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What are the main uses of 2- (4-methoxy-phenyl) -thiazole-4-formaldehyde?
2-%284-%E7%94%B2%E6%B0%A7%E5%9F%BA-%E8%8B%AF%E5%9F%BA%29-%E5%99%BB%E5%94%91-4-%E7%94%B2%E9%86%9B, its main uses are quite extensive.
In terms of military use, this substance can be used to make all kinds of weapons. In ancient battlefields, weapons made from it were used as raw materials. During the battle, the blade was sharp and the edge was cold, which was quite powerful. It was a weapon for soldiers to kill the enemy and had a great impact on the trend of the war.
In the industrial field, it is also a key material. It can be used to forge strong instruments and improve the durability and performance of the equipment. In the process of equipment manufacturing, it lays the foundation like a cornerstone, helping to create more sophisticated and efficient tools and equipment, and greatly improving the efficiency of industrial production.
It also plays an important role in agriculture. Appropriate use can improve soil texture, enhance soil fertility, and create a suitable environment for crop growth, so as to promote the growth of crops, improve harvests, and ensure the basic of people's livelihood - food supply.
In addition, it is also indispensable in many aspects of civilian life. For example, building household appliances for daily use by the people and improving the quality of life. In the construction industry, it can also participate in the construction of a solid building structure to ensure the stability and safety of houses.
In short, 2-%284-%E7%94%B2%E6%B0%A7%E5%9F%BA-%E8%8B%AF%E5%9F%BA%29-%E5%99%BB%E5%94%91-4-%E7%94%B2%E9%86%9B has significant uses in military, industrial, agricultural, and civilian fields, and has a profound impact on social development and people's lives.
What are the physical properties of 2- (4-methoxy-phenyl) -thiazole-4-formaldehyde
4-Ethylheptane is an organic compound with the following physical properties:
It is a liquid under normal conditions. Due to the correlation between the intermolecular forces and the relative molecular mass, 4-ethylheptane has a relatively large molecular mass. The intermolecular van der Waals force makes it liquid at room temperature and pressure. Its boiling point is about 140-160 ° C. With the increase of the number of carbon atoms in the molecule and the increase of the relative molecular mass, the intermolecular force increases, and higher energy is required to overcome the intermolecular attractive force, so the boiling point is higher. < Br > 4-ethylheptane has a low melting point, usually below -50 ° C. The melting point is determined by the degree of time division and intermolecular forces in the solid state of organic compounds. Its molecular structure is relatively loose, and the intermolecular forces are limited, resulting in a low melting point.
The density of this substance is less than that of water, about 0.75-0.85 g/cm ³. Due to the relatively loose structure composed of carbon atoms and hydrogen atoms of hydrocarbon substances, the unit volume mass is less than that of water. It is difficult to dissolve in water because it is a non-polar molecule, and water is a polar molecule. According to the principle of "similar miscibility", non-polar 4-ethylheptane is difficult to dissolve in polar water. However, 4-ethylheptane can be miscible with most organic solvents, such as ethanol, ether, benzene, etc. Because these organic solvents are mostly non-polar or weakly polar, they are similar to the intermolecular force of 4-ethylheptane and can be mixed with each other. In addition, 4-ethylheptane is flammable and burns in sufficient oxygen to generate carbon dioxide and water. Because it is a hydrocarbon and contains carbon and hydrogen, a combustion reaction can occur to release energy.
What is the chemical synthesis method of 2- (4-methoxy-phenyl) -thiazole-4-formaldehyde?
To prepare 2 - (4-methoxy-benzyl) -pyridine-4-formaldehyde and 4-methylquinoline, the chemical synthesis method is as follows.
Preparation of 2 - (4-methoxy-benzyl) -pyridine-4-formaldehyde:
Usually 4-pyridine formaldehyde is used as the starting material. Shilling 4-pyridine formaldehyde and p-methoxy benzyl halide are nucleophilic substitution in an alkaline environment and with the help of a phase transfer catalyst. For example, potassium carbonate is selected as the base, tetrabutylammonium bromide is used as the phase transfer catalyst, and acetonitrile is used as the solvent to heat and stir. In this reaction, the base grabs 4-pyridine formaldehyde α-hydrogen to generate carbon negative ions, which attack the benzyl carbon of methoxy benzyl halide, and the halogen ions leave, so 2- (4-methoxy-benzyl) -pyridine-4-formaldehyde is obtained. After the reaction is completed, the product is purified by extraction, column chromatography, etc.
to produce 4-methylquinoline:
Skraup synthesis is commonly used. Aniline and glycerin are used as raw materials, sulfuric acid is used as dehydrating agent, and arsenic pentoxide or ferric chloride are used as oxidizing agents. During the reaction, glycerol is first dehydrated under the action of sulfuric acid to form acronaldehyde, and aniline is nucleophilic added to it, then cyclized, and then oxidized and aromatized to obtain 4-methylquinoline. The specific operations are as follows: Mix aniline, glycerin, concentrated sulfuric acid and oxidizing agent in proportion, heat and reflux. The reaction is violent, and attention should be paid to temperature control. After the reaction, the product is purified by neutralization, distillation, and recrystallization.
Or it can be reacted by o-aminophenone and ethyl acetoacetate under the action of acidic catalyst to form a ring first, and then de The reaction conditions are relatively mild and the post-treatment is relatively simple.
What is the price range of 2- (4-methoxy-phenyl) -thiazole-4-formaldehyde in the market?
There is a question today: What is the price range of 2 - (4 - methoxy - benzyl) -pyridine - 4 - acetonitrile in the market?
The price of Guanfu's shops often changes due to various reasons, such as the amount of supply, the change of seasons, the situation of supply and demand, the complexity of the process, and even the differences in regions and the policies of merchants.
This 2 - (4 - methoxy - benzyl) -pyridine - 4 - acetonitrile, if the supply is abundant and the supply exceeds the demand, the price may decrease; if the supply is scarce and the demand exceeds the supply, the price will rise. If the preparation technique is simple, the cost can be controlled, and the price can be close to the people; if the process is complicated and time-consuming, the price may be expensive.
If you want to know the price range on the market, you must consult all merchants, chemical material trading offices, or consult people who specialize in the chemical field. I have not seen the detailed market, so it is difficult to determine the exact price. Only those who want to buy are advised to go to the market and visit many places to get an accurate price, so as not to be mistaken by false prices.
What are the storage conditions for 2- (4-methoxy-phenyl) -thiazole-4-formaldehyde?
4-Ethylheptane should be stored in a cool and ventilated place, away from fire and heat sources, and avoid direct sunlight. This substance is a flammable liquid, and its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of open flame and high heat. Therefore, explosion-proof lighting and ventilation facilities should be used in the storage place, and the use of machinery and tools that are prone to sparks is strictly prohibited.
For storage containers, it is necessary to ensure that they are well sealed and cannot leak. They should be stored separately from oxidants, acids, etc., and should not be mixed. At the same time, the storage area should be equipped with suitable materials to contain leaks, and clear warning signs such as "no fireworks" should be set.
When handling, it should be handled lightly to prevent damage to packaging and containers. In the event of a leak, emergency responders need to quickly evacuate the leaked contaminated area to a safe area and isolate it, strictly restricting access. It is recommended that emergency responders wear self-contained positive pressure breathing apparatus and anti-static work clothes. Cut off the source of the leak as much as possible to prevent it from flowing into the restricted space such as sewers and drainage ditches. In the case of a small amount of leakage, it can be adsorbed or absorbed by sand or other non-combustible materials; in the case of a large amount of leakage, it is necessary to build a dike or dig a pit for containment, cover it with foam to reduce steam disasters, and then transfer it to a tanker or a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal. In this way, the safety of 4-ethylheptane during storage can be ensured and accidents can be avoided.