2 4 Aminophenyl 6 Methylbenzothiazole 7 Sulfonic Acid
quinoline thiophene imidazole thiazole

2-(4-aminophenyl)-6-methylbenzothiazole-7-sulfonic acid

    Specifications

    HS Code

    461062

    Chemical Formula C14H12N2O3S2
    Molecular Weight 320.39 g/mol
    Appearance Solid (usually powder)
    Solubility In Water Limited solubility (sulfonic acid group provides some hydrophilicity but organic part restricts it)
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF due to the combination of polar and non - polar groups
    Pka Sulfonic Acid Group Typically around 0 - 2 (sulfonic acids are strong acids)
    Uv Vis Absorption Absorption bands related to aromatic rings in the UV region, around 250 - 350 nm
    Ir Absorption Characteristic peaks for C - H stretching in aromatic rings, S = O stretching of sulfonic acid group, C - N stretching in the benzothiazole and amino - phenyl parts

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    General Information
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    Frequently Asked Questions

    As a leading 2-(4-aminophenyl)-6-methylbenzothiazole-7-sulfonic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid?
    2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid, its chemical structure is quite unique. This compound contains the core structure of benzothiazole, which is formed by fusing the benzene ring and the thiazole ring. It is like a carefully constructed pavilion, with a stable structure and unique chemical properties.
    In the second position of the benzothiazole ring, there is a 4-aminophenyl group connected. This aminophenyl group is like an outstretched arm, giving the compound specific reactivity and electronic properties. Amino-NH2O has the property of electrons, which can affect the distribution of the electron cloud of the molecule, change the chemical bonds around it and the chemical behavior of the whole molecule, and play a key role in many chemical reactions.
    Furthermore, at position 6, there is methyl-CH
    . The introduction of methyl groups, although seemingly minor changes, has a profound impact on the spatial structure and physicochemical properties of the molecule. It changes the three-dimensional configuration of the molecule, affects the interaction forces between molecules, such as van der Waals forces, etc., and then affects the melting point, boiling point, solubility and other properties of the compound.
    At position 7, there is a sulfonic acid group -SO
    H. The sulfonic acid group is a strong polar group with strong hydrophilicity, which significantly enhances the solubility of the compound in water. And its acidic properties enable the compound to exhibit acidic-related chemical reactions under specific conditions, such as neutralization with bases.
    In summary, the chemical structure of 2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid is composed of benzothiazole core, with 2-aminophenyl group, 6-methyl group and 7-sulfonic acid group. The parts cooperate with each other, giving the compound unique and rich chemical properties and potential application value.
    What are the main uses of 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid?
    2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid is 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid, which has a wide range of uses. In the field of dyes, it is often the key raw material for the synthesis of new dyes. Because of its specific molecular structure and functional groups, it can be cleverly designed and reacted to produce bright and bright dyes with good fastness. It is widely used in textiles, printing and dyeing industries, giving fabrics brilliant color and lasting non-fading.
    In the field of pharmaceutical research and development, this compound may have potential biological activity. By studying its interaction with specific targets in organisms, researchers explore the possibility of developing new drugs, providing new opportunities for overcoming diseases.
    In the field of materials science, it can be used as a synthetic component of functional materials. By introducing this substance, it can endow materials with special properties such as optics and electricity, and expand the application of materials in optical devices, sensors and other fields.
    In addition, in the field of chemical analysis, due to its unique chemical properties, it may be used for the detection and analysis of certain substances, providing new means for the development of chemical analysis methods. In short, 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid has shown important application value in many fields, promoting technological progress and innovation in various related fields.
    What are the physical properties of 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid?
    2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid is 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid. The physical properties of this compound are particularly important, which is related to its application in many fields.
    Its appearance is often solid, but the specific morphology may vary depending on the preparation method and purity. Or it is a crystalline powder with fine texture and well-proportioned particles. Its color is usually close to white to light yellow, and the higher the purity, the lighter the color.
    When it comes to solubility, this compound exhibits a certain solubility in water. However, its degree of solubility is not unlimited, and it can be partially dissolved in water at room temperature to form a uniform solution. In organic solvents, such as ethanol, acetone, etc., there is also a certain solubility. In ethanol, under appropriate temperature and stirring conditions, it can be well dissolved, which makes it important in organic synthesis and preparation.
    Melting point is a key parameter characterizing its physical properties. 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid has a specific melting point range, and this melting point value can be accurately determined by thermal analysis. Knowing the melting point helps to judge its purity. For those with high purity, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point may be offset and the range will be wider.
    Furthermore, its density is also an important physical property. Density reflects the mass of a substance per unit volume, which is of great significance for the preparation process, separation and purification. When determining its storage, transportation and use mode, density considerations are indispensable.
    In addition, the hygroscopicity of this compound cannot be ignored. In a humid environment, it may absorb moisture in the air, causing changes in its physical form and chemical stability. Therefore, when storing, a dry environment should be selected to maintain its quality.
    The physical properties of 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid, such as appearance, solubility, melting point, density and hygroscopicity, are interrelated and affect its application and treatment in chemical, pharmaceutical and other fields. In-depth investigation and familiarity with these properties are essential for the rational use and further study of this compound.
    What are the synthesis methods of 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid?
    2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid is 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid, and its synthesis method is as follows:
    The starting material can be selected from 4-aminobenzoic acid and o-methylthiophenol, etc.
    First, 4-aminobenzoic acid is reacted with appropriate reagents to activate its carboxyl group, such as with dichlorosulfoxide to convert to acid chloride. Subsequently, the acid chloride undergoes a nucleophilic substitution reaction with o-methylthiophenol in the presence of a suitable base (such as triethylamine, etc.) to form a sulfur-containing intermediate.
    Next, the intermediate undergoes a cyclization reaction under appropriate conditions to construct a benzothiazole ring. The cyclization process may require heating as well as specific catalysts, such as certain Lewis acids, etc., to promote intramolecular cyclization to produce 2- (4-aminophenyl) -6-methylbenzothiazole.
    Finally, a sulfonation reaction is performed on the resulting benzothiazole product to introduce a 7-sulfonic acid group. The sulfonation reaction can usually be carried out using sulfonating reagents such as concentrated sulfuric acid or fuming sulfuric acid and reacted at an appropriate temperature. After the reaction is completed, a series of post-processing operations such as neutralization, extraction, recrystallization, etc. are performed to obtain a pure 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid product. < Br >
    It is necessary to pay attention to the control of the conditions of each step of the reaction, including temperature, reaction time, reagent dosage, etc., to ensure the smooth progress of the reaction and the purity and yield of the product.
    2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid What are the precautions during use?
    2-%284-aminophenyl%29-6-methylbenzothiazole-7-sulfonic acid is 2- (4-aminophenyl) -6-methylbenzothiazole-7-sulfonic acid, which is an organic compound. During use, be sure to pay attention to the following things:
    First, safety protection is essential. This compound may have certain toxicity and irritation. When contacting, be fully armed, wear protective clothing, gloves and protective glasses, etc., to avoid direct contact with the skin and eyes. If inadvertently contacted, rinse with plenty of water immediately, and seek medical consultation according to the actual situation.
    Second, chemical stability cannot be ignored. It is necessary to understand its chemical properties in detail to avoid coexistence with substances that may react. When storing, it should be placed in a dry, cool and well-ventilated place, away from fire sources and oxidants, etc., to prevent dangerous reactions.
    Third, the operating specifications must be strictly adhered to. When using the compound, use appropriate equipment and methods to follow precise operating procedures. Weighing should be accurate, and operations such as configuring solutions should be carried out under suitable environments and conditions to ensure the accuracy and reliability of experimental or production results.
    Fourth, waste disposal should be treated with caution. After the experiment or use is completed, the remaining compound and related waste must not be discarded at will. Proper disposal should be carried out in accordance with relevant regulations and environmental protection requirements to prevent pollution to the environment. Fifth, if it involves industrial production or large-scale use, it is also necessary to fully consider its impact on production equipment, such as whether it will corrode the equipment, and then select appropriate materials and protective measures to ensure the smooth operation of production.