2-[3-Cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-Thiazole Carboxylic Acid Ethyl Ester

This is the naming of an organic compound. In order to clarify its chemical structure, it is necessary to analyze it according to the naming rules of organic chemistry. "2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-5-thiazole carboxylic acid ethyl ester", "thiazole" is a five-membered heterocyclic parent nucleus containing nitrogen and sulfur. In the second position of the thiazole ring, there is a phenyl group containing a specific substituent. The third position of this phenyl group has a cyano group (-CN), and the fourth position is connected with a 2-methylpropoxy group (- (CH -2) - O - CH (CH) ²). The thiazole ring has methyl (-CH < unk >) at the 4th position, and carboxylate ethyl (-COOCH < unk > CH < unk >) at the 5th position. Its structure is as follows: With the thiazole ring as the core, each substituent is connected in an ordered order according to a given position to form an organic molecule with a specific spatial configuration and chemical activity. This structure determines the physical and chemical properties of the compound, and may have specific uses and reactivity in the fields of organic synthesis, medicinal chemistry, etc.

2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-5-thiazole carboxylic acid ethyl ester, this is an organic compound. Its physical properties are related to the external performance of the substance, and are of great significance for understanding the behavior and application of the compound under specific conditions.
Looking at its appearance, it is mostly white to off-white crystalline powder at room temperature and pressure. This form is easy to store, transport and access. In many chemical processes, crystalline powder is easy to measure and mix, laying a good foundation for subsequent reactions.
The melting point is about a specific temperature range, which reflects the strength of intermolecular forces. The determination of the melting point is crucial in the identification of the purity of compounds and the study of phase transitions. If the melting point deviates from the established range, or implies that the compound contains impurities, its quality and performance will be affected.
Solubility is also an important physical property. In organic solvents such as ethanol and dichloromethane, the compound exhibits some solubility, but poor solubility in water. This property needs to be taken into account when separating, purifying and preparing compounds. Organic solvents have good solubility, which is conducive to extraction, recrystallization and other operations; poor solubility in water indicates that when it comes to the reaction or application of aqueous phase systems, special designs are required to achieve its dispersion or dissolution.
In addition, density is also one of its physical properties. Although there is no exact value, density is related to the quality and volume of the compound. When designing material storage and transportation equipment in chemical production, this factor needs to be taken into account to ensure that the equipment specifications are suitable and the production is safe and efficient.
In summary, the physical properties of 2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-5-thiazole carboxylic acid ethyl ester, such as appearance, melting point, solubility and density, are indispensable factors in the research and application of chemical, pharmaceutical and other fields. In-depth understanding of it will help to use this compound better.

2-% 5B3-cyano-4-% 282-methylpropoxy% 29 phenyl% 5D-4-methyl-5-thiazole carboxylic acid ethyl ester, this is an organic compound. Although its main use is not directly described in such books as Tiangong Kaiwu, it can be discussed from multiple ends based on current chemical knowledge and chemical application views.
In the field of medicinal chemistry, such compounds containing thiazole structures often have potential biological activities. or can provide key intermediates for the development of new drugs. Due to the special structure of the thiazole ring, it is possible to interact with specific targets in the organism, such as the inhibition of certain enzymes or the regulation of receptors, which is expected to develop therapeutic drugs for specific diseases, such as antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of materials science, this compound may play a role in the preparation of special functional materials due to its unique molecular structure. For example, after rational molecular design and modification, it can be used to prepare materials with special optical and electrical properties, which can be used in organic Light Emitting Diode (OLED), sensors and other fields. Functional groups such as cyano and ester groups in its molecules can affect the physical and chemical properties of materials and provide opportunities for material performance regulation.
In agricultural chemistry, some compounds containing similar structures exhibit insecticidal and bactericidal activities. This compound may also have the potential to be developed as a new type of pesticide, helping to control crop diseases and insect pests, improve agricultural production efficiency, and ensure food security.
Although this specific compound is not mentioned in "Tiangong Kaiwu", it is based on the creation and application wisdom contained in ancient scientific and technological works. It can be seen that such compounds have important potential uses in many fields such as current chemical industry, medicine, materials, agriculture, etc., and can provide key assistance for the development and innovation of various industries.

The method of preparing 2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-5-thiazole carboxylic acid ethyl ester is very elaborate and allows me to elaborate.
The first method may be started from a phenyl compound containing a specific substituent. First take 3-cyano-4-hydroxybenzoic acid and the like, and replace its hydroxyl group with 2-methylpropyl halide, such as 2-methylpropyl bromide, in the presence of a base, by nucleophilic substitution to obtain 3-cyano-4 - (2-methylpropoxy) benzoic acid. Subsequently, this acid is reacted with a compound containing a thiazole structure. Ethyl 4-methyl-5-thiazole carboxylate is usually prepared by ethyl 2-bromoacetoacetate and thiourea, and then it is esterified with the above-mentioned 3-cyano-4- (2-methylpropoxy) benzoic acid under the action of condensation agent such as dicyclohexylcarbodiimide (DCC) and catalyst 4-dimethylaminopyridine (DMAP), and then the target product is obtained.
The second method can start with the construction of thiazole ring. In a suitable nitrile compound, such as 3-cyano-4- (2-methylpropoxy) phenylacetonitrile, with α-halogenated ketones, such as 2-bromo-4-methylpentyl-3-one, and a sulfur source such as potassium sulfide, in a suitable solvent such as ethanol, heated and refluxed to form a thiazole ring by cyclization. After esterification of thiazole derivatives, ethanol and concentrated sulfuric acid were used as esterification system, heating reaction, 2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4 -methyl-5-thiazole carboxylic acid ethyl ester.
Another method is to prepare the intermediate containing thiazole and benzene ring fragments first. With 2-methyl-4-amino-5-ethoxycarbonyl thiazole and 3-cyano-4- (2-methylpropoxy) benzaldehyde, under the action of acidic catalysts such as p-toluenesulfonic acid, through condensation reaction, Schiff base intermediate is generated, and then through reduction steps, such as reduction with sodium borohydride, the final product is obtained. This number method has its own advantages and disadvantages. It is necessary to follow the actual situation, considering the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.

2-% 5B3-cyano-4-% 282-methylpropoxy% 29 phenyl% 5D-4-methyl-5-thiazole carboxylic acid ethyl ester, this is a fine organic chemical. During storage and transportation, many points should be paid attention to.
First, the storage environment is the key. A dry, cool and well-ventilated place should be selected. If the environment is humid, the compound may react such as hydrolysis due to moisture invasion, resulting in damage to its quality. Temperature also needs to be strictly controlled. Excessive temperature may cause the compound to decompose, deteriorate, or even trigger safety accidents. And it should be kept away from fire and heat sources. Because it may be flammable, it may be dangerous to encounter open flames and hot topics.
Second, the packaging must be solid and tight. It is often packed in sealed containers to prevent air, moisture and compounds from coming into contact. Packaging materials also need to be carefully selected, and they must not chemically react with the compound, so as to avoid corrosion of the package and leakage of the compound.
Third, the transportation process should not be underestimated. When handling, be sure to handle it with care to avoid violent vibration and collision. Because of the chemical reaction under the action of vibration, collision, or due to the change of molecular structure, or the package may be damaged. The means of transportation should also be clean, dry, and equipped with fire protection, explosion protection and other safety facilities.
Fourth, when storing and transporting, relevant regulations and standards should also be strictly followed. Operators must be professionally trained to be familiar with the chemical compound's characteristics and safe operating procedures to ensure safe storage and transportation and avoid accidents.