2-(2-AMINOTHIAZOLE-4YL)-2-(TERT-BUTOXYCARBONYL)-ISOPROPOXYIMINO ACETIC ACID

2 - (2 - aminopyridine - 4 - yl) - 2 - (tert-butoxycarbonyl) isobutoxycarbonyl aminoformylacetic acid, which is widely used. It is often used as a key intermediate in the synthesis of medicine. Due to its special structure, it can construct complex and delicate drug molecular structures through various chemical reactions, helping to create new specific drugs.
The field of research and development of antibacterial drugs can participate in the construction of specific active groups, and the resulting drugs can effectively act on key bacterial targets, interfere with the normal physiological metabolism of bacteria, and achieve the purpose of antibacterial. The development of anti-tumor drugs also has its own role, by binding to specific targets of tumor cells, or affecting the signaling pathways of tumor cells, or interfering with their proliferation and differentiation process, thereby inhibiting the growth and diffusion of tumor cells.
In the field of organic synthetic chemistry, it is an important cornerstone for the construction of complex organic molecules. With its unique functional group characteristics, it can be skillfully spliced with other organic compounds through many classic organic reactions such as esterification, amidation, and condensation, to achieve precise construction of complex organic molecules, providing the possibility for the synthesis of organic materials with unique structures and properties, such as in the field of optoelectronic materials, or to develop new materials with special optical and electrical properties. Due to its relatively stable chemical properties and controllable reactivity, in various synthetic reactions, the target product can be efficiently prepared according to specific needs by rationally designing reaction conditions and steps. Therefore, in the field of organic synthetic chemistry, its importance is self-evident, and it is a key factor in promoting the progress of drug development and organic synthetic chemistry.

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This is an organic compound with specific physical properties. It may be solid under normal conditions, and its color may be white to slightly yellow. The melting point of this substance is quite high. Due to the strong interaction force between molecules, it needs a higher temperature to cause it to melt. The specific melting point may vary depending on the purity, about [X] ° C to [X] ° C.
This substance has unique solubility. In common organic solvents, such as ethanol and acetone, it has poor solubility. Due to its molecular structure characteristics, it has weak forces with organic solvent molecules. However, in some strong polar solvents, it may have certain solubility, which can form specific interactions with strong polar solvent molecules.
Its density is also an important physical property. The relative density is about [X], which is slightly higher than that of water. Due to the tight molecular structure, the mass per unit volume is larger.
In addition, the substance has extremely low volatility. Due to its strong intermolecular force, it requires high energy for molecules to escape from the liquid phase and enter the gas phase. Therefore, under normal temperature and pressure, the volatilization rate is extremely slow.
Its appearance may be a crystalline powder with fine and uniform particles. Due to the orderly arrangement of molecules, a regular crystal structure is formed during the crystallization process. These physical properties are of great significance for its application in chemical, pharmaceutical and other fields, and can help determine its applicable scenarios and processing methods.

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This substance is named 2- (2-hydroxypyridine-4-yl) -2- (butyl-1-oxo) isobutoxy acetaminoacetic acid, and its chemical properties are as follows:
Structurally, the molecule contains a number of different functional groups, hydroxypyridyl, butyl-1-oxy acetamide, and carboxylic groups, which endow it with diverse chemical activities.
Hydroxy (-OH) in hydroxypyridyl groups has a certain hydrophilicity and can participate in the formation of hydrogen bonds, thus affecting the solubility of the substance in solution and the interaction with other molecules. At the same time, the presence of the pyridine ring makes the molecule have certain aromaticity and alkalinity. The nitrogen atom on the pyridine ring can be used as an electron pair donor to complex or react with some metal ions or electrophilic reagents.
Butyl-1-oxo provides the carbonyl (C = O) functional group for the molecule, and the carbonyl group has a strong polarity, which makes the molecule have a certain reactivity. Carbonyl carbon atoms are partially positively charged and vulnerable to attack by nucleophiles, and reactions such as nucleophilic addition can occur.
The isobutoxy acetamide moiety, in which the ether bond (C-O-C) is relatively stable, but may break under some strong acidic or strong basic conditions. The amide bond (-CONH -) in the acetamide group has a certain stability, but it can undergo hydrolysis reaction under the catalysis of acid and base, and fracture to form corresponding acids and amines.
The final carboxyl group (-COOH) is the main reason for the acidic behavior of the molecule. It can ionize hydrogen ions in aqueous solution and has the general properties of acids, such as neutralization reaction with bases and reaction with active metals to generate hydrogen gas. At the same time, carboxyl groups can also participate in esterification reactions, and alcohol can form ester compounds under acid catalysis. In general, 2 - (2 - hydroxypyridine - 4 - yl) - 2 - (butyl - 1 - oxy) isobutoxy acetaminoacetic acid has rich chemical reactivity due to its complex structure and various functional groups, and may show unique application value in organic synthesis, medicinal chemistry and other fields.

To prepare 2 - (2 - hydroxypyridine - 4 - yl) - 2 - (tert-butoxycarbonyl) ethyl isobutoxycarbonyl carbamate, the method is as follows:
First take an appropriate amount of 2 - hydroxypyridine - 4 - boronic acid, mix it with a reagent containing halogenated isobutoxycarbonyl carbamate ethyl ester in a suitable solvent. This solvent can be selected from dioxane, tetrahydrofuran and the like, and an appropriate amount of bases, such as potassium carbonate, sodium carbonate, etc., are added to assist the reaction. At the same time, palladium catalysts, such as tetra (triphenylphosphine) palladium, are introduced and the reaction is stirred at an appropriate temperature. The purpose of this step is to integrate 2-hydroxypyridine-4-yl into the structure of ethyl isobutoxycarbonyl carbamate through a palladium-catalyzed coupling reaction to generate an intermediate containing 2- (2-hydroxypyridine-4-yl) isobutoxycarbonyl carbamate.
Then, the above intermediate product is reacted with a tert-butoxy carbonylation reagent, such as di-tert-butyl dicarbonate, in the presence of suitable organic bases, such as triethylamine, N, N-diisopropylethylamine, etc., in organic solvents such as dichloromethane and chloroform. Control the reaction temperature and time, so that tert-butoxycarbonyl can successfully replace the hydrogen at a specific position, so as to complete the synthesis of 2- (2-hydroxypyridine-4-yl) - 2- (tert-butoxycarbonyl) isobutoxycarbonyl carbamate ethyl ester. After the reaction, the target product can be obtained by conventional separation and purification methods such as extraction, washing, drying, column chromatography, etc. The whole synthesis process needs to pay attention to the precise control of the reaction conditions. The proportion of reactants in each step, temperature, time and other factors have an important impact on the yield and purity of the product.

I think what you are asking is about "the price range of 2- (2-hydroxypyridine-4-yl) -2- (tert-butoxycarbonyl) isobutoxycarbonyl carbamic acid in the market". However, the price of this product often changes for a variety of reasons, which is difficult to determine.
First, the supply and demand of the market is the primary influence on the price. If there are many buyers of this product, and there are few suppliers, the price will rise; if the supply exceeds the demand, the price will drop. Second, the cost of its production is also the key. The price of raw materials, the process of production, the cost of energy consumption, etc., are all related to cost. If the cost is high, the price will be high, and if the cost is low, the price will drop. Third, the quality is also linked to the price. The price of the superior is high, and the price of the second is low. It is common sense in the world. Fourth, the competition in the market also has an impact. Businesses compete, or reduce prices to seize the market, in order to attract customers.
As far as I know, in today's market, the price of such fine chemicals often varies greatly depending on different merchants, different specifications, and different purity. For ordinary purity and conventional specifications, the price may be a few yuan to tens of yuan per gram; for high purity and special specifications, the price may reach more than 100 yuan per gram, or even higher. However, this is only a rough estimate. The actual price should be consulted with chemical raw material suppliers, chemical reagent sellers, etc., subject to the real-time market conditions in the city.