(S)-(-)-N-Tert-Butyl-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxamide

(S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide, which has a wide range of uses. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs. Or due to its unique chemical structure and activity, it can specifically bind with biological macromolecules in the body to regulate physiological processes, such as participating in the research and development of drugs in the nervous system, affecting the metabolism and transmission of certain neurotransmitters, or acting on the cardiovascular system, regulating physiological indicators such as blood pressure and heart rate, bringing new opportunities for the treatment of related diseases.
In the field of organic synthesis, it is an extremely important building block. With its own structural characteristics, it can participate in a variety of organic reactions, such as nucleophilic substitution, addition, etc., to build complex organic molecular structures and lay the foundation for the synthesis of organic materials with special functions. For example, in the field of optoelectronic materials, through clever design and synthesis, it is expected to prepare materials with unique optical and electrical properties.
In addition, in chemical biology research, it can be used as a probe molecule to explore specific biological processes and molecular mechanisms in vivo with the help of marking and tracking, providing a powerful tool for in-depth insight into the mysteries of life and promoting the continuous development of related disciplines.

(S )-( - )- N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinformamide is an organic compound. Its chemical properties are unique and have the following numbers:
- ** acidity and alkalinity **: The nitrogen atom in the molecule does not share a common electron pair, resulting in it being weakly basic and can form salts with acids. The carbonyl group in the amide group has a certain electron-withdrawing property, which makes the compound less basic than simple aliphatic amines. < Br > - ** Nucleophilic Substitution Reaction **: The carbonyl carbon of the amide group is electrophilic. When encountering nucleophilic reagents, such as alcohols, amines, etc., carbonyl oxygen can be attacked by nucleophilic reagents, and nucleophilic substitution reactions occur to generate new amides or esters.
- ** Hydrolysis Reaction **: Hydrolyzed under acidic or alkaline conditions. In acidic medium, protons first combine with amide carbonyl oxygen to enhance the electrophilicity of carbonyl carbon, and water attacks carbonyl carbon. Through a series of intermediates, isoquinoline formate acid and tert-butylamine salt are finally formed; under basic conditions, hydroxide attacks carbonyl carbon, and after intermediates, isoquinoline formate and tert-butylamine are formed. The rate and degree of hydrolysis depend on factors such as reaction temperature and acid-base concentration.
- ** Oxidation-reduction reaction **: If the nitrogen atom in the molecule is even hydrogen, it can be oxidized by an appropriate oxidant, resulting in a change in the valence state of the nitrogen atom; at the same time, the isoquinoline ring part is unsaturated and can be reduced under specific conditions, so that the unsaturated bond can be hydrosaturated < Br > - ** Ring-related Reactions **: Isoquinoline rings are aromatic and unsaturated, and electrophilic substitution reactions can occur, such as halogenation, nitrification, sulfonation, etc. The substitution position is affected by the electronic effect and spatial effect of the substituents on the ring. In addition, if the conditions in the molecule are suitable, the intramolecular cyclization reaction may occur to construct a new ring structure.

The synthesis of (S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide is an important matter in organic synthesis. The synthesis of this compound often involves multi-step reactions, and each step is carefully controlled to obtain the target product.
The first step may be to construct an isoquinoline parent nucleus. Usually, a suitable aramid and carbonyl compound is used, according to the principle of Pictet-Spengler reaction, under acid catalysis, condensation and cyclization to form an isoquinoline structure. This step requires attention to the ratio of reactants, reaction temperature and catalyst dosage. Due to subtle differences, the yield and selectivity of the reaction can change. < Br >
Next step, for the generated isoquinoline, hydrogenation reaction is carried out to obtain 1, 2, 3, 4-tetrahydroisoquinoline. In this process, it is crucial to select a suitable catalyst, such as palladium carbon, etc., to control the hydrogen pressure and reaction time. Improper conditions, or cause excessive hydrogenation, destroy the target structure.
Furthermore, the 3-position carboxyl group of tetrahydroisoquinoline is activated, or the acid chloride, acid anhydride and other reagents are used to convert it into an active acylation reagent. Afterwards, it reacts with tert-butyl amine to generate N-tert-butyl-1, 2, 3, 4-tetrahydro-3-isoquinoline formamide. In this acylation reaction, attention should be paid to the choice of reaction solvent to facilitate the dissolution and reaction of the reactants, and at the same time pay attention to the pH of the reaction system to prevent side reactions.
The whole process of synthesis, product separation and purification cannot be ignored. Column chromatography, recrystallization and other methods are used to remove impurities to obtain pure (S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinformamide to achieve the required purity standard.

I have not heard of (S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide in the market price geometry. However, if you want to know its price, you can explore it from many sources.
First, the chemical suppliers in the market often list the prices of various chemicals. When you look at their catalogues carefully, ask their sellers, or you can know the price of this product. Different suppliers, due to the source of goods, cost and other reasons, their prices may be different.
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Third, look at academic journals, research reports, or articles related to the preparation and use of this product, and occasionally mention the purchase price. Although the price is not real-time, it can also be used as a reference.
Fourth, negotiate with scholars and practitioners in the field of chemistry. They may be familiar with the market conditions of this product due to research and production needs, and can give an approximate price.
In conclusion, if you want to know the market price of (S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide, you can get a more accurate price when you compare it with many parties.

Today you ask (S) -（-) What is the manufacturer of -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide? This is involved in the field of fine chemicals. This compound is often used as a key intermediate in the research and production of pharmaceutical chemistry, and it plays an indispensable role in the synthesis of specific drugs.
Find its manufacturer. Among the domestic, there are several chemical reagents and pharmaceutical intermediates in Shanghai. With exquisite craftsmanship and cutting-edge technology, it has made outstanding achievements in the production field of this compound. They have a complete R & D and production system, which can be precisely customized according to customer needs, and the product quality is high, meeting various strict standards.
Furthermore, in Suzhou and Hangzhou, there are also companies specializing in high-end organic synthesis, which specialize in the production of this compound. They dig into the details of the process, guide green environmental protection and efficient output, optimize the production process, and have a good reputation in the industry.
Looking overseas, there are also many such manufacturers in Europe, America. There are companies in the United States that focus on the R & D and production of pharmaceutical intermediates. They have deep technical background and strong R & D strength. The (S) -（-) -N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline formamide has been widely praised in the global market. There are also chemical companies in Europe, Germany, France and other places involved in this field, supplying high-quality products with rigorous craftsmanship and innovative concepts.
All of these, many domestic and foreign manufacturers have developed their strengths in the production of this compound to meet the diverse needs of scientific research and industry.