1 3 Thiazole 5 Carboxylic Acid
quinoline thiophene imidazole thiazole

1,3-thiazole-5-carboxylic acid

Taiy Chemical

Specifications

HS Code

578632

Name 1,3-thiazole-5-carboxylic acid
Molecular Formula C4H3NO2S
Molecular Weight 129.14 g/mol
Appearance Solid (usually white to off - white)
Melting Point 199 - 203 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Acidity Pka Approximately 3.9
Stability Stable under normal conditions, but may react with strong oxidizing agents
Odor Odorless or faint odor
Hazard Irritant to eyes, skin and respiratory system
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General Information
Frequently Asked Questions
What is the main use of 1,3-thiazole-5-carboxylic acid?
The main use of 1,3-butadiene-5-carboxyl group, commonly found in the field of chemical synthesis.
1,3-butadiene, as an important organic chemical raw material, has a conjugated double bond structure and active properties. It can participate in a variety of polymerization reactions, such as the preparation of cis-butadiene rubber. This rubber has good wear resistance, elasticity and cold resistance. It is widely used in tire manufacturing, which can improve the grip and service life of tires and ensure vehicle safety. In the field of synthetic styrene-butadiene rubber, styrene-butadiene rubber has excellent comprehensive properties and is widely used in rubber products such as automobile tires, hoses, tapes, etc., to meet different industrial needs.
The 5-carboxyl group can impart specific chemical properties and reactivity to the compound. Compounds containing carboxyl groups can undergo esterification reactions, and esters are formed with alcohols under the action of catalysts. Esters are widely used in the fields of fragrances, coatings, plastic plasticizers, etc. For example, they can add unique aromas in fragrances and improve film-forming properties in coatings. Carboxyl groups can also carry out acid-base neutralization reactions, which can be used to adjust the pH of reaction systems, or to prepare compounds with specific pH. In drug synthesis, it helps to adjust the solubility, stability and biological activity of drug molecules, and improve drug efficacy.
1,3-butadiene-5-carboxyl groups can play a key role in many industrial and scientific research fields through rational design and chemical reactions, providing strong support for the development of materials science, drug research and development and other industries.
What are the physical properties of 1,3-thiazole-5-carboxylic acids
The physical properties of 1% 2C3-ether aldehyde-5-carboxylic acid, in general, ether aldehyde, volatile, often liquid, at room temperature, has a special odor, miscible in organic solvents, such as ethanol, ether, etc., but limited solubility in water. Its chemical properties are active, and aldehyde groups can cause it to participate in oxidation, reduction and addition reactions.
As for 5-carboxylic acids, they are mostly solid or liquid, depending on their structure. Acidic, can neutralize with bases to form corresponding salts and water. Its carboxyl groups can participate in esterification reactions and combine with alcohols to form esters and water. In terms of solubility, lower-grade carboxylic acids are soluble in water. However, as the carbon chain increases, the solubility in water gradually decreases, but they are more soluble in organic solvents.
Both are widely used in industrial and scientific research fields. Ether aldehyde is often used in organic synthesis and is a key intermediate for the preparation of complex organic compounds. 5-carboxylic acids are indispensable in many aspects of pharmaceuticals, fragrances and polymer materials synthesis, and play an important role in regulating the chemical reaction process and product properties. They have unique physical properties and have significant applications in different branches of chemistry. They are the cornerstone of the development of organic chemistry.
Is the chemical properties of 1,3-thiazole-5-carboxylic acid stable?
1% 2C3-pyrimidine-5-carboxylic acid is one of the organic compounds. Whether its chemical properties are stable needs to be investigated in detail.
In terms of self-structure, the pyrimidine ring has a certain stability. This ring is composed of two nitrogen atoms and four carbon atoms, and is composed of a six-membered heterocyclic ring structure. The existence of the conjugated system gives it a certain aromaticity. The aromaticity characteristic gives the molecule additional stability because the electron cloud is uniformly distributed throughout the ring system, reducing the energy of the molecule. In this compound, the stability of the pyrimidine ring lays the foundation for the overall stability.
However, the carboxyl group attached to the 5-position also affects its stability. The carboxyl group is acidic, and under certain conditions, reactions such as acid-base neutralization can occur. In an alkaline environment, the carboxyl group easily loses protons and forms carboxylic salts. This process may affect the overall structure and stability of the molecule.
In addition, the chemical reactivity depends not only on its own structure, but also on environmental factors. When the temperature increases, the thermal motion of the molecule intensifies, the reactivity enhances, or the stability decreases; under light conditions, some compounds will undergo photochemical reactions. If 1% 2C3-pyrimidine-5-carboxylic acid is sensitive to light, its stability is also affected.
Overall, the stability of 1% 2C3-pyrimidine-5-carboxylic acid cannot be generalized, but depends on specific conditions. Under normal temperature, neutral and no special light conditions, based on the aromaticity of the pyrimidine ring, it may have a certain stability; but under specific conditions such as acid-base environment changes, temperature and light changes, its chemical properties may change, and the stability will also change.
What are the synthesis methods of 1,3-thiazole-5-carboxylic acid?
There are many ways to synthesize 1% 2C3-sandalwood-5-oleic acid, which are listed as follows:
First, it can be obtained by hydrolysis of natural oils and fats. The oil is an ester compound formed by glycerol and fatty acids. Under appropriate catalysts and conditions, the oil is hydrolyzed, and this process is like cooking in a kettle, which is meticulous and orderly. The oil encounters water and is decomposed into glycerol and fatty acids with the help of a catalyst. Then it is separated and purified by a process similar to sifting sand for gold to obtain oleic acid. This is a traditional method. It is popular because of its natural raw materials and a wide range of sources, such as common vegetable oils, soybean oil, and peanut oil.
Second, chemical synthesis is also a feasible way. Petrochemical products are used as starting materials, such as ethylene, propylene, etc. After a series of complex chemical reactions, a carbon chain structure is constructed, which is like building an exquisite pavilion. Every brick and tile needs to be precise. Then through the conversion of functional groups, carboxyl groups and other required groups are gradually introduced to synthesize oleic acid. Although this approach has a stable source of raw materials, the synthesis steps are complicated, and the reaction conditions are strict. It requires precise control of temperature, pressure and other parameters, and it is easy to produce side reactions. It is like walking in a narrow diameter, and it will deviate from the direction if you are not careful.
Third, microbial fermentation methods have also emerged. Select specific microbial strains, such as certain yeasts and molds. Placing suitable carbon sources, nitrogen sources and other nutrients in a suitable fermentation environment is like creating a comfortable home for microorganisms. Microorganisms grow and multiply in this environment, and during their metabolism, oleic acid can be produced. This method is green and environmentally friendly, and the conditions are mild. However, the fermentation cycle is long, and the yield improvement is also challenged. It is like cultivating delicate flowers, which require patient care.
The above methods have advantages and disadvantages. In practical application, careful choices should be made according to factors such as specific needs, availability of raw materials, and cost considerations, in order to achieve twice the result with half the effort.
What is the price range of 1,3-thiazole-5-carboxylic acid in the market?
1% 2C3 - musk-5 - gallic acid is above the market, and its price range is related to various reasons. Musk is a precious fragrance and good medicine, and its price is high. In ancient times, musk was often used by court nobles and was fresh from the folk. Today, musk is either produced by artificially farmed musk musks or extracted according to other methods. Its price varies according to quality, source, supply and demand. Good quality musk can reach thousands of yuan per gram; second, it also costs hundreds of yuan.
As for 5 - gallic acid, it is often found in various plants and has a wide range of uses. It is used in medicine, chemical industry and other industries. Compared with musk, its price is much closer to the people. The ordinary quality 5 - gallic acid, the price per kilogram may be between a few hundred and a few thousand yuan. If the quality is higher, for special purposes, the price will also rise. However, in general, due to the relationship between production and demand, its price fluctuations are not as great as musk drama. Prices in the city often change with time, and the prices of these two also rise and fall with the market conditions. Businesspeople need to check the market often in order to make profits.