Quinoline 7 Carboxylic Acid
quinoline thiophene imidazole thiazole

Quinoline-7-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    146942

    Chemical Formula C10H7NO2
    Molar Mass 173.17 g/mol
    Appearance Solid
    Melting Point 255 - 258 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Pka Value Around 4.8 - 5.0 (approximate for the carboxylic acid group)
    Color Off - white to light yellow
    Odor Odorless or very faint odor
    Crystal Structure Typically forms needle - like crystals

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    General Information
    Where to Buy Quinoline-7-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading Quinoline-7-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Quinoline-7-carboxylic acid?
    Quinoline-7-carboxylic acid is one of the organic compounds. It has a wide range of main uses and is of great significance in many fields.
    In the field of medicinal chemistry, quinoline-7-carboxylic acid is often a key intermediate in the synthesis of many drugs. Because of its unique chemical structure, it can interact with specific targets in organisms. For example, using this as a starting material, through a series of delicate chemical reactions, drugs with antibacterial and anti-inflammatory effects can be prepared. Because of its structure, it can precisely fit pathogens or inflammation-related targets, thus exhibiting good pharmacological activity and helping the human body fight diseases.
    In the field of materials science, quinoline-7-carboxylic acids also have their uses. They can be used to prepare functional materials, such as luminescent materials. By chemically modifying and assembling them, the optical properties of the materials can be regulated, so that they can play a role in optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), improve the luminous efficiency and stability of the devices, and provide support for the research and development of new optoelectronic devices.
    In addition, in the field of organic synthetic chemistry, quinoline-7-carboxylic acids are an important synthetic building block and participate in the construction of many complex organic molecules. By ingeniously designing reaction pathways and using their unique functional group characteristics, chemists have created a variety of novel organic structures, expanded the types and functions of organic compounds, and contributed to the development of organic chemistry.
    What are the physical properties of Quinoline-7-carboxylic acid?
    Quinoline-7-carboxylic acid is a kind of organic compound. Its physical properties are unique and of great research value.
    Looking at its appearance, under room temperature and pressure, quinoline-7-carboxylic acid is in a solid state. Its color is usually off-white to light yellow, with a warm color. The appearance of this color is derived from the interaction of atoms in its molecular structure and the distribution of electron clouds.
    When it comes to melting point, the melting point of quinoline-7-carboxylic acid is about 185-189 ° C. The determination of melting point requires precise experimental equipment and rigorous operation procedures. In this temperature range, the intermolecular force changes, the lattice structure gradually disintegrates, and the substance gradually changes from solid to liquid.
    Solubility is also an important physical property. The solubility of quinoline-7-carboxylic acid in water is very small, because the polarity of this compound is relatively weak, and the interaction force with water molecules is difficult to overcome the hydrogen bond between water molecules. However, in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), its solubility is relatively high. The molecular structure and polarity of organic solvents can be compatible with quinoline-7-carboxylic acids, and their dissolution is promoted by intermolecular forces, such as van der Waals force and dipole-dipole interaction.
    In addition, the density and vapor pressure of quinoline-7-carboxylic acids are also affected by their molecular structure and intermolecular forces. The density value reflects the distribution of molecules in a unit volume, while the vapor pressure is related to its tendency to change from liquid or solid to gas at a certain temperature. However, the exact values of these two need to be determined under specific experimental conditions by professional experimental equipment.
    The above physical properties have important guiding significance for understanding the chemical behavior of quinoline-7-carboxylic acids, participating in chemical reactions, and applications in pharmaceutical chemistry, materials science, and other fields.
    What are the synthetic methods of Quinoline-7-carboxylic acid?
    The synthesis method of quinoline-7-carboxylic acid has been known for a long time, and it has undergone evolution, and various approaches can be achieved.
    First, suitable aromatic amines and carboxylic acid derivatives with specific structures are used as starting materials, and the journey is started through condensation reaction. For example, an aromatic amine and a halogenated aromatic hydrocarbon containing carboxyl groups are condensed under suitable catalysts and reaction conditions. In this process, the choice of catalyst is very critical. It is necessary to carefully select metal salts or organic bases catalysts according to the characteristics of the reactants, and the temperature and solvent also need to be precisely regulated. If the temperature is too high or too low, the reaction can be biased to the side way, and the polarity and solubility of the solvent also have a great impact on the reaction process and yield.
    Second, the skeleton of quinoline-7-carboxylic acid is constructed by cyclization reaction. First, appropriate substitutions of benzene ring compounds and nitrogen-containing heterocyclic precursors are used to achieve intramolecular cyclization through carefully designed reaction steps. This cyclization reaction may require the excitation of light, heating and other conditions to rearrange and close the chemical bonds in the molecule, and then form the basic structure of quinoline. Subsequent carboxylation is modified, and carboxyl groups are introduced at specific positions to obtain the target product. However, in this path, the selectivity of cyclization check points and the accuracy of carboxylation require ingenious reaction design and optimization of conditions to achieve expectations.
    Third, natural products are used as starting materials and converted by chemical modification. There are many natural products with quinoline-like structures in nature. Carboxyl groups can be introduced at specific positions through a series of chemical transformations, such as oxidation and substitution, using their inherent skeleton. Although this method has the potential for green chemistry due to natural sources of raw materials, the acquisition and purification of natural products are often challenging, and the selectivity and efficiency of subsequent chemical modifications also need to be carefully considered.
    All kinds of synthesis methods have their own advantages and disadvantages. In fact, the choice needs to be weighed according to factors such as actual demand, availability of raw materials, cost considerations, and expected purity in order to achieve the optimal synthesis strategy.
    Where is Quinoline-7-carboxylic acid used?
    Quinoline-7-carboxylic acids are useful in various fields. In the field of medicine, this compound is often a key raw material for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, or have antibacterial, anti-inflammatory, and anti-tumor effects. For example, through delicate synthesis and modification, targeted drugs for specific cancer cells may be developed, which can precisely act on key signaling pathways of cancer cells, inhibit their growth and spread, and open up new avenues for anti-cancer treatment.
    In the field of materials science, quinoline-7-carboxylic acids also have extraordinary performance. Can be used to prepare materials with special functions, such as luminescent materials. After proper molecular design and assembly, it can emit a unique spectrum under specific conditions, making it stand out in display technology, fluorescence sensing, etc. In fluorescence sensing, it can produce a sensitive response to specific substances or environmental factors, and can be indicated by the change of fluorescence signal to achieve rapid and accurate detection of the target.
    Furthermore, in the field of organic synthesis chemistry, quinoline-7-carboxylic acids, as an important organic synthesis intermediate, can participate in the construction of many complex organic molecules. With its activity check point, chemists use a variety of organic reactions, such as nucleophilic substitution, oxidation and reduction, to synthesize organic compounds with novel structures and unique functions, enrich the types of organic compounds, and contribute to the development of organic chemistry. All these show that quinoline-7-carboxylic acids are widely used in medicine, materials, organic synthesis and other fields, and are actually very valuable chemical substances.
    What is the market outlook for Quinoline-7-carboxylic acid?
    Quinoline-7-carboxylic acid, which is an important compound in organic chemistry. Looking at its market prospects, there are many things to be said.
    In the field of medicine, its prospects are quite good. Today, various diseases are in high demand for new drugs, and quinoline-7-carboxylic acid, as a key intermediate, can pave the way for the creation of specific drugs. Numerous studies have focused on the research and development of drugs containing quinoline structures. Due to its unique chemical structure, it gives drugs potential biological activities, such as antibacterial, anti-inflammatory, and anti-tumor. Therefore, in the pursuit of innovative drugs in the pharmaceutical industry, the market demand for quinoline-7-carboxylic acid is expected to rise steadily.
    The field of pesticides cannot be ignored. With the process of agricultural modernization, there is a growing demand for high-efficiency and low-toxicity pesticides. Quinoline-7-carboxylic acid may emerge in the creation of pesticides. With its structural characteristics, targeted and environmentally friendly pesticide products have been developed to meet the needs of agricultural production for green and safe pesticides. Its application prospects in the pesticide market are quite broad.
    Furthermore, scientific research and exploration continue to expand. The continuous improvement of chemical synthesis technology has brought new opportunities for the preparation of quinoline-7-carboxylic acid. The production cost may be optimized, and the product quality is also expected to improve. This will further enhance its competitiveness in the market, attract more scientific researchers to explore its application potential in depth, and thus promote the gradual expansion of the market scale.
    However, the road ahead for the market is not smooth. The chemical industry is highly competitive, with many similar or alternative products competing for the market. To stand out, quinoline-7-carboxylic acid needs to make unremitting efforts in technological innovation and cost control. Only in this way can it occupy a place in the unpredictable market and enjoy the dividends of future development.