2-[3-(pyrrolidin-1-ylsulfonyl)phenyl]-1,3-benzothiazole

2-%5B3-%28pyrrolidin-1-ylsulfonyl%29phenyl%5D-1%2C3-benzothiazole is an organic compound. Its chemical structure consists of a main nucleus of benzothiazole, which is connected with a substituent-containing phenyl group at position 2 of the main nucleus. Specifically, the third position of the phenyl group is connected with a pyrrolidine-1-ylsulfonyl group.
The main nucleus of benzothiazole is fused from a benzene ring and a thiazole ring, and has a special conjugate structure, so that the compound may have specific physical and chemical properties. 3- (pyrrolidine-1 -ylsulfonyl) phenyl is used as a substituent, pyrrolidine is a nitrogen-containing five-membered heterocyclic ring, which has certain basic and nucleophilic properties; sulfonyl has electron-withdrawing effect, or affects the electron cloud distribution, polarity and reactivity of the compound.
This substituent is chemically bonded to the main nucleus of benzothiazole, and together form 2-%5B3-%28pyrrolidin-1-ylsulfonyl%29phenyl%5D-1%2C3-benzothiazole unique chemical structure, which determines its specific reactivity and biological activity in organic synthesis, pharmaceutical chemistry and other fields.

2-%5B3-%28pyrrolidin-1-ylsulfonyl%29phenyl%5D-1%2C3-benzothiazole, this compound has important uses in many fields.
In the field of pharmaceutical research and development, it may have unique biological activities or interact with specific biological targets. For example, it may be used as a potential anti-tumor drug, inhibiting the proliferation and spread of cancer cells by regulating key signaling pathways in cancer cells. Or in the treatment of neurological diseases, it affects the metabolism and transmission of neurotransmitters, providing new ideas and directions for the treatment of Parkinson's disease, Alzheimer's disease and other diseases.
In the field of materials science, its structural properties may make it stand out in the field of organic optoelectronic materials. It can be used as a luminescent material for organic Light Emitting Diode (OLED). With its unique molecular structure, it can achieve efficient electroluminescence and improve the brightness and color saturation of display devices. In terms of sensor materials, it exhibits a selective response to specific substances and realizes sensitive detection of harmful gases, biomolecules, etc. in the environment.
In the agricultural field, or can be used as an active ingredient of new pesticides. By interfering with specific physiological processes of pests and pathogens, it plays an efficient role in insecticidal and bactericidal effects, and is less toxic and environmentally friendly than traditional pesticides, contributing to the sustainable development of agriculture.

To prepare 2- [3- (pyrrolidine-1-ylsulfonyl) phenyl] -1,3-benzothiazole, there are several common methods.
First, you can start from a suitable benzothiazole derivative. Take the benzothiazole containing a specific substituent and react it with the reagent containing pyrrolidine-1-ylsulfonyl. This reaction requires a suitable catalyst and is carried out in a suitable temperature and solvent environment. For example, with a base as a catalyst, in a polar organic solvent such as N, N-dimethylformamide, heating prompts a nucleophilic substitution reaction between the two, so that the pyrrolidine-1-ylsulfonyl group is successfully connected to the specific position of the benzene ring of benzothiazole.
Second, you can also start with the construction of the benzothiazole ring. Thioamide compounds containing 3- (pyrrolidine-1-ylsulfonyl) phenyl groups and o-halogenated anilines are used as raw materials. Under basic conditions, the two first condensate, and then cyclize to form a benzothiazole structure. In this process, the strength of the base, reaction time and temperature all have a great influence on the reaction process and yield. Fine regulation is required to obtain the target product with higher yield.
Third, the coupling reaction catalyzed by transition metals can also be considered. For example, using halobenzothiazole and borate esters or boric acids containing pyrrolidine-1-yl sulfonyl groups as substrates, under the action of transition metal (such as palladium, etc.) catalysts and ligands, the coupling of carbon-carbon bonds or carbon-hetero bonds is achieved, so as to obtain the target product. This method requires strict reaction conditions, and the selection of catalysts and ligands is also crucial, which requires comprehensive consideration to achieve the best reaction effect.

2-%5B3-%28pyrrolidin-1-ylsulfonyl%29phenyl%5D-1%2C3-benzothiazole is an organic compound. Its physical and chemical properties are unique and relate to many aspects of this compound.
Looking at its appearance, it is mostly solid at room temperature and pressure, or powdery, delicate and has a specific color, usually between white and light yellow. This color is derived from the arrangement of atoms and the distribution of electron clouds in the molecular structure, which affects the absorption and reflection of light.
In terms of melting point, due to intermolecular forces, such as van der Waals force, hydrogen bonds, etc., the compound has a specific melting point range. After experimental determination, it is roughly in a certain range. This melting point is the inherent characteristic of the compound and can be used for purity determination and material identification.
In terms of solubility, according to the principle of similar miscibility, it has good solubility in organic solvents such as dichloromethane and chloroform. Because its molecular structure contains groups similar to those of organic solvents, the interaction between molecules is conducive to dissolution. However, the solubility in water is poor, because the polarity of water molecules is very different from the molecular structure of the compound, and the interaction force between each other is weak.
Stability is also an important property. It is relatively stable under normal conditions. When exposed to high temperature, strong acid, strong base or strong oxidant, the chemical bonds in the molecular structure may be affected to cause a reaction. For example, when the temperature is high, some chemical bonds in the molecule vibrate intensified, which may break and initiate a decomposition reaction; when strong acid and strong base exist, atoms such as nitrogen and sulfur in the molecule or react with them, changing the structure and properties of the
This compound has potential application value in materials science, medicinal chemistry and other fields due to its specific physical and chemical properties. Scientists can develop new materials and explore new drugs according to its properties.

2-%5B3-%28pyrrolidin-1-ylsulfonyl%29phenyl%5D-1%2C3-benzothiazole is an organic compound that is emerging in today's chemical and materials fields and has great application prospects.
In the field of pharmaceutical research and development, this compound shows certain affinity and activity to specific biological targets due to its unique structure. Or it can be used as a lead compound, chemically modified and optimized to develop new drugs to deal with some difficult diseases, such as some chronic diseases or rare diseases, which is expected to bring new therapeutic opportunities to patients.
In the field of materials science, it can participate in the creation of high-performance materials by virtue of its own characteristics. For example, by incorporating polymer materials, it may be possible to improve the physical properties of materials, such as enhancing the stability of materials and improving their weather resistance, thereby expanding the application of materials in high-end fields such as aerospace and automobile manufacturing, and helping to improve the performance of related industries.
Furthermore, in the field of fine chemicals, this compound may be used as a key intermediate to derive a series of high-value-added fine chemicals, which are widely used in coatings, dyes and other industries, providing new raw material options for product innovation and upgrading in these industries.
Although this compound has not yet been widely used on a large scale, with the deepening of scientific research and the advancement of technology, it will surely shine in many fields over time, injecting new impetus into the development of various industries and bringing new changes.