1 2 Thiazole 4 Carboxylic Acid
quinoline thiophene imidazole thiazole

1,2-thiazole-4-carboxylic acid

Taiy Chemical

Specifications

HS Code

577955

Chemical Formula C4H3NO2S
Molecular Weight 129.14 g/mol
Appearance Solid (usually white or off - white)
Melting Point 220 - 225 °C (approximate, can vary)
Boiling Point Decomposes before boiling
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Pka Value Typically around 3 - 4 (approximate for carboxylic acid group)
Odor Odorless or very faint odor
Crystal Structure Can form various crystal structures depending on crystallization conditions
Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents
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General Information
Frequently Asked Questions
What are the chemical properties of 1,2-thiazole-4-carboxylic acid?
1% 2C2-pentanediol-4-heptanoenoic acid is an organic compound. Its properties are both diol and enoic acid.
In terms of its physical properties, it may be liquid under normal conditions and has a certain viscosity. Because it contains hydroxyl groups (-OH) and carboxyl groups (-COOH), it has a certain polarity and has a certain solubility in water and some polar solvents. Hydroxyl groups can cause hydrogen bonds to form between molecules, which increases their boiling point. Compared with simple hydrocarbons, they have lower volatility.
In terms of chemical properties, hydroxyl alcohols have a typical reaction. It can be esterified with acids, such as co-heating with acetic acid, and using sulfuric acid as a catalyst to generate corresponding esters and water. In case of strong oxidants, such as potassium permanganate, the hydroxyl group can be oxidized to form an aldehyde group and then a carboxyl group.
The carboxyl group is also active. It can be neutralized with bases, such as reacting with sodium hydroxide to generate corresponding salts and water. It can also be esterified with alcohols to form esters. This reaction is reversible and often requires a catalyst and heating to promote its formation.
In addition, the carbon-carbon double bond in the molecule gives it the reactivity of olefins. It can be added to halogens (such as bromine) to break the double bond, and bromine atoms are added to the carbon atoms at both ends of the double bond to make the reddish-brown of the solution fade away. It can also be added with hydrogen under the action of a catalyst to form a saturated acid. In conclusion, 1% 2C2-pentanediol-4-heptanoenoic acid exhibits diverse chemical properties due to its functional groups, and has potential applications in organic synthesis and chemical engineering.
What are the common synthesis methods of 1,2-thiazole-4-carboxylic acid?
1% 2C2-pentanediol-4-heptanoenoic acid is an organic compound, and its common synthesis methods are as follows:
** 1. Stepwise construction of carbon chains and functional groups from common organic raw materials **
1. ** Selection and preliminary reaction of starting materials **:
Halogenated hydrocarbons or alcohols containing suitable carbon numbers can be selected as starting materials. If halogenated hydrocarbons are taken as an example, such as 1-bromobutane reacts with magnesium in anhydrous ethyl ether to generate Grignard reagent butyl magnesium bromide ($C_ {4} H_ {9} MgBr $). This reaction is carried out in an anhydrous and anaerobic environment. The Grignard reagent is extremely active and will react rapidly with water and oxygen and fail.
$C_ {4} H_ {9} Br + Mg\ xrightarrow [] {anhydrous ether} C_ {4} H_ {9} MgBr $
2. ** Carbon chain growth and functional group introduction **:
The prepared Grignard reagent is reacted with 3-pentenal to achieve carbon chain growth and introduce hydroxyl functional groups. After the reaction is completed, 2-pentene-1-heptanol can be obtained by hydrolysis with dilute acid. < Br > $C_ {4} H_ {9} MgBr + C_ {5} H_ {8} O\ xrightarrow [] {} C_ {12} H_ {22} O\ xrightarrow [] {H ^ +, H_ {2} O} C_ {12} H_ {24} O $
3. ** Hydroxygenation and Carboxyl Generation **:
Use a suitable oxidant, such as Jones Reagent ($CrO_ {3}/H_ {2} SO_ {4} $), to oxidize the hydroxyl group of 2-pentene-1-heptanol to carboxylic group to obtain 1% 2C2-pentanediol-4-heptanoenoic acid. Pay attention to control the reaction conditions during the reaction to avoid excessive oxidation.
$C_ {12} H_ {24} O + [O]\ xrightarrow [] {Jones reagent} C_ {12} H_ {22} O_ {3} $
** Second, by means of esterification reaction and subsequent conversion **
1. ** Esterification reaction **:
Esterification reaction occurs with 2-pentenol and n-heptanoic acid as raw materials under the catalysis of concentrated sulfuric acid to generate 2-pentenyl heptanoate. This reaction is a reversible reaction, which can be promoted by increasing the amount of a reactant or removing the product water in time.
$C_ {5} H_ {8} O + C_ {7} H_ {14} O_ {2}\ underset {\ Delta} {\ overset {H_ {2} SO_ {4}} {\ rightleftharpoons}} C_ {12} H_ {22} O_ {2} + H_ {2} O $
2. ** Hydrolysis of esters and functional group adjustment **:
Hydrolysis of 2-pentenyl heptanoate under basic conditions to generate the corresponding carboxylate, and then acidification treatment can obtain 1% 2C2-pentanediol-4-heptanoenoic acid. < Br > $C_ {12} H_ {22} O_ {2} + NaOH\ xrightarrow [] {H_ {2} O} C_ {12} H_ {21} O_ {2} Na + C_ {5} H_ {9} OH $
$C_ {12} H_ {21} O_ {2} Na + HCl\ xrightarrow [] {} C_ {12} H_ {22} O_ {3} + NaCl $
In which fields are 1,2-thiazole-4-carboxylic acids used?
1% 2C2-pentene-4-alkynic acid, which is used in many fields such as chemical industry, medicine, and materials.
In the field of chemical synthesis, it can be used as a key intermediate. Due to its structure containing carbon-carbon double bonds and carbon-carbon triple bonds, it has active chemical properties and can prepare complex organic compounds through various chemical reactions, such as addition and polymerization. For example, by addition to hydrogen halide, halogenated olefins can be formed; after polymerization, polymer materials with special properties can be prepared, which are widely used in plastics, rubber and other industries.
In the field of medicine, this substance may play an important role in drug development due to its unique chemical structure and activity. Or can be used as a lead compound, through structural modification and optimization, to develop new drugs with specific pharmacological activities. Studies have shown that compounds containing similar carbon-carbon unsaturated bond structures have certain effects on certain disease-related targets. 1% 2C2-pentene-4-alkynic acid or has potential value in the research and development of antibacterial, anti-inflammatory, anti-tumor and other drugs.
Materials science field, which can be used to prepare functional materials. Copolymerization with other monomers can endow materials with special properties. Such as the introduction of optically active groups to prepare photoresponsive materials; participate in the preparation of conductive polymers to improve the electrical properties of materials, and may have application prospects in optoelectronic devices, sensors, etc.
In conclusion, 1% 2C2-pentene-4-alkynic acid has shown broad application potential in the fields of chemical industry, medicine, and materials due to its unique structure. With the deepening of research, it is expected to generate more innovative applications.
What is the market price of 1,2-thiazole-4-carboxylic acid?
In today's world, the price of 1,2-pentanediol-4-hexenoic acid in the market is related to various factors and is complex.
First, the price of raw materials is the key. The production of this compound requires specific raw materials. If the production of raw materials changes due to weather, conditions, and decrees, the price will also fluctuate. If the raw materials are thin, the price will be high, and if the raw materials are abundant, the price will be flat. If the raw material production area is affected by disasters and the output decreases sharply, the cost of this compound will increase, and the price in the market will also rise.
Second, the complexity and simplicity of the manufacturing process also depend on the price. If the preparation method requires delicate utensils, cumbersome processes, and strict requirements on the environment and manpower, the cost will be large and the price will be high. If the new manufacturing process can save materials and labor, improve the yield, or the price can be reduced. However, the promotion of the new manufacturing process needs to consider its stability and safety, which also affects the cost and price.
Third, the supply and demand of the city will determine the price. If the demand for this product in the fields of medicine and chemical industry surges, and the production and supply are temporarily difficult to respond, the price will rise. On the contrary, if the supply exceeds the demand, the manufacturer will sell the goods, or reduce the price to meet the market. If an industry uses this product as a raw material, the demand will suddenly rise, but the production has not been expanded, and the price will rise rapidly.
Fourth, government regulations, taxes, etc., also have an impact. If environmental protection regulations are strict, manufacturers need to increase investment in production and disposal for compliance, and costs rise and prices rise. Changes in taxation will also make manufacturers different burdens and cause price fluctuations.
In summary, the market price of 1,2-pentanediol-4-hexenoic acid is not constant, and it changes with various factors such as raw materials, craftsmanship, supply and demand, and government orders. If the city wants to know the exact price, it should pay attention when it is carefully observed.
What are the safety and toxicity of 1,2-thiazole-4-carboxylic acids?
1% 2C2-pentene-4-alkynic acid is an organic compound, and its safety and toxicity need to be investigated in detail.
In terms of safety, this compound is in a stable state under normal temperature and pressure, if stored under appropriate conditions. However, as an organic chemical, it is at risk of combustion and explosion when exposed to open flames, hot topics or strong oxidants. Therefore, when storing and using, it must be kept away from fire sources, heat sources and strong oxidants, and in a well-ventilated place. During operation, appropriate protective equipment should be worn, such as protective gloves, goggles and gas masks, to prevent it from contacting the skin and respiratory tract.
When it comes to toxicity, the current research on the toxicity of 1% 2C2-pentene-4-alkynic acid may be relatively limited. However, similar compounds containing alkynyl and carboxyl groups may be irritating to a certain extent. If it comes into contact with the skin, it may cause redness, swelling and pain; if it comes into contact with the eyes, it may cause serious irritation to the eyes, or even damage vision. Once inhaled, or irritate the respiratory tract, cause symptoms such as cough and asthma. If taken inadvertently, it may cause corrosion and irritation to the digestive tract, causing nausea, vomiting, abdominal pain and other discomfort.
In summary, when handling 1% 2C2-pentene-4-alkynic acid, it is necessary to strictly follow the safety operating procedures and take protective measures. In the event of accidental contact, appropriate first aid measures should be taken immediately and prompt medical attention should be sought.