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What is the chemical structure of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic acid?
This is the chemical structure analysis of (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, and it is described in the classical Chinese genre of Tiangong Kaiwu.
This compound, according to its name, contains a quinoline parent nucleus. Quinoline is an important heterocyclic compound with a unique conjugate structure. On the framework of 1,4-dihydro-quinoline, the 4-position is a carbonyl group (ie, 4-oxo). The existence of this carbonyl group gives the molecule a specific electron cloud distribution and chemical activity.
The introduction of fluorine atoms at the 7 position has strong electronegativity. The introduction of fluorine can significantly affect the electron cloud density of the molecule and change the physical and chemical properties of the compound, such as lipophilicity and stability. The 6-position iodine atom is connected, and the iodine atom has a large radius, which also affects the spatial structure and reactivity of the molecule. The
1 position is connected with a substituent of 1-hydroxymethyl-2-methyl-propyl. This substituent contains hydroxymethyl and methyl. Hydroxymethyl is hydrophilic and can participate in the formation of hydrogen bonds; methyl is the power supply group, which affects the electron cloud distribution of molecules. The 3 position has a carboxyl group, which is acidic and can participate in acid-base reactions. It plays an important role in the solubility and biological activity of the compound.
In summary, the chemical structure of this compound is composed of a quinoline parent nucleus and many specific position substituents. The interaction of each part endows the compound with unique physicochemical and biological activity characteristics.
What are the physical properties of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic acid?
(S) - 7 - fluoro - 1 - (1 - hydroxymethyl - 2 - methylpropyl) - 6 - iodine - 4 - oxo - 1, 4 - dihydroquinoline - 3 - carboxylic acid, this is an organic compound. Its physical properties are particularly important, related to its performance in various chemical processes and practical applications.
Looking at its morphology, it often takes a crystalline solid state at room temperature and pressure. This morphology is easy to store and transport, and its crystalline structure endows it with relatively stable physical properties. Its melting point is also a key physical property, which is about a specific temperature range. This temperature has a great impact on its purification and processing process. If you want to treat it by heating, you must carefully control the temperature to prevent it from melting above the melting point and causing changes in morphology and properties.
In terms of solubility, it shows a certain solubility in common organic solvents, such as ethanol and dichloromethane. In ethanol, moderate heating can promote its dissolution to form a uniform solution. This solubility makes it convenient to participate in many organic synthesis reactions, because most organic reactions can be carried out efficiently in a solution environment. In water, its solubility is relatively limited. This property is related to the presence of hydrophobic groups in the molecular structure, which hinder the effective interaction between molecules and water molecules.
Furthermore, the compound has a certain density. This density value is within a specific range and is indispensable in chemical operations involving mass and volume conversion. For example, when preparing a solution of a specific concentration, the density is precisely known in order to accurately measure the amount of the desired substance.
Its refractive index also has a specific value. The refractive index reflects the degree to which the direction of light changes when passing through the substance. This property can be used as an important basis for identification in the field of analytical chemistry, especially in purity detection and composition analysis.
To sum up, (S) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acids have many physical properties, such as morphology, melting point, solubility, density, and refractive index, which are of great significance to their chemical research and practical application. Chemists must consider these properties in detail when operating and studying this compound.
What are the synthesis methods of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic acid?
The synthesis of (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid is a crucial issue in the field of organic synthesis. The structure of this compound is delicate and complex, and the synthesis process is also full of challenges.
To synthesize this compound, a common method is to use a suitable quinoline derivative as the starting material. First, the quinoline parent nucleus is modified, and fluorine atoms and iodine atoms are introduced at specific positions. The halogenation reaction can be used to carefully adjust the reaction conditions to precisely locate the fluorine and iodine atoms. For example, in an appropriate catalyst and solvent system, an electrophilic substitution reaction is used to cleverly combine the fluorine source and iodine source with the quinoline parent nucleus.
Second, the key side chain of 1- (1-hydroxymethyl-2-methyl-propyl) is constructed. It can be achieved through a multi-step reaction. First, a suitable aldehyde, ketone and other compounds are used as raw materials, and a carbon chain skeleton is constructed through a reaction such as hydroxyaldehyde condensation, and then a hydroxymethyl group is introduced through a reaction such as reduction.
Third, synthesize 4-oxo-1,4-dihydro-quinoline-3-carboxylic acid moiety. Or through cyclization reaction, the parts constructed in the previous stage can be cleverly connected to form the basic structure of the target compound. During the reaction process, the reaction temperature, pH and other conditions need to be strictly controlled to ensure that the reaction proceeds according to the expected path and improve the yield and purity of the product.
Although the synthesis methods have their own advantages, they all require fine operation and insight into the reaction conditions to successfully prepare (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid.
(S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic acid is used in what areas?
(This compound) (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, has applications in many fields such as medicine and chemical industry.
Looking at the structure of this compound, its unique molecular structure endows it with various chemical activities. In the field of medicine, due to the specific combination of groups in the structure, it may exhibit antibacterial activity. Quinoline carboxylic acids are often an important structural basis for antibacterial drugs. The introduction of fluorine, iodine and other atoms in this compound may regulate its interaction with bacterial targets, enhance antibacterial effects, and may have potential applications in the treatment of bacterial infections.
In the chemical industry, as an organic synthesis intermediate, it can participate in many chemical reactions by virtue of its own activity check point to construct more complex organic molecular structures. Through its reaction with other organic reagents, it can synthesize materials with special properties, such as for the modification of polymer materials, endowing materials with new physical and chemical properties, such as improving the stability and solubility of materials, so as to expand the application range of polymer materials in different fields. In summary, the application of this compound in the fields of medicine, chemical industry, etc., may bring new development opportunities for related fields and promote technological and product innovation.
What is the market outlook for (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic acid?
(S) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, which is a rather unique class of compounds. In today's market environment, it presents a multi-faceted trend.
In the field of Guanfu Pharmaceutical R & D, such quinoline carboxylic acid compounds containing specific structures often have potential pharmacological activities such as antibacterial and antiviral activities. In recent years, the demand for new anti-infective drugs is increasing day by day, and the rampage of drug-resistant bacteria has made it urgent to search for more efficient and unique antimicrobial agents. ( If S) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acid can exhibit excellent antibacterial activity and has a good inhibitory effect on drug-resistant bacteria, it is very likely to become the focus of the development of new antibacterial drugs, and the market prospect is quite promising.
However, it also faces challenges. Synthesis of such compounds may require complex processes and high costs, which will affect their large-scale preparation and marketing activities. And the research and development of new drugs requires long clinical trials to ensure their safety and effectiveness. This process is time-consuming, laborious and costly.
In the chemical industry, it may be used as a special intermediate for the synthesis of more complex organic compounds. With the vigorous development of the fine chemical industry, the demand for characteristic intermediates is increasingly diverse. If the compound can exhibit unique reactivity and selectivity in the chemical synthesis path, providing a new way for the preparation of chemicals with specific structures and functions, it can also find a place in the chemical market.
However, the chemical industry is highly competitive and needs to compete for market share with other similar or alternative intermediates. Therefore, in order to expand the market, it is necessary to highlight advantages in performance, cost and supply stability.
In summary, (S) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acid faces challenges, but there are potential opportunities in the fields of medicine and chemical industry. If the problem can be properly addressed, it is expected to emerge in the market.