2-(4-aminophenyl)-6-methylbenzothiazole double acid

2-% (4-aminophenyl) -6-methylbenzothiazolic acid, this substance is widely used. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize compounds with specific biological activities. The structure of benzothiazole and the characteristics of amino and carboxyl groups make the synthesized drugs have good pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other effects.
In the field of materials science, this substance can participate in the synthesis of polymer materials. With its special structure, it can endow materials with unique properties, such as improving material thermal stability, mechanical properties, etc. For example, when preparing special engineering plastics, the introduction of this diacid structure may improve the heat resistance and wear resistance of plastics, so that they can still maintain good performance in harsh environments such as high temperature and high friction.
Furthermore, in the field of organic synthetic chemistry, it is often used as a building block for building complex organic molecules. Due to its unique functional group and benzothiazole skeleton, chemists can modify and expand it according to specific reaction mechanisms to construct organic compounds with novel structures and specific functions, which contribute to the development of organic synthetic chemistry and promote the research and development process of new organic materials and drug lead compounds.

2-%284-aminophenyl%29-6-methylbenzothiazole double acid, its chemical properties are quite unique. This compound contains the core structure of benzothiazole, which endows it with certain thermal and chemical stability. Under high temperature or specific chemical environment, it is not easy to decompose or undergo significant chemical changes.
From the perspective of acid-base properties, as a double acid, it has acidic characteristics and can neutralize with bases to generate corresponding salts and water. It can react with strong bases such as sodium hydroxide according to stoichiometric ratios, showing its acidic functional group activity.
Its amino-containing and benzene-ring structure endows the compound with certain nucleophilic properties. The nitrogen atom in the amino group has a lone pair of electrons, which can be used as a nucleophilic reagent to react with electrophilic reagents, such as nucleophilic substitution reaction with halogenated hydrocarbons, generating new nitrogen-containing derivatives and expanding their chemical transformation pathways.
In addition, the conjugate system exists in the structure of benzothiazole and benzene ring, which affects the electron cloud distribution and spectral properties of the compound. In the ultraviolet-visible spectral region, the electron transition of the conjugate system presents a specific absorption peak, which provides a spectral basis for its analysis and identification. The spatial arrangement and interaction of different groups in the
molecule determine its stereochemical properties. These spatial factors affect the intermolecular interactions, and in the crystal structure or solution, affect the aggregate state and physical properties of the compound, such as solubility, melting point, etc. This 2-%284-aminophenyl%29-6-methylbenzothiazole rich in double acid chemical properties, laying the foundation for its application in materials science, medicinal chemistry and other fields.

To prepare 2- (4-aminophenyl) -6-methylbenzothiazolic acid, the following ancient method can be followed.
First take an appropriate amount of 6-methylbenzothiazole as the starting material and place it in a clean reactor. Then, slowly add an appropriate amount of fuming sulfuric acid to the kettle. This step needs to be handled with caution because it is highly corrosive. Under low temperature and sufficient stirring conditions, the two can fully react. This process requires close attention to temperature changes to ensure that the reaction proceeds smoothly to obtain 6-methylbenzothiazole-2-sulfonic acid intermediate.
Next, the obtained intermediate is mixed with p-nitroaniline in a specific ratio, and then an appropriate amount of basic catalyst, such as sodium carbonate, is added. In an environment of heating and continuous stirring, the condensation reaction occurs. During this reaction process, the control of temperature is crucial, and it should be maintained at an appropriate range to promote the smooth progress of the reaction to generate 2 - (4-nitrophenyl) -6-methylbenzothiazole.
Then, move 2- (4-nitrophenyl) -6-methylbenzothiazole to another reaction device, add an appropriate amount of reducing agent, such as the combination of iron powder and hydrochloric acid, or use catalytic hydrogenation to reduce the nitro group to an amino group, resulting in 2- (4-aminophenyl) -6-methylbenzothiazole.
Finally, react 2- (4-aminophenyl) -6-methylbenzothiazole with an appropriate amount of strong oxidants, such as potassium permanganate or potassium dichromate, in an acidic medium. During the reaction, the reaction conditions, such as temperature and reaction time, need to be strictly controlled. After this oxidation step, the methyl group on the benzene ring is oxidized to the carboxyl group, and the final product is 2- (4-aminophenyl) -6-methylbenzothiazolic acid.
After each step of the reaction, suitable separation and purification methods, such as crystallization, extraction, column chromatography, etc., are required to ensure the purity of the product and provide high-quality raw materials for the next reaction, so that the target product can be successfully prepared.

I have not obtained "2- (4 -aminophenyl) -6 -methylbenzothiazole diacid" on the market to confirm the price, covering this substance or involving a specific chemical industry, scientific research field, its price often varies depending on quality, purity, supply and demand and the seller.
If you ask for its price, you can take the following ways: First, ask chemical raw material suppliers, many chemical supplier websites or have this product, its listed price or reference. Second, visit the scientific research reagent sales platform, because scientific research reagents or containing this compound, its price may also be shown. Third, in contact with chemical research institutions, they may often buy this product to know its approximate price range. < Br >
However, the price range is difficult to determine. Those with high purity will have a higher price than ordinary products. When supply and demand are tight, the price will also rise. Therefore, if you want to know the exact price, you should explore it from various channels to get a near-real price.

I don't know the specific geometry of the manufacturer of 2- (4-aminophenyl) -6-methylbenzothiazole diacid. However, the field of chemical industry is vast, and the manufacturers who want this diacid can be explored from many ways.
In today's world, chemical industry information mostly exists on online platforms. You can borrow a special chemical website, which often lists a lot of chemical products and manufacturer information. There is also a business platform, which brings together merchants from all walks of life, or you can get clues from relevant manufacturers.
Furthermore, the chemical exhibition is also a way. During the exhibition, chemical companies display their products more, and you may meet those who produce this diacid here. < Br >
In addition, professional journals and magazines in the chemical industry often contain company information and product introductions. Read such publications carefully, or you can get something.
Although I can't identify the specific manufacturer, we can find the desired manufacturer in this way to solve the confusion of the manufacturer of 2 - (4-aminophenyl) -6-methylbenzothiazolic acid.