What is the chemical structure of (R) -1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrol isoquinoline hydrochloride?
What is the chemical structure of (R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthoyl isobutyric anhydride?
In order to clarify the chemical structure of this substance, it is necessary to analyze the names of its parts. " (R) " means that its stereochemical configuration is R-type, which is related to the specific arrangement of atoms or groups in the molecule in space. "1,2,3,4-tetrahydro" shows that the 1, 2, 3, and 4 positions of this naphthalene ring (naphthalene is a fused ring aromatic hydrocarbon) undergo hydrogenation, that is, one part of the naphthalene ring obtains hydrogen and becomes a single bond, which changes from an aromatic ring structure to a ring system with partially saturated characteristics.
"6,7-diethoxy" means that the 6th and 7th positions of the ring system are each connected with an ethoxy group (-O-C -2 H), which is a substituent containing ethyl and oxygen atoms. "1-naphthoyl" refers to the naphthoyl group attached to the 1st position, which is a group formed by connecting the naphthalene ring with a formyl group (-CO-). "Isobutyric anhydride", its basic structure is the acid anhydride structure obtained by removing a molecule of water from two isobutyric acid molecules, with the characteristic functional group of acid anhydride - CO - O - CO -.
Overall, this compound is based on a hydrogenated naphthalene ring, modified with ethoxy at the 6th and 7th positions, and naphthalenyl at the 1st position. It is connected to the isobutyric acid-derived part through acid anhydride bonds to form a specific chemical structure. Each part is connected to each other to form a unique molecular structure of (R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthalenyl isobutyric anhydride.
What are the main physical properties of (R) -1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrol isoquinoline hydrochloride?
(R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthoyl isobutyrate lactone is an organic compound, and its main physical properties are as follows:
In terms of appearance, this compound is often in a solid state, and its color may be white to off-white. This is due to the arrangement and interaction of atoms in the molecular structure, resulting in such an appearance of light reflection.
In terms of melting point, due to the intermolecular force, it is about a certain temperature range (the specific value varies depending on the precise measurement conditions). At this temperature, the molecule obtains enough energy to overcome the lattice energy, the lattice structure disintegrates, and the substance changes from a solid state to a liquid state.
In terms of solubility, due to the fact that there are both polar and non-polar parts in the molecule, in organic solvents such as ethanol and dichloromethane, it exhibits a certain solubility by virtue of the interaction between Van der Waals force and hydrogen bonds between the solvent molecules. In water, the solubility is poor due to the weak interaction between water molecules and the compound molecules.
Density is also an important physical property, which is determined by the molecular weight and the degree of molecular accumulation. It has a specific value under specific conditions, reflecting the mass of the substance per unit volume.
In addition, the compound may have a specific refractive index, which is due to the refractive properties of its molecules to light, which is related to the electron cloud distribution and chemical bond properties of the molecule, and can be used for identification and purity analysis. The above physical properties are all due to the unique molecular structure of the compound and the interaction between atoms, which is of great significance for its application in organic synthesis, drug development and other fields.
What are the preparation methods of (R) -1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrol isoquinoline hydrochloride?
To prepare (R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthalenyl isobutyrate lactone, the method is as follows:
First take an appropriate amount of naphthalene derivatives as starting materials. This raw material needs to have a specific substituent structure in order to facilitate subsequent reactions. Dissolve the naphthalene derivative in a suitable organic solvent, and adjust the temperature of the reaction system to a specific range, usually in the low temperature range, to prevent side reactions from occurring.
Then, slowly add a halogenating reagent to halogenate the naphthalene ring at a specific position to form a halogenated naphthalene intermediate. This process requires precise control of the amount of reagents and reaction time to ensure that the reaction is sufficient and not excessive. < Br >
Next, an ethoxylation reagent is added to the reaction system. Under the catalytic action of the base, the ethoxylation reaction of the halogenated naphthalene intermediate is promoted, and the diethoxylation group is introduced. When reacting, attention should be paid to the type and dosage of the base, as well as the control of the reaction temperature and time, to ensure the smooth progress of the ethoxylation reaction.
Then, with the help of a suitable reducing agent, the reduction reaction is carried out on the naphthalene derivative containing the diethoxy group, so that the naphthalene ring can be partially reduced to form a tetrahydronaphthalene structure, and the tetrahydro-diethoxylated naphthalene intermediate is obtained.
Then an acylation reagent is introduced, so that the intermediate reacts with the acylation reagent under In this step, the activity and selectivity of the acylating reagent need to be considered to avoid unnecessary side reactions.
Finally, the lactone structure is constructed through cyclization. Appropriate catalysts and reaction conditions can be used to promote the cyclization reaction in molecules to achieve the preparation of (R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthyl formyl isobutyric acid lactone. During the preparation process, the reaction products need to be separated and purified in each step to ensure the purity and quality of the products.
What are the applications of (R) -1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrol isoquinoline hydrochloride in the field of medicine?
(R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthoyl isobutyrate naphthyl ester is used in the field of medicine and is mostly used to create new drugs. Its application is outlined below:
First, it plays a role in the development of drugs for nervous system diseases. Because of its unique chemical structure and three-dimensional configuration, it may regulate the release and transmission of neurotransmitters. For Parkinson's disease, this compound may affect dopamine secretion and nerve cell signaling, laying the foundation for the development of specific therapeutic drugs. And it can protect and repair nerve cells, or help treat neurodegenerative diseases such as Alzheimer's disease, by preventing nerve cell damage, promoting nerve regeneration, and improving patients' cognitive and behavioral ability.
Second, it has emerged in the development of cardiovascular disease drugs. It can act on specific targets of the cardiovascular system and regulate cardiac electrophysiological activities. It can optimize myocardial contractility and treat heart failure; or it can regulate vascular tone, which is beneficial for the treatment of hypertension. By dilating blood vessels, it reduces peripheral resistance and stabilizes blood pressure.
Third, it has potential in the development of anti-tumor drugs. Or it can inhibit the proliferation of tumor cells and induce their apoptosis. By acting on key molecules of tumor cell signaling pathways, blocking tumor growth and diffusion signaling, it can also enhance tumor cells' sensitivity to chemotherapy drugs, improve chemotherapy effect, and reduce drug resistance.
Fourth, it has potential value in anti-inflammatory immunomodulatory drugs. It may regulate the function of immune system cells and inhibit the release of inflammatory factors. For autoimmune diseases such as rheumatoid arthritis, it can reduce inflammatory response, relieve joint pain and swelling, and improve patients' quality of life.
What are the market prospects for (R) -1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrol isoquinoline hydrochloride?
(R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthoyl isobutyrate lactone, which is a specific organic compound. When it comes to the market prospects of this product, it can be viewed from the following aspects.
First, in the field of medicine, many organic compounds with specific structures are the key to innovative drug development. If this compound is confirmed to have unique biological activities by research, such as significant effects on specific disease targets, it may become a lead compound for new drugs. Based on the experience of many successful drug development in the past, if its pharmacological effects can be accurately positioned and subsequently optimized, it is very likely to develop innovative drugs with excellent efficacy, and the market demand will be considerable at that time.
Second, in the field of materials science, some organic compounds can exhibit unique optical, electrical and other properties after special treatment. If this compound can act as a key raw material in material synthesis and endow the material with special properties, such as improving material stability and enhancing its optical properties, it will have broad application space in the high-end material market.
However, there are also some challenges. The complexity of the synthesis process is a major problem. If the synthesis steps are cumbersome and costly, it will greatly limit its large-scale production and marketing activities. And market competition should not be underestimated. Compounds with similar structures or functions may already exist in the market, and they need to highlight their advantages in performance and cost in order to be favored by the market.
To sum up, (R) -1,2,3,4-tetrahydro-6,7-diethoxy-1-naphthoyl isobutyrate lactone has opportunities and challenges in the market, and its performance and application need to be further studied to optimize the synthesis process in order to develop the market.