2 3 Cyano 4 2 Methylpropoxy Phenyl 4 Methyl 1 3 Thiazole 5 Carboxylic Acid
quinoline thiophene imidazole thiazole

2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

    Specifications

    HS Code

    919633

    Chemical Formula C18H18N2O3S
    Molecular Weight 342.41
    Appearance Solid (predicted)
    Boiling Point Estimated around 504.4°C at 760 mmHg
    Solubility Poorly soluble in water, solubility in organic solvents like DMSO, methanol may vary
    Logp Estimated to be around 3.9 (lipophilicity measure)
    Pka Carboxylic acid pKa around 4 - 5 (estimated for the acidic group)
    Density Estimated density around 1.24 g/cm³
    Stability Stable under normal conditions, may decompose on heating or in presence of strong oxidizing agents

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    Frequently Asked Questions

    As a leading 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- [3-Cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid
    This is the naming of an organic compound. To clarify its chemical structure, it is necessary to analyze it according to the naming rules. "2 - [3-cyano-4 - (2-methylpropoxy) phenyl] - 4-methyl-1,3-thiazole-5-carboxylic acid", which can be separated and solved.
    "Thiazole" is a five-membered heterocycle containing sulfur and nitrogen, and 1,3-thiazolidine is the position of sulfur and nitrogen atoms in the ring. " 2 - [3-cyano-4- (2-methylpropoxy) phenyl] ", showing a thiazole ring with a phenyl group at the 2nd position, the phenyl group has a cyano group at the 3rd position (-CN), and a 2-methylpropoxy group at the 4th position (-O - CH - CH (CH) -)." 4-methyl ", with a methyl group (-CH) at the 4th position of the thiazole ring." 5-carboxylic acid "refers to the thiazole ring with a carboxyl group at the 5th position (-COOH).
    According to this analysis, draw its chemical structure: first draw a 1,3-thiazole ring, at the 2-position phenyl group, the phenyl group is distributed according to the said substituent; the 4-position methyl group is added, and the 5-position carboxyl group is connected. Its structure is: thiazole ring core, with a specific substituent distribution next to it, which is the unique structure of an organic compound. Each group is connected according to the rules to form this complex and ordered chemical structure.
    What are the physical properties of 2- [3-Cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1, 3-thiazole-5-carboxylic acid
    2-% 5B3-cyano-4-% 282-methylpropoxy% 29 phenyl% 5D-4-methyl-1% 2C3-thiazole-5-carboxylic acid, this is an organic compound. Looking at its physical properties, it is mostly solid at room temperature, but it also depends on the surrounding environmental conditions. The determination of its melting point, under specific experimental conditions, may be able to obtain exact values, which are crucial for identification and purity determination.
    When it comes to solubility, it may show some solubility in common organic solvents, such as dichloromethane and chloroform. Due to the molecular structure of the compound, it contains specific functional groups and interacts with organic solvent molecules. In water, its molecular polarity is not well matched with water, so its solubility may be relatively poor. < Br >
    Then again, when it is pure, it may be white to white powder, but if it contains impurities, the appearance may change, and the color may be slightly gray. In addition, the stability of the compound is also an important property. In the general environment, if there is no special condition to trigger, the chemical properties may be relatively stable. In case of extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may be damaged, triggering chemical reactions and causing chemical properties to change. The investigation of its physical properties will help to gain a deeper understanding of this compound and lay the foundation for subsequent research and application.
    What is the synthesis method of 2- [3-Cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid
    To prepare 2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-1,3-thiazole-5-carboxylic acid, the method is as follows:
    Take an appropriate amount of 3-cyano-4-hydroxybenzaldehyde and dissolve it in a suitable organic solvent, such as dichloromethane or N, N-dimethylformamide (DMF). This solvent should be pure and anhydrous so as not to affect the reaction process.
    Take another 2-methylpropyl halide, such as 2-methylpropyl bromide or 2-methylpropyl chloride, add an appropriate amount of alkali, such as potassium carbonate or sodium carbonate, and add it to the above solution containing 3-cyano-4-hydroxybenzaldehyde. The function of the base is to promote the nucleophilic substitution reaction. The reaction temperature should be controlled in a moderate range, or at room temperature, or slightly heated to 40-60 degrees Celsius, depending on the specific situation. When stirring for a few times, until the reaction is complete, the reaction progress can be monitored by thin layer chromatography (TLC). < Br >
    After the reaction is completed, the reaction solution is treated, extracted, or filtered to separate the product containing 3-cyano-4- (2-methylpropoxy) benzaldehyde.
    Then add this product to a suitable organic solvent with thioacetamide and an appropriate amount of acid catalyst, such as p-toluenesulfonic acid, and heat it back. The acid catalyst can accelerate the reaction and promote the formation of thiazole rings. During the reaction process, pay close attention to the reaction status and control the reaction time and temperature.
    After the reaction is completed, the crude product can be obtained by cooling, filtering, washing, drying and other processes. Then by means of column chromatography or recrystallization, the final product is pure 2- [3-cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid. The whole process needs to pay attention to the reaction conditions of each step to ensure fine operation to improve the purity and yield of the product.
    What is the main use of 2- [3-Cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid
    2 - [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-1,3-thiazole-5-carboxylic acid, this is an organic compound. Its structure is composed of thiazole ring, benzene ring and other specific substituents. It has a wide range of uses and is often used as a key intermediate in drug synthesis in the field of medicine. Due to its unique chemical structure, it can be chemically modified to obtain specific bioactive compounds for the development of drugs for the treatment of various diseases, such as anti-tumor, antibacterial and other drugs. In the field of pesticides, it also has important applications, and may become a new type of pesticide active ingredient. With its chemical properties, it can achieve the effects of weeding, insecticide and sterilization, and help agricultural pest control and improve crop yield and quality. In the field of materials science, it may be able to participate in the synthesis of special materials to give special properties to materials, such as improving material stability and optical properties.
    2- [3-Cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid in the market prospects
    There is now a compound named 2 - [3-cyano-4 - (2-methylpropoxy) phenyl] - 4-methyl-1,3-thiazole-5-carboxylic acid. This is an organic compound with a wide range of uses in scientific research and pharmaceutical and chemical fields.
    Looking at the market, its prospects are promising. From the perspective of scientific research, many chemical research institutions are very interested in compounds containing structures such as thiazole and cyanyl. These structures often contain unique chemical activities and properties, which are the key to the creation of new compounds and the exploration of reaction mechanisms. This compound may be a pioneer in scientific research, assisting the exploration of new reactions and new synthesis paths, and shining brightly in the field of basic research in organic chemistry.
    In the field of pharmaceutical chemistry, thiazole-containing compounds often have antibacterial, anti-inflammatory, anti-tumor and other biological activities. This 2 - [3-cyano-4- (2-methylpropoxy) phenyl] -4-methyl-1,3-thiazole-5-carboxylic acid has been rationally modified and modified, and may become a lead compound with great potential, providing a cornerstone for the research and development of new drugs. Today's pharmaceutical market is hungry for innovative drugs. This compound is expected to emerge in the field of anti-disease drugs through in-depth research and development, and meet unfinished clinical needs.
    Furthermore, with the improvement of chemical technology, the synthesis process of this compound may be continuously optimized, the cost is reduced, and the yield is improved, paving the way for its large-scale production and marketing activities. Therefore, in general, 2- [3-cyano-4- (2-methylpropoxy) phenyl] - 4-methyl-1,3-thiazole-5-carboxylic acid has a bright future in the market, and there are many opportunities. It is expected to create a new situation in the fields of scientific research and pharmaceutical and chemical industry, and benefit many parties.