What is the main use of 2- (2-aminothiazole-4-yl) - (Z) -2- (methoxycarbonyl methoxyimino) acetic acid?
2 - (2 - hydroxybutyraldehyde - 4 - yl) - (Z) - 2 - (methoxymethoxyacetoxy) acetic acid, which is often used as an intermediary in organic synthesis. In the field of organic synthesis, many complex and delicate compounds need to be gradually constructed, and the special structure of this compound can be skillfully combined with other molecules through specific chemical reactions.
Its hydroxyl, aldehyde, methoxy and other functional groups are all active check points for reactions. For example, hydroxyl groups can participate in esterification reactions, react with carboxylic acids to form corresponding ester compounds. This reaction is often used in the synthesis of fragrances and drugs to add specific properties of molecules. The presence of aldehyde groups can cause oxidation, reduction, condensation and many other reactions to occur. For example, in some condensation reactions, aldehyde groups can react with compounds containing active hydrogen to form new carbon-carbon bonds or carbon-heteroatomic bonds, thereby expanding the carbon skeleton of molecules and laying the foundation for the synthesis of more complex structures.
Furthermore, the more complex functional group of methoxy methoxy acetoxy group also plays a unique role in the reaction. It can be selectively removed or converted under specific conditions, providing precise control for the synthesis process, guiding the reaction in the desired direction, and then synthesizing target products that meet specific needs. It is of great significance in the synthesis of fine chemicals and drug lead compounds.
What are the synthesis methods of 2- (2-aminothiazole-4-yl) - (Z) -2- (methoxycarbonyl methoxyimino) acetic acid
To prepare 2 - (2 - aminopyridine - 4 - yl) - (Z) - 2 - (methoxy methoxy acetamido) acetic acid, the following methods can be used:
First, start with 2 - (2 - aminopyridine - 4 - yl) ethanol, oxidize to obtain the corresponding aldehyde, then condensate with methoxy methoxy acetyl chloride, and then oxidize and hydrolyze to obtain the target product. In this oxidation step, a mild oxidant such as Dyce-Martin oxidant can be selected to maintain the stability of the pyridine ring and amino group. When condensation, it is necessary to choose a suitable alkali agent, such as triethylamine, to create an alkaline environment and promote the reaction.
Second, with 2- (2-nitropyridine-4-yl) acetic acid as the initial material, the nitro group is first reduced to an amino group, and then reacted with methoxymethoxyacetyl halide. Nitro reduction is often used as a catalytic hydrogenation method, with palladium carbon as the catalyst and hydrogen as the reducing agent. This process is gentle and efficient. In subsequent halide reactions, pay attention to the reaction conditions to prevent side reactions. < Br >
Third, with 2- (2-aminopyridine-4-yl) acetaldehyde as the base, it can be obtained by condensation reaction with methoxy methoxy acetate under alkaline conditions, and then oxidized. The alkaline environment can be created by alkaline agents such as sodium alcohol, and the condensation reaction requires temperature control and reaction time to ensure the smooth reaction. The oxidation step can be selected according to the actual appropriate oxidant.
Each method has its advantages and disadvantages. According to the availability of raw materials, cost and difficulty of reaction conditions, the best path should be selected to efficiently prepare 2- (2-aminopyridine-4-yl) - (Z) -2 - (methoxymethoxyacetamido) acetic acid.
What are the physicochemical properties of 2- (2-aminothiazole-4-yl) - (Z) -2- (methoxycarbonyl methoxyimino) acetic acid
2 - (2 - aminopyridine - 4 - yl) - (Z) - 2 - (methoxy methoxy) acetic acid, its physical and chemical properties are as follows:
This compound has a specific chemical structure and is composed of different groups. In appearance, it is often white to white solid powder, which is derived from its intermolecular interaction force and arrangement. In terms of solubility, it has a certain solubility in organic solvents such as dichloromethane, N, N-dimethylformamide, but the solubility in water is relatively low. Due to the balance of hydrophilic and hydrophobic groups in the molecule, hydrophobic groups dominate, making it difficult to dissolve in water with high polarity.
Its melting point is within a certain range, and the specific value is determined by accurate experiments. It is a reflection of the energy required by the molecule to overcome the lattice energy, reflecting the strength of intermolecular forces. In terms of stability, under conventional conditions, the chemical properties are relatively stable. In case of extreme conditions such as strong acids, strong bases or high temperatures, some chemical bonds in the structure may break or rearrange. This is because strong acids and bases can react with specific groups, and high temperatures provide enough energy to activate chemical bonds.
The physicochemical properties of this compound have an important impact on its synthesis, storage and application. Understanding these properties can help to rationally design synthetic routes, select suitable storage conditions, and explore its potential uses in organic synthesis, pharmaceutical chemistry, and other fields.
What is the price range of 2- (2-aminothiazole-4-yl) - (Z) -2- (methoxycarbonyl methoxyimino) acetic acid in the market?
Alas! It is not easy to know the market value of 2- (2-ethylamine-4-yl) - (Z) -2- (methoxylmethoxy-methoxy) acetic acid. Such a chemical substance, its price is high, it is as floating as the sky, and it is affected by such factors.
First, the supply of raw materials, if the raw materials are not available in the ground, and the government decrees that the supply is low, the supply will rise. On the contrary, if the raw materials are not abundant, it will not be easy to make.
Second, it is easy to make. If the synthesis method is complex, it requires high-precision technology and high-efficiency, and it consumes a lot of energy, and it will be high. If there is an easy way, the cost will be reduced and the cost will also be reduced.
Third, the demand of the market. If the demand for this product in the industrial, chemical and other fields increases greatly, and the demand for it is due to supply, it must be reduced. If the demand is sluggish, the supply is due to demand, and the supply will fall.
However, I have been able to find this 2 - (2 - ethyl ethylamine - 4 - yl) - (Z) - 2 - (methoxymethoxy methoxy group) acetic acid. Or because this material is not remote, the market does not circulate. If you want to know about it, you can't go to the chemical raw material market and sell it to merchants; or to the chemical industry, or to the exchange of people with each other.
What are the application fields of 2- (2-aminothiazole-4-yl) - (Z) -2- (methoxycarbonyl methoxyimino) acetic acid
2 - (2-hydroxyurea-4-yl) - (Z) - 2 - (methoxymethoxymethoxy) acetic acid, this compound has applications in medicine, chemical industry and many other fields.
In the field of medicine, it may occupy a place in the development of anti-tumor drugs. Hydroxyurea itself is a commonly used anti-tumor drug, which can inhibit nucleotide reductase, hinder DNA synthesis, and then inhibit tumor cell proliferation. This compound may use its unique structure to optimize pharmacological properties, improve the targeting and efficacy of specific tumor cells, and may also reduce toxic and side effects, providing a new strategy for cancer treatment.
In the chemical industry, it can be used as an intermediate in organic synthesis. With its complex and reactive structure, it can participate in a variety of organic reactions for the construction of more complex organic compounds. For example, by condensation and substitution reactions with other compounds containing specific functional groups, materials with special properties, such as functional polymer materials, liquid crystal materials, etc., are prepared to provide a raw material basis for chemical product innovation.
In the field of pesticides, it may have the potential to develop new pesticides. Its structural characteristics may endow the ability to inhibit or kill certain pests and bacteria, and compared with traditional pesticides, it may have advantages such as environmental friendliness and low residue, which is conducive to the development of green and environmentally friendly pesticides to meet the needs of sustainable agricultural development.
It can be seen from the above that 2- (2-hydroxyurea-4-yl) - (Z) -2- (methoxymethoxymethoxy) acetic acid has shown application prospects in many important fields, which is of great significance for promoting the development of pharmaceutical, chemical, pesticide and other industries.