediate, which is then cyclized to form a benzothiazole structure. During the reaction process, the reaction progress can be monitored by thin-layer chromatography. After the reaction is completed, the reaction liquid is cooled, the solids are filtered and collected, and then purified by recrystallization to obtain pure 2- (4-methylphenyl) -benzothiazole.
Another way is to use 2-halobenzothiazole and p-methylphenylboronic acid as raw materials for coupling reaction under palladium catalysis. The reaction system is added with palladium catalysts such as tetra (triphenylphosphine) palladium, ligands, bases and organic solvents, and is protected by inert gases such as nitrogen. First, the system is heated to an appropriate temperature, stirred evenly, and 2-halobenzothiazole and p-methylphenylboronic acid are added, and the reaction continues for several hours. After the reaction is completed, the target product can be obtained by extraction, washing, drying, and column chromatography. This method selectively realizes carbon-carbon bond coupling with the help of palladium catalysis and efficiently synthesizes the target compound.

I have not obtained the exact price range of 2- (4-methylphenyl) -benzothiazole in the market. However, if you want to know the price of this product, you can follow various paths. First, visit the chemical raw material trading platform, which gathers many suppliers and product information, and the prices are often listed on it. Second, consult the chemical product supplier, and you can directly send a letter or interview to ask for the quotation of this product. Different suppliers may have different prices due to differences in raw material costs, production processes, and economies of scale. Third, look at relevant industry reports and information, which may involve the market price analysis of this chemical. Even if it is not real-time, it can also help to speculate on the price trend and range.
The price of chemical products is not constant, and is affected by factors such as fluctuations in raw material prices, market supply and demand trends, and changes in policies and regulations. If the price of raw materials rises, or the production cost rises, the price of the product will also rise; if the market supply exceeds demand, the price may drop. Therefore, in order to obtain the confirmed price of 2- (4-methylphenyl) -benzothiazole, it is necessary to pay attention to market dynamics and inquire and compare in many ways to obtain a more accurate price range.

2-%284-Methylphenyl%29-benzothiazole is 2- (4-methylphenyl) benzothiazole, the manufacturer of this substance, there are many in the world. However, I have searched for ancient books, and it is difficult to list them all.
In the field of Guanfu Chemical, there are various manufacturers specializing in the manufacture of specialty chemicals, often involved in the production of these compounds. Such as Sigma-Aldrich, which is a world-famous chemical reagent supplier with a wide range of stocks, or 2- (4-methylphenyl) benzothiazole for scientific research and industrial needs.
There is also Acros Organics, which is also a leader in the industry and is quite famous for the supply of organic chemical reagents. Its production process is exquisite, and the product quality is high. 2- (4-methylphenyl) benzothiazole may be one of its product lines.
Among domestic manufacturers, such as Shanghai search banner biochemical technology joint stock company, it provides various scientific research reagents as its business, and has made many achievements in the field of organic synthesis reagents, or produces this compound to meet the requirements of the domestic market.
Another example is Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., which relies on advanced technology and strict quality control to establish a foothold in the field of chemical reagent production. 2- (4-methylphenyl) benzothiazole may be within its production range.
However, the chemical market is unpredictable, and the production and waste of manufacturers and the storage and waste of products often change with the times. To know the latest and detailed list of manufacturers, you need to check the chemical professional directory, industry exhibition materials, or consult experts in the chemical field to get the exact information.