(S) What is the chemical structure of -4-Ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12, 14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-3,14-dione
This is the chemical nomenclature of a thing. If you want to clarify its chemical structure, please listen to me in detail.
The name of this compound is long and complicated, and it is analyzed according to the organic chemistry nomenclature. " (S) -4-Ethyl-4-hydroxy -", this part indicates that in a specific configuration (S configuration), ethyl is connected to hydroxyl at position 4. "11- [2- (isopropylamino) ethyl] -" shows that position 11 is connected to ethyl containing isopropylamino.
Furthermore, "3,4,12,14 - tetrahydro - 1H - pyrano [3 ', 4': 6,7] indolizino [1,2 - b] quinoline - 3,14 - dione" This section reveals its core skeleton structure. Consists of multiple fused cyclic structures, including tetrahydropyran rings and indolisidine-quinoline structures, and has two carbonyl groups at positions 3 and 14.
The chemical structure of this compound is like a carefully constructed chemical castle. The core fused ring system is the cornerstone, on which different substituents are connected at specific positions according to the naming convention. Ethyl and hydroxyl are like unique decorations on the city walls, while isopropylaminoethyl is like a special channel extending out, and the parts cooperate to form this complex and unique chemical structure. In this way, the chemical structure of " (S) -4-Ethyl-4-hydroxy-11 - [2- (isopropylamino) ethyl] - 3,4,12,14 - tetrahydro - 1H - pyrano [3 ', 4': 6,7] indolizino [1,2 - b] quinoline - 3,14 - dione" is roughly clarified.
(S) What are the physical properties of -4-Ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12, 14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-3,14-dione
(2S) -4-ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14-dione, this is a complex organic compound. In terms of physical properties, it may be in solid form at room temperature and pressure. Due to the strong intermolecular force of this class of compounds containing polycyclic and complex substituents, it is often in a solid state. Looking at its structure, it contains multiple cyclic structures and various functional groups, which makes it have a certain melting point. However, the specific value is difficult to determine due to the lack of experimental data. Usually, compounds containing many conjugated systems and heteroatoms have a higher melting point. < Br >
In terms of solubility, considering that it contains polar hydroxyl and amino groups, it may have certain solubility in polar solvents such as water and alcohol. However, the large non-polar polycyclic structure in the molecule limits its solubility in water, and its solubility is better in organic solvents such as methanol and ethanol.
Its density is also difficult to accurately express due to the lack of experimental data. According to the structure, it is speculated that the density may be greater than that of water because the atoms such as carbon, hydrogen, oxygen and nitrogen in the molecule form a compact structure.
The physical properties of this compound are influenced by its unique molecular structure. The polycyclic system endows it with stability and specific physical morphology, and the properties of functional groups determine its solubility and some other physical properties. With the deepening of research, more accurate physical property data may be clear.
(S) what is the main use of -4-Ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3, 4, 12, 14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-3,14-dione
(This is the chemical substance (2S) -4-ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14-dione, but there is no such thing in ancient times, so the following is a description of the text of its fictional use)
(2S) -4-ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14-dione, this is strange Things are also. In ancient times, although there was no such exact thing, it might be useful if it was imagined.
Looking at its structure, it is exquisite and complicated, or it can be used for healing diseases. Ancient healers often sought various medicines to cure the diseases of the people. If this thing exists, or because of its unique nature, it can enter the meridians and regulate qi and blood. Its hydroxyl, amino and other groups may be able to resist the diseases and evils in the body. In case of stagnation of qi and blood, with its delicate structure, it may be able to dredge the veins and make qi and blood flow smoothly, like the water of a river, remove its congestion and restore its smoothness.
Furthermore, it may also be possible for the way of health. The ancient people emphasized health preservation, seeking the method of longevity and long-term vision. This thing may be able to replenish the essence, cultivate the essence and strengthen the foundation. Its special ingredients may stimulate vitality in the body and make the viscera function healthy and prosperous. Like the spring breeze and rain, it nourishes all things, makes the body healthy and clear, and prolongs life, or it can be expected.
Or it can be used for alchemy. The ancient alchemists were keen on alchemy, hoping to achieve the extraordinary state of the elixir. The strangeness of this thing may become the essential medicine for alchemy, integrate it into all kinds of gold and stone things, refine the elixir, and serve it or be reborn and become a saint. Although it is an imagination, it is a possible use for the pursuit at that time.
(S) What are the synthetic methods of -4-Ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12, 14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-3,14-dione
To prepare (S) - 4 - ethyl - 4 - hydroxy - 11 - [2 - (isopropylamino) ethyl] - 3,4,12,14 - tetrahydro - 1H - pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline - 3,14 - dione, the synthesis method is quite complicated, and it needs to be advanced step by step according to the exquisite organic synthesis method.
At the beginning, a compound containing indolicidine structure can be selected as the starting material. This raw material has been carefully designed and processed to lay the foundation for subsequent reactions. The first step is to make the starting material and a specific halogenated alkane hydrocarbon in a suitable solvent, catalyzed by a base, and perform nucleophilic substitution reaction. The selection of halogenated alkanes needs to meet the structural requirements of the target product, and ethyl groups such as ethyl groups are precisely introduced. The control of this reaction condition is crucial. The polarity of the solvent, the strength and dosage of the base will all affect the process and yield of the reaction.
Then, for the introduced group, hydroxylation is performed. This step can be achieved by oxidation. For example, a suitable oxidizing agent is selected to convert the specific carbon-hydrogen bond into a hydroxyl group under mild reaction conditions. There are many kinds of oxidizing agents, which should be carefully selected according to the characteristics of the substrate and the selectivity of the reaction. And during the reaction process, care should be taken to avoid excessive oxidation, so as not to damage other structures of the molecule.
As for the key part of introducing 11- [2- (isopropylamino) ethyl], it can be gradually constructed through a multi-step reaction. First, the specific position of the molecule is activated with a suitable reagent, and then it is reacted with a reagent containing isopropylamino ethyl structure. In this process, various reaction mechanisms such as nucleophilic addition and condensation are involved. The optimization of reaction sequence and conditions is related to the purity and yield of the final product.
When constructing the structure of pyrano and quinolinedione, intracolecular cyclization reactions are required. By adjusting the pH, temperature and other conditions of the reaction system, the molecules are cyclized to form a specific cyclic structure of the target product. This cyclization reaction is the core step of synthesis, and precise control of various parameters is required to ensure the smooth progress of cyclization and obtain the ideal product.
After each step of the reaction, it is necessary to use separation and purification methods such as column chromatography and recrystallization to remove impurities and improve the purity of the product. In this way, the complex structure of (S) -4-ethyl-4-hydroxy-11- [2 - (isopropylamino) ethyl] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14-dione can be obtained by carefully designing and manipulating the reaction in multiple steps.
(S) -4-Ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12, 14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-3,14-dione What are the relevant pharmaceutical applications
(This compound) is named (2S) -4-ethyl-4-hydroxy-11- [2- (isopropylamino) ethyl] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolo [1,2-b] quinoline-3,14-dione. However, I have searched ancient and modern pharmacopoeias, although I have not heard of a definite pharmaceutical application that fully matches the name of this compound.
Looking at its structure, it contains a polycyclic system and a variety of functional groups, or has unique pharmacological activities. Or it can be speculated that it has polar groups such as hydroxyl and amino groups, or affects their interaction with biological macromolecules, in the field of drug development, or is a potential lead compound.
Hydroxyl groups can participate in the formation of hydrogen bonds and help them bind specifically to receptors. The introduction of isopropylamino groups may change the lipophilicity of compounds, affecting their transmembrane transport and binding to protein hydrophobic pockets. Polycyclic structure endows it with rigidity, or is essential for the selectivity and affinity of receptor binding.
Although it has not been seen for specific drug applications, it may be used to develop drugs for neurological diseases according to modern medicinal chemistry theory, because polycyclic indole structures often have neuroactivity. Or for the development of anticancer drugs, some compounds containing quinolinodione structures have shown anti-cancer potential. This compound may inhibit the proliferation of cancer cells due to its unique structure binding to active check points.
In summary, although the exact drug use has not been heard today, its structural characteristics suggest that it has potential value in many fields of drug development, which will be further explored by future doctors and medicine practitioners.