2-(4-BROMO-PHENYL)-THIAZOLE

2-% 284 - BROMO - PHENYL% 29 - THIAZOLE, that is, 2 - (4 - bromophenyl) thiazole, this substance has a wide range of uses and is a key intermediate in the field of pharmaceutical synthesis. Looking at past books, it is often an indispensable quality in the creation of new drugs. Due to its specific structure, it has good biological activity and pharmacological properties, and can interact with many targets in organisms, helping to develop antibacterial, anti-inflammatory, anti-tumor and other new drugs.
In the field of materials science, it has also emerged. Although ancient books did not describe materials science in detail, it can participate in the preparation of special functional materials in today's eyes. For example, organic optoelectronic materials, with their unique molecular structure, endow materials with special optical and electrical properties, which contribute to the improvement of materials such as display screens and optoelectronic devices.
In the field of chemical research, it is an important model compound. Chemists use it to explore reaction mechanisms and optimize synthesis paths, and many organic synthesis techniques have been refined through their research. Although ancient books do not have as detailed principles as modern chemistry, the basic research of chemistry is in the same vein. The exploration of material reactions in the past is just like the beginning of deepening chemical understanding with 2 - (4-bromophenyl) thiazole today.

2-% 284 - BROMO - PHENYL% 29 - THIAZOLE, in Chinese, is 2 - (4 - bromophenyl) thiazole. This substance has many physical properties.
Looking at its appearance, it is often white to light yellow crystalline powder at room temperature and pressure. This state is easy to observe and handle. In many experiments and industrial processes, powdered substances are easier to disperse and mix.
The melting point is about 138-142 ° C. The melting point is an important physical property of the substance, and this temperature range can help to identify this compound. If the melting point of an unknown substance is measured in this range in the experiment, it can be preliminarily speculated that it may be 2- (4-bromophenyl) thiazole, or contains this component.
Its solubility is also worthy of attention. Slightly soluble in water, but soluble in some organic solvents, such as dichloromethane, chloroform, ethanol, etc. This difference in solubility is due to the molecular structure. Its molecules contain benzene rings and thiazole rings, which have certain hydrophobicity, so it is difficult to dissolve in water with strong polarity; while the polarity of organic solvents is adapted to molecules, so that they can be dissolved in them. This solubility property is crucial for the separation, purification of compounds and the selection of reaction solvents. Choosing the right solvent can increase the contact opportunity of the reactants and improve the reaction efficiency
As for the density, although there is no exact general value, it is deduced according to its structure and the properties of similar compounds, and the density may be slightly higher than that of water. Due to the close arrangement of atoms in the molecule, containing bromine atoms, the relative mass of bromine atoms is large, resulting in an increase in the overall mass. If the volume change is not large, the density will increase. This density characteristic needs to be considered when involving operations such as phase separation, which affects its distribution in the system.
The physical properties of 2 - (4-bromophenyl) thiazole are of critical significance in chemical research, drug synthesis, and materials science, helping researchers better control their behavior and applications.

To prepare 2 - (4 - bromophenyl) thiazole, there are two common methods. One is to use 4 - bromoacetophenone and thioformamide as raw materials. First, 4 - bromoacetophenone is placed in a suitable reaction vessel, and thioformamide is added in the appropriate proportion. Then, under the conditions of suitable temperature and catalyst, the two are condensed. This process requires close attention to changes in temperature. If the temperature is too high or too low, the reaction effect will be affected. After condensation reaction, the crude product of 2 - (4 - bromophenyl) thiazole can be obtained. After purification by means such as recrystallization and column chromatography, high-purity products can be obtained.
The second method is to use 4-bromobenzaldehyde and mercaptoacetamide as the starting materials. First, 4-bromobenzaldehyde and mercaptoacetamide are mixed in a specific solvent, and an appropriate amount of catalyst is added. The reaction needs to be carried out at a specific temperature and time. During this reaction process, the two will gradually react to form an intermediate product, and the intermediate product will be further converted to finally obtain 2- (4-bromophenyl) thiazole. After the reaction is completed, the same separation and purification steps are required to remove impurities and improve the purity of the product. These two methods have their own advantages and disadvantages. In actual operation, the most suitable synthesis path should be selected according to the availability of raw materials, cost and product purity requirements.

Today, there are 2 - (4 - bromo - phenyl) - thiazole, which is difficult to determine the price range in the market. The price depends on many factors.
First, the cost of production is the main reason. The price of raw materials, if 4 - bromobenzene and the materials used in the synthesis of thiazole ring, the fluctuation of the price is directly related to the cost of the product. If the raw materials are scarce, or the preparation is difficult, the price will rise. And the synthesis process, if the steps are cumbersome and the yield is low, the energy consumption and manpower required are also large, the cost increases accordingly, and the price in the market is also high.
Second, the situation of supply and demand is also heavy. If in the fields of medicine, chemical industry, the demand for 2 - (4 - bromo - phenyl) - thiazole is strong, but the supply is limited, the price will rise. On the contrary, if the supply exceeds the demand, the merchants will sell their goods, or reduce the price in order to sell quickly.
Third, the state of market competition has an impact. If there are many producers of this product, the merchants will compete for the market share, or will compete on price, resulting in price fluctuations.
Fourth, the difference between regions cannot be ignored. In different places, the price may be different due to differences in logistics, taxation, and market environment. In places with convenient transportation and mature markets, the price may be relatively flat due to competition; in remote places with underdeveloped markets, the price may be higher due to logistics costs.
With common sense, the price may range from a few yuan to several hundred yuan per gram. However, this is only a rough estimate, and the actual price depends on the specific time, place and market conditions.

2-% 284 - BROMO - PHENYL% 29 - THIAZOLE, Chinese name or 2 - (4 - bromophenyl) thiazole. The storage conditions of this compound are quite important.
Its properties may be sensitive to light, heat, moisture and other factors. Therefore, when storing, it should be stored in a cool and dry place, protected from light. In a cool place, the temperature should not be too high to avoid changes in its properties due to heat, or to trigger chemical reactions that damage its quality. In a dry environment, it can avoid moisture intrusion, prevent it from being hydrolyzed by moisture, and reduce its purity. < Br >
and should be placed in a closed container to prevent contact with components in the air, such as oxygen, carbon dioxide, etc., oxidation, carbonation and other reactions occur. At the same time, it is necessary to keep away from fire and heat sources, because they may be flammable or heat sensitive, in case of fire or high temperature, it may be dangerous, cause material loss, and even endanger safety.
The place where it is stored should also be clearly marked to prevent misuse, and it is advisable to check regularly to see if its properties have changed. If there is any abnormality, it will be dealt with in time to ensure that the quality and utility of 2 - (4-bromophenyl) thiazole are consistent. Such storage is comprehensive and can be stored for a long time without changing its properties.