Quinoline 4 Chloro 6 Fluoro
quinoline thiophene imidazole thiazole

Quinoline, 4-chloro-6-fluoro-

Taiy Chemical

    Specifications

    HS Code

    716857

    Chemical Formula C9H5ClFN
    Molecular Weight 183.59
    Appearance Solid (usually)
    Solubility In Water Low (expected, due to non - polar nature of aromatic ring)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (expected)
    Logp Positive (hydrophobic, due to aromatic structure)

    As an accredited Quinoline, 4-chloro-6-fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive Quinoline, 4-chloro-6-fluoro- prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy Quinoline, 4-chloro-6-fluoro- in China?
    As a trusted Quinoline, 4-chloro-6-fluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Quinoline, 4-chloro-6-fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 4-chloro-6-fluoroquinoline?
    4-Xenon-6-radon square light has special foreign physical properties. Xenon is a colorless and odorless inert gas. Its density is higher than that of air, about 5.89kg/m ³ under standard conditions. The melting point is -111.9 ° C, and the boiling point is -108.1 ° C. Xenon is extremely inactive, but under special conditions, it can also form compounds, such as xenon hexafluoroplatinate. This is the first rare gas compound prepared by humans, breaking the understanding that rare gases are "absolutely inert" in the past.
    As for 6-radon square light, radon gas is actually radon. Radon is also a colorless and odorless inert gas with a very high density of about 9.73kg/m ³, one of the densest known gases. The melting point of radon is -71 ° C and the boiling point is -61.8 ° C. Radon is radioactive and is a product of the decay of radioactive elements such as radium and thorium. When it decays, it emits alpha particles. This property is used in fields such as medicine and geological exploration.
    Both can be liquefied at extremely low temperatures. And because of its inert nature, it can be used as a protective gas in certain environments. However, the radioactivity of radon needs to be treated with caution. Its accumulation in indoor environments can greatly increase the risk of lung cancer. Although xenon is non-radioactive, it can emit a strong glow under conditions such as high voltage and strong electric field, and is often used in lighting fields, such as xenon headlamps, which have high luminous efficiency and bright light.
    What are the chemical properties of 4-chloro-6-fluoroquinoline?
    4-Alkane-6-alkenyl ether light is a genus of organic compounds with unique chemical properties and is widely used in many fields. Its chemical properties are as follows:
    First, it has the reactivity of unsaturated bonds. 6-alkenyl groups contain carbon-carbon double bonds with active properties. Addition reactions can occur, such as addition to halogen elementals (chlorine, bromine, etc.), and halogen atoms are directly added to the carbon atoms at both ends of the double bond to form corresponding halogenated hydrocarbons. Taking bromine as an example, the reaction is as follows: R-CH = CH-R ' (the alkenyl part of the photostructure of 4-alkane-6-alkenyl ethers) + Br ² → R-CHBr-CHBr-R'. This reaction is mild and can be carried out at room temperature, pressure and in a suitable solvent. At the same time, it can also be added to hydrogen halide, following the Markov rule, hydrogen atoms are added to carbon atoms containing more hydrogen double bonds, and halogen atoms are added to carbon atoms containing less hydrogen double bonds.
    Second, the characteristics of ether bonds. The ether bond (C-O-C) in 4-alkyl-6-alkenyl ether light is relatively stable, but it can be broken under certain conditions such as strong acid or high temperature. In the case of concentrated hydroiodic acid (HI), the ether bond will cleave, resulting in the formation of corresponding alcohols and iodohydrocarbons. For example: R-O-R ' (ether bond part) + HI → R-OH + R' -I. This is due to the strong nucleophilicity of iodine ions in hydroiodic acid, which attacks the ether bond carbon atom and causes the ether bond to break.
    Third, photochemical reactivity. Because its name contains "light", it implies that it is sensitive to light and can undergo photochemical reactions. Under the irradiation of light of a specific wavelength, the molecule absorbs light energy and jumps to the excited state, which then triggers a series of reactions. If intramolecular rearrangement may occur, products with different structures will be generated; or photoaddition and photosubstitution reactions will occur with other molecules. This photochemical reaction property makes it have important applications in the fields of photoinitiated polymerization and photocatalytic synthesis.
    Fourth, oxidation reaction. 6-alkenyl double bonds are easily oxidized, and common oxidants such as potassium permanganate (KMnO) and ozone (O 🥰) can react with them. Oxidation with a cold, dilute and basic potassium permanganate solution results in the formation of an o-glycol structure at the double bond; if oxidized with an acidic potassium permanganate solution or ozone, the double bond will break and produce the corresponding aldehyde, ketone or carboxylic acid. The specific product depends on the structure.
    What are the common synthesis methods of 4-chloro-6-fluoroquinoline?
    The common synthesis methods of 4-bromo-6-hydroxybenzoic acid are as follows:
    ** 1. Hydrolysis method with 4-bromo-6-methoxybenzoic acid as raw material **
    Take a certain amount of 4-bromo-6-methoxybenzoic acid and place it in a reactor, add an appropriate amount of concentrated hydrobromic acid, heat it up to 120-130 ° C, and reflux at this temperature for 8-10 hours. During the reaction, the methoxy group will be hydrolyzed under the action of hydrobromic acid and converted into a hydroxyl group. After the reaction is completed, the reaction liquid is cooled, and then slowly poured into a large amount of ice water, and solids are precipitated. The solid is filtered, collected, washed several times with water to remove impurities, and then recrystallized with ethanol to obtain pure 4-bromo-6-hydroxybenzoic acid. This method is relatively simple to operate, and the raw materials are easy to obtain. However, the reaction requires a high temperature, and the concentrated hydrobromic acid is corrosive, so caution is required during operation. < Br >
    ** Second, the protection-bromination method with 2-bromo-4-carboxyphenol as raw material **
    First, 2-bromo-4-carboxyphenol and an appropriate amount of tert-butyl-dimethylchlorosilane (TBDMSCl), imidazole into N, N-dimethylformamide (DMF) solvent, stirred at room temperature for 4-6 hours, so that the phenolic hydroxyl group is protected and the corresponding silicon ether protection product is generated. After that, transfer this protective product to another reaction vessel, add an appropriate amount of liquid bromine and catalyst (such as iron powder), react at low temperature (0-5 ° C) for 2-3 hours to realize bromination reaction, and introduce bromine atoms at specific positions in the benzene ring. After the reaction is completed, add an appropriate amount of tetrabutylammonium fluoride (TBAF) tetrahydrofuran solution to the system, stir at room temperature for 3-4 hours to remove the silicon ether protective group and restore the hydroxyl group. Finally, 4-bromo-6-hydroxybenzoic acid can be obtained by extraction, concentration, column chromatography and other operations. This method has many steps, but the reaction conditions are relatively mild and the selectivity is good, which can effectively control the bromination position.
    ** III. Stepwise Synthesis Method Using Benzoic Acid Derivatives as Starting Materials **
    Using benzoic acid as starting materials, the mixed acid of concentrated sulfuric acid and concentrated nitric acid is first used for nitration reaction, and a nitro group is introduced into the benzoic acid benzene ring to generate 3-nitrobenzoic acid. After that, through a reduction reaction, such as iron powder and hydrochloric acid as reducing agents, the nitro group is reduced to an amino group to obtain 3-aminobenzoic acid. Next, the diazotization-bromination reaction is used to convert the amino group into a bromine atom to generate 3-bromobenzoic acid. Under suitable reaction conditions, 4-bromo-6-hydroxybenzoic acid is obtained by introducing hydroxyl groups into the benzene ring with specific hydroxylating reagents (such as potassium hydroxide, copper oxide, etc.). Although this method involves many steps, it has a wide range of raw materials, and the reaction conditions and reagents can be flexibly adjusted according to different needs to optimize the synthesis route.
    In which fields is 4-chloro-6-fluoroquinoline used?
    4-Deuterium-6-tritium square light has a wide range of uses. In the field of industrial technology, this light can help refine equipment. With its unique nature, it can be used in subtle places to clearly detect flaws, making equipment more sophisticated, and can be used in etching techniques to form extremely fine lines, which is of great benefit to micro-electric parts.
    In the world of medicine, it also has its power. 4-Deuterium-6-tritium square light can be used as a diagnostic aid, through the body, showing the shape of the viscera, helping doctors to identify diseases. It can also be used as a healing method, using its light and heat to treat certain injuries, promote the recovery of cells, and heal wounds.
    In the realm of scientific research, this light is a powerful tool. It can explore the microstructure of matter and study the rules of its sexual change. In the study of chemistry, it can investigate the movement of molecules, the mechanism of response, the way of reaction, and the system of new things. In the study of physics, it can explore the wonders of the microscopic, help solve the secrets of the quantum, and understand the transfer of energy.
    In the industry of agriculture and mulberry, 4-deuterium-6-tritium square light can also increase color. It can help plant cultivation, adjust its photosynthesis, promote its growth, increase its yield, and kill pests, protect the safety of crops, reduce the application of medicine, and protect the fertilizer of soil.
    Overall, 4-deuterium-6-tritium square light has extraordinary uses in the fields of industry, medicine, research, and agriculture, contributing a lot to the prosperity of the world.
    What is the market outlook for 4-chloro-6-fluoroquinoline?
    Today, the world is on the rise, and the market is bustling. The 4-deuterium-6-tritium square light has a promising future in the city. Looking at all kinds of things, science and technology are flourishing. This 4-deuterium-6-tritium square light is also expected to show extraordinary capabilities by taking advantage of the east wind of the times.
    Fu 4-deuterium-6-tritium square light has unique properties and has the quality of being different from ordinary things. In the field of industry, it can be used as an efficient energy source to assist the operation of equipment and improve the efficiency of production. Nowadays, in the period of energy revolution, traditional energy sources are gradually frowning, and clean energy is the most important in the world. If 4-deuterium-6-tritium square light can be used well, with its high efficiency and cleanliness, it will definitely add strong impetus to industry and become the foundation for industrial innovation.
    As for people's livelihood, 4-deuterium-6-tritium square light can also be used. Home lighting, if used as a source, can make the room bright and soft, and the energy consumption is low, which can save tariffs for the people; in the country, it can reduce energy consumption. Furthermore, in the realm of transportation, with 4-deuterium-6-tritium square light as the driving force, the vehicle is feasible for a long time and fast, the exhaust gas is less discharged, the environment is protected, and the convenience of travel and the goodness of the ecology can be obtained at the same time.
    And on the road of business, 4-deuterium-6-tritium square light also contains business opportunities. When new things appear, everyone will pay attention to them. If they can be extended, setting up factories and selling their products will lead to competition among merchants, and the accumulation of funds will become a prosperous city. The development of this product requires the joint efforts of all talents, so that the academic style can be revived, professional people can be cultivated, and talents can be stored for the long-term development of the industry.
    However, there are also difficulties in entering the market. The intensive research of technology takes time, and the control of costs is not easy. But with time, with the wisdom of everyone, the difficulties of technology can be overcome, and the high barrier of cost can be reduced. 4-deuterium-6-tritium square light will surely be able to become popular in the market, benefit the people of the world, and become another scene of prosperity in the prosperous world.