2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

2-% 284-hydroxyphenyl% 29-4-methylthiazole-5-carboxylate, this is an organic compound. It is widely used in the field of medicine and is often used as an intermediate for drug synthesis. The preparation of many drugs requires this as a starting material, which is converted into substances with specific pharmacological activities through a series of chemical reactions, or used to develop antibacterial drugs to inhibit the growth and reproduction of bacteria by interfering with specific physiological processes; or used to create anti-cancer drugs that act on specific targets of cancer cells and hinder their proliferation and diffusion.
In the field of materials science, this compound may participate in the synthesis of polymer materials. Adding this compound can endow the material with unique properties, such as improving the optical properties of the material, making it stand out in the field of optoelectronic devices, which can be used to manufacture Light Emitting Diode, etc.; or enhancing the stability and durability of the material, improving the performance of the material under different environmental conditions.
In the agricultural field, it can be used as a synthetic raw material for pesticides or plant growth regulators. As a pesticide, it can play a role in targeting specific diseases and insect pests to ensure the healthy growth of crops; as a plant growth regulator, it can regulate the growth and development process of plants, such as promoting seed germination, increasing crop yield, and improving fruit quality.
In the field of scientific research, due to its unique chemical structure, it is often used by researchers to explore the mechanism of organic reactions, help to deeply understand the essence of chemical reactions, and provide theoretical support and practical basis for the development of organic synthetic chemistry.

2-% (4-hydroxyphenyl) -4-methylthiazole-5-carboxylate is an organic compound. Its physical properties are quite important, and it is related to the behavior of this compound in various situations.
When it comes to appearance, it is often in the shape of a solid state or a crystalline form, which is due to the interaction between molecules, resulting in the formation of a regular lattice structure. Looking at its color, it is mostly white or off-white. This pure appearance is due to the uniformity of its molecular structure.
The melting point is also a key physical property. Usually, this compound has a specific melting point range due to intermolecular forces. When heated to a specific temperature, the molecule is energized enough to overcome the lattice energy, the lattice structure disintegrates, and the substance then changes from solid to liquid. The exact value of this melting point is an important basis for identifying this compound, and it is related to the size, shape and strength of the intermolecular forces of the molecule.
Solubility should not be ignored. In common organic solvents, their solubility varies. In polar organic solvents, such as ethanol and methanol, it may have a certain solubility. Because the molecule contains polar groups such as hydroxyl groups, it can form hydrogen bonds and other interactions with polar solvent molecules. However, in non-polar organic solvents, such as n-hexane and benzene, the solubility may be poor, because the overall polarity of the molecule is incompatible with non-polar solvents. The density of
is also one of the physical properties of the compound. Its density value reflects the compactness of the molecular packing, which is related to the molecular size, structure and crystal form. By measuring the density, it can help to understand its distribution in the mixture.
In addition, the volatility of this compound is low. Due to the relatively strong intermolecular forces, the molecules are not easy to escape from the liquid or solid surface. This property has a significant impact on storage and application, which can ensure its stability.
In summary, the physical properties of 2% (4-hydroxyphenyl) -4-methylthiazole-5-carboxylate, such as appearance, melting point, solubility, density, and volatility, are important for the understanding and application of this compound.

To prepare 2 - (4 - hydroxyphenyl) - 4 - methylthiazole - 5 - carboxylate, the method is as follows:
First prepare 4 - hydroxyacetophenone, thioacetamide and ethyl bromoacetate and other raw materials. Dissolve 4 - hydroxyacetophenone and thioacetamide in a suitable solvent, such as ethanol or dimethylformamide. Then add an appropriate amount of base, such as potassium carbonate or sodium carbonate, to promote the reaction. The mixture needs to be stirred and heated at a moderate temperature, such as 60 to 80 degrees Celsius, so that the two can be condensed first to obtain 2 - (4 - hydroxyphenyl) - 4 - methylthiazole. Then, the obtained 2 - (4 - hydroxyphenyl) - 4 - methylthiazole is reacted with ethyl bromoacetate in another reaction system in the presence of a similar solvent and base. The reaction temperature may need to be adjusted to 80 to 100 degrees Celsius, and the stirring is continued for several hours. The substitution reaction of thiazole position 5 with ethyl bromoacetate results in 2 - (4 - hydroxyphenyl) - 4 - methylthiazole - 5 - ethyl carboxylate. Finally, hydrolysis of 2 - (4 - hydroxyphenyl) - 4 - methylthiazole - 5 - ethyl carboxylate is carried out in an aqueous solution of sodium hydroxide or potassium hydroxide. The hydrolysis temperature is about 40 to 60 degrees Celsius. After a certain period of time, 2 - (4 - hydroxyphenyl) - 4 - methylthiazole - 5 - carboxylate can be obtained. After the reaction, the product is purified by methods such as extraction, crystallization, and recrystallization to obtain a high-purity product.

Today's question, what is the price of 2- (4-hydroxyphenyl) -4-methylthiazole-5-carboxylate in the market? This is a fine chemical, and its price varies depending on quality, purity, and supply and demand. If it is of ordinary purity, the price in the market may range from tens to hundreds of yuan per gram. However, if its purity exceeds 98%, it can be used as a high-end pharmaceutical synthetic raw material, and the price may rise to hundreds of yuan per gram, or even over a thousand yuan.
Looking at the past market conditions, when the market demand for this product is strong and the supply is slightly tight, its price often tends to rise. If the previous year, due to the maintenance of several main producers' devices, the supply volume was reduced, and the price also rose, and the price per gram of some high-purity products exceeded 1,000 yuan.
If the purity is slightly lower, it is used as a general chemical intermediate, and the price may be tens of yuan per gram due to competition. And the prices charged by different merchants are also different. Large merchants may be slightly cheaper due to the benefits of scale; small merchants may be slightly cheaper for profit. In short, to know the exact price, you need to consult all merchants and compare their quotations before you can get it.

2-% 284-hydroxyphenyl% 29-4-methylthiazole-5-carboxylate is one of the organic compounds. It is widely used in medicine, agriculture and materials science.
In the field of medicine, such compounds are often key intermediates for the development of new drugs. Because of their unique molecular structure or biological activity, they can act on specific biological targets in the human body. Or can regulate the physiological processes of cells, such as participating in the catalytic reaction of enzymes and the binding of receptors, etc., which are of great benefit to the treatment of diseases. For example, for specific inflammatory diseases, drugs developed on the basis of them may inhibit the release of inflammatory factors and relieve inflammatory symptoms. < Br >
In the field of agriculture, it also has important applications. It can be used as a plant growth regulator to affect the growth and development of plants. It can promote the growth of plant roots, enhance the ability of plants to absorb nutrients, and improve plant stress resistance, such as drought resistance, pest resistance, etc. It can also be used as an active ingredient of a new type of pesticide. With its special chemical properties, it has inhibitory or killing effects on pests and bacteria, and is more environmentally friendly than traditional pesticides.
In the field of materials science, 2-% 284-hydroxyphenyl% 29-4-methylthiazole-5-carboxylate can be used to prepare materials with special properties. Because of its stable chemical structure, it may enhance the stability and durability of materials. Or it can participate in the synthesis of polymer materials, endowing the materials with new properties, such as improving the optical and electrical properties of the materials, and has potential application value in electronic devices, optical materials, etc.