2-(2-Aminothiazole-4-Yl)-Z-Hydroxyimino Acetic Acid

2-%282-%E6%B0%A8%E5%9F%BA%E5%99%BB%E5%94%91-4-%E5%9F%BA%29-Z-%E7%BE%9F%E5%9F%BA%E4%BA%9A%E6%B0%A8%E5%9F%BA%E4%B9%99%E9%85%B8%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E4%B8%89%E5%A4%A7%E7%A7%8D%E5%A6%82%E4%B8%8B:
First, the field of medicine. This compound has a unique impact on human physiology and is often used as a key active ingredient in the process of drug development. It can act on specific cell receptors, regulate biochemical reactions in the body, or act on certain disease-related targets, and help create new therapeutic drugs. For example, in the development of drugs for chronic diseases, with its special structure and activity, it is possible to develop drugs with more curative effect and less side effects, bringing good news to patients.
Second, the field of materials science. Because of its special chemical properties, it can participate in the synthesis and modification of materials. When preparing high-performance polymer materials, introducing them as additives or structural units can significantly improve the physical properties of the material, such as improving the stability, flexibility or enhancing its mechanical strength. For example, in the production of some high-end plastic products or advanced composite materials, it can optimize the material properties to meet the needs of different fields for special materials.
Third, agricultural use. In agricultural production, it can be used to develop new pesticides or plant growth regulators. As a pesticide, it can precisely act on specific physiological processes of pests, play an efficient control effect on pests, and is relatively friendly to the environment, reducing the impact of chemical pesticide residues on the ecology. As a plant growth regulator, it can regulate the growth and development process of plants, improve the yield and quality of crops, and promote sustainable agricultural development.

To prepare 2- (2-aminopyridine-4-yl) -Z-fluorinated aminoacetoxy acid, there are many synthesis methods, and each has its advantages and disadvantages. The choice depends on the specific situation.
First, use 2-aminopyridine-4-formaldehyde as the starting material. First, let it perform nucleophilic addition reaction with fluorine-containing nucleophiles. This step requires careful selection of reaction conditions, such as temperature and solvent, to ensure that the addition product is pure. Then the addition product is modified, oxidized or other suitable reactions, to obtain a carboxyl-containing intermediate. Then through the esterification reaction, the acetoxy group is added. During this period, the ratio of catalyst and reactant needs to be fine-tuned to obtain the target product. The starting materials in this way are relatively easy to obtain, but the steps are complicated, and the yield of each step is related to the final effect.
Second, start from 2-halogenated pyridine-4-derivatives. With a fluorinated amination reagent, the halogen atom is replaced by a fluorinated amino group. This reaction requires the assistance of a suitable base agent and a catalyst to improve the reaction activity and selectivity. Then an amino group is introduced at the 2-position of the pyridine ring, which can be achieved by nucleophilic substitution or other classic organic reactions. Finally, carboxyl and acetoxy groups are introduced through a series of reactions to modify the side chain functional groups. This route requires proper planning of the reaction sequence to avoid unnecessary side reactions.
Third, the construction strategy of pyridine ring is used. With suitable raw materials, pyridine ring is constructed by cyclization reaction, and necessary functional groups such as amino and fluoro amino groups are introduced simultaneously during cyclization. This process requires extremely high control of reaction design and conditions. If successful, it may simplify the steps and improve the overall efficiency.
Synthesis is not achieved overnight. All methods need to be tested and optimized repeatedly, taking into account the cost of raw materials, reaction conditions, yield purity and many other factors, in order to find the best method and achieve the synthesis of 2- (2-aminopyridine-4-yl) -Z-fluorinated aminoacetoxy acid.

2- (2-aminopyridine-4-yl) -Z-prolylaminoacetic acid is an organic compound, which is of great significance in the field of organic synthesis and medicinal chemistry. Its physical and chemical properties are as follows:
1. ** Properties **: This compound is usually white to light yellow solid, and its appearance is powder or crystalline. This property is related to its intermolecular forces and arrangement. Intermolecular hydrogen bonds, van der Waals forces, etc. interact to form a tight and ordered structure and assume a solid state.
2. ** Solubility **: In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), the compound has certain solubility. Dichloromethane has moderate polarity and can form interactions with some groups of the compound; DMF has strong polarity and can dissolve the compound through hydrogen bonding and other effects. However, its solubility in water is poor. Because of the large proportion of hydrophobic parts in the molecular structure, water molecules interact weakly with hydrophobic groups, making it difficult to disperse and dissolve them.
3. ** Melting point **: The melting point is in a specific temperature range, which is determined by the intermolecular force. The stronger the intermolecular force, the higher the energy required to destroy the lattice structure and the higher the melting point. There are various interactions within the molecules of the compound, which together determine its melting point.
4. ** Stability **: Under normal conditions, the compound is relatively stable. However, in case of extreme conditions such as strong acids, strong bases or high temperatures, its structure may change. Because of some chemical bonds in the molecule, such as amide bonds, carbon-nitrogen bonds, etc., hydrolysis, cracking and other reactions may occur under acid-base catalysis; high temperature will intensify the thermal movement of the molecule, causing chemical bond breakage and affecting stability.
5. ** Acid-basic **: The amino group in the molecule has a certain alkaline nature and can accept protons; the carboxyl group is acidic and can give protons. This makes the compound exist in different ion forms under different pH environments, affecting its solubility, reactivity and other properties. In acidic solutions, the amino group is protonated; in alkaline solutions, the carboxyl group is deprotonated.

I have not heard of the exact price range of "2 - (2 - aminopyridine - 4 - yl) - Z - cyanaminoacetic acid" on the market. However, if you want to know its price, you can find it from various ways.
First, the market is a medicinal material store, a chemical raw material store, or there is such a thing. Ask the shopkeeper or guy there, or you can get the actual price. This is a way to inquire in person on the spot, you can face the merchant directly and get first-hand information.
Second, in this world, the Internet is convenient. It can be searched on various chemical product trading platforms and e-commerce. Many merchants display goods on such platforms, marked with prices. < Br >
Third, consult pharmaceutical workshops and chemical research institutions. They often need this product and must know the price market. Or you can get the common price range in the industry from there.
However, the price of this product may vary due to the quality, the distance of the place of origin, and the amount of supply and demand in the city. Those with good quality, the price may be high; the place of origin is remote and the transportation is difficult, and the price will also rise; if there are many people in the market who want it, and there are few people who supply it, the price will be higher; on the contrary, if the supply exceeds the demand, the price may drop. Therefore, if you want to know its exact price, you need to visit it several times and consider various factors comprehensively.

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2- (2-hydroxypyridine-4-yl) -Z-prolyl-hydroxyacetic acid is an important organic compound, its synthesis is quite difficult, and it is widely used in medicine, chemical industry and other fields. Many scientific research institutions and enterprises have invested in studying its preparation process. The following are related manufacturers:
First, Suzhou 100% Biochemical Technology Co., Ltd. The company has been focusing on the field of biochemical industry for many years and has accumulated rich experience in the production of 2- (2-hydroxypyridine-4-yl) -Z-prolyl-hydroxyacetic acid. Its production process is advanced, the product quality is high, and with a good reputation and stable product supply, it has a firm foothold in the market and is deeply trusted by customers.
Second, Shanghai University School of Pharmacy Chemistry Starting Company. Relying on the strong scientific research strength of Shanghai University, the company's scientific research team has profound achievements in the field of organic synthesis. Carried out in-depth research on 2 - (2-hydroxypyridine-4-yl) -Z - prolyl hydroxyacetic acid, and successfully developed efficient synthesis methods. The products produced are of high purity and excellent performance, and are widely used in cutting-edge fields such as pharmaceutical research and development.
Third, Peking University School of Pharmacy Chemistry Starting Company. As a spin-off enterprise of top domestic university scientific research institutions, Peking University Pharmacy School Chemistry Starting Company adheres to the spirit of rigorous academic research and innovation. In the production and preparation of 2- (2-hydroxypyridine-4-yl) -Z-prolyl hydroxy acetic acid, top scientific research talents are brought together, and with the help of advanced experimental equipment and technology, the production process is continuously optimized, and the product quality reaches the international leading level, providing solid support for the development of related fields.