Quinoline 4 Bromo 8 Methoxy
quinoline thiophene imidazole thiazole

quinoline, 4-bromo-8-methoxy-

Taiy Chemical

    Specifications

    HS Code

    474221

    Chemical Formula C10H8BrNO
    Molar Mass 238.08 g/mol
    Appearance Solid (predicted, actual may vary)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, sensitive to light and air over long - term

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    General Information
    Where to Buy quinoline, 4-bromo-8-methoxy- in China?
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    Frequently Asked Questions

    As a leading quinoline, 4-bromo-8-methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-bromo-8-methoxyquinoline?
    4-Bromo-8-methoxybenzaldehyde is an organic compound with unique chemical properties. In this substance, both bromine atoms and methoxy groups have a significant impact on the chemical properties of benzaldehyde.
    Bromine atoms have strong electronegativity, which can change the density of electron clouds in the benzene ring. In electrophilic substitution reactions, bromine atoms are ortho and para-sites, which makes the reaction easier to occur in their ortho and para-sites. For example, during nitration reactions, nitro groups tend to enter the ortho and para-sites of bromine atoms. In addition, bromine atoms can participate in substitution reactions, such as with nucleophiles, and bromine atoms can be replaced to form new organic compounds. < Br >
    Methoxy belongs to the power supply group, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution. Its localization effect on benzaldehyde is ortho-and para-position, and there is a superposition with the localization effect of bromine atoms. In some reactions, the power supply action of methoxy group will change the electron cloud distribution on the benzene ring, thereby affecting the reactivity and selectivity.
    And aldehyde group is a key functional group of 4-bromo-8-methoxybenzaldehyde, and its chemical properties are active. The aldehyde group can undergo oxidation reactions, such as being oxidized to a carboxyl group under the action of mild oxidizing agents; it can also undergo condensation reactions with compounds with active hydrogen, such as acetalylation with alcohols in the presence of acidic catalysts, to generate acetals. At the same time, the aldehyde group can also participate in the reduction reaction, such as reducing it to alcohol hydroxyl groups with suitable reducing agents.
    4-Bromo-8-methoxybenzaldehyde has various chemical properties due to the interaction of different functional groups it contains. It has important uses in the field of organic synthesis and can be used to prepare a variety of organic compounds with special structures and functions.
    What are the physical properties of 4-bromo-8-methoxyquinoline?
    4-Hydroxy-8-methoxybenzaldehyde, its physical properties are as follows:
    This substance is mostly crystalline solid at room temperature. When it is pure, it is white in color and radiant in appearance, like frost and snow. Its crystalline morphology is regular, and fine crystal structures can be seen under light, shining brightly.
    The melting point is quite fixed, about a specific temperature range. This property makes it crucial for the identification and purification of substances. If you want to know its purity, you can observe the deviation between its melting point and the standard melting point. The smaller the deviation, the higher the purity.
    Its boiling point also has a specific value. When heated to the corresponding temperature, it changes from liquid to gas. This property has a wide range of uses in separation, purification and chemical production processes. It can be separated from other substances by distillation according to its boiling point difference to achieve the purpose of purification.
    4-hydroxy- 8-methoxybenzaldehyde is slightly soluble in water, just like the difficulty of oil and water. However, in organic solvents, such as ethanol, ether, etc., the solubility is quite good. This property is convenient for the preparation, extraction and reaction process, the selection of suitable solvents, so that the reaction can be carried out more easily, and it is also conducive to the separation and purification of the product.
    Its unique smell has a light and elegant fragrance, not a strong pungent smell, but like a faint flower fragrance, lingering in the nose, giving people a fresh feeling. This odor property may play a unique role in the field of fragrance blending and other fields, providing the possibility for blending a unique aroma.
    Its density, compared with common organic compounds, has its specific value. This value is of great significance in studying its distribution in solution, phase equilibrium relationship, etc. In some experiments or production scenarios involving mixed solutions, density data can help researchers or producers understand the interaction and distribution of substances, and then optimize the process.
    What is the common synthesis method of 4-bromo-8-methoxyquinoline?
    The common synthesis method of 4-hydroxyl-8-methoxybenzaldehyde is based on various organic reactions, and it is achieved by different raw materials and steps.
    First, it can be started by phenols with corresponding substituents. First, phenol is used as a raw material, and methoxy is introduced through methoxylation. Methoxylation is often reacted with halogenated methane (such as iodomethane) and base (such as potassium carbonate) in a suitable solvent (such as N, N-dimethylformamide). The oxygen anion of phenolic hydroxyl attacks the carbon atom of halogenated methane to form a methoxy substitution product. Then, the hydroxymethyl group is introduced into the para-position of the phenol, which can be reacted with formaldehyde or paraformaldehyde as the hydroxymethyl source, catalyzed by Lewis acid (such as aluminum trichloride), and reacted in a suitable organic solvent (such as dichloromethane). The obtained intermediate containing hydroxymethyl group is then mildly oxidized, such as manganese dioxide or Dess-Martin oxidant, which can oxidize the hydroxymethyl group to an aldehyde group to obtain 4-hydroxy- 8-methoxybenzaldehyde.
    Second, benzaldehyde with appropriate substitution mode can also be started. First, the benzaldehyde ring of benzaldehyde is modified, and the methoxy group and hydroxyl group are introduced at specific positions by electrophilic substitution reaction. In the electrophilic substitution reaction, according to the electron cloud distribution and localization effect of the benzene ring, suitable electrophilic reagents (such as halogenated methoxylation reagents, hydroxylation reagents) are used to react under acidic or basic catalytic conditions. If there are both aldehyde groups on the benzene ring and aldehyde groups are used as meta-localizers, protection and de-protection strategies can be used to protect the aldehyde groups first, such as to form acetals, then perform benzene ring substitution reaction, and then deprotect and restore the aldehyde groups to obtain the target product.
    Third, organic metal reagents can be used to participate in the reaction synthesis. Halogenated aromatics are used as raw materials to react with magnesium powder to form Grignard reagents, and then react with carbonyl compounds containing methoxy groups and aldehyde groups. The carbon anion of Grignard's reagent is nucleophilic addition to the carbonyl group. After hydrolysis, the carbon skeleton of the target product is constructed. After the product is properly functionally transformed to achieve the structure of 4-hydroxyl-8-methoxybenzaldehyde.
    Synthesis methods have their own advantages and disadvantages, and the synthesis path should be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, the yield and purity requirements.
    In which fields is 4-bromo-8-methoxyquinoline used?
    4-N-8-methoxybenzoic acid light has its applications in a wide range of domains. In this field, this light may be able to synthesize certain compounds due to its special actinic properties. For example, in the research and synthesis of specific anti-tumor compounds, its optical properties can be used to promote the specific oxidation of certain molecules to obtain the desired active ingredient of the compound, and the reaction of this light may be able to improve the reaction properties, reduce the number of side effects, and improve the performance of the compound.
    In the field of materials, it also has extraordinary performance. For example, in the field of photochromic materials, 4-N-8-methoxybenzoic acid light can be used as a photosensitive component. When the material is exposed to a specific wave of light, the molecules of the material are subjected to light and changed, resulting in reversible color transformation of the material. This photochromic material can be used as a smart window film to change the light transmittance under different illumination degrees, so as to achieve the purpose of low energy.
    Furthermore, in the field of chemical analysis, 4-8-methoxybenzoic acid light can be used as an important component of optical detection. Based on its photophysical properties and specific analyte-specific interaction, its optical signal such as photometry and waveform can be generated, which can be used to improve the high sensitivity and high sensitivity of the analyte. It plays an important role in environmental pollutant analysis, biomolecular analysis, etc.
    What is the market outlook for 4-bromo-8-methoxyquinoline?
    Today, the world is on the rise, and commerce is flourishing. 4-hydroxy- 8-methoxybenzaldehyde is in the market, and the prospect is quite promising.
    This compound has a wide range of uses. In the field of medicine, it can be a raw material for the synthesis of many drugs. At present, diseases are diverse, and the demand for medicine is increasing, so the research and development of new drugs has not dared to stop for a while. The characteristics of 4-hydroxy- 8-methoxybenzaldehyde can help make a variety of specific drugs and heal patients. With the rise of the pharmaceutical industry, its demand is also increasing.
    And it is in the fragrance industry, it also has unique uses. It can give flavors a different flavor and increase their level and uniqueness. In today's world, people pursue higher quality of life, and the use of fragrances is widely involved in daily use, beauty and other fields. It is the market that has no choice but to demand special fragrance raw materials. 4-Hydroxy-8-methoxybenzaldehyde can occupy a place because of its characteristics.
    Furthermore, in chemical synthesis, it is an important intermediate. The categories of chemical products are complex and changing with each passing day, and the demand for various intermediates continues. 4-Hydroxy-8-methoxybenzaldehyde can participate in many synthesis reactions due to its chemical properties, providing the possibility for the creation of new chemical products. The chemical industry is large in scale and developing rapidly, and there are many opportunities for this compound.
    However, its market is not without challenges. The refinement of the synthesis process and the control of cost are all key. If we can make breakthroughs in the process, reduce its cost, and improve its purity and output, we will be able to stand out in the market competition. And with the stricter environmental regulations, the greening of the production process is also a priority. Only by making the process meet the needs of environmental protection can we develop sustainably.
    In general, 4-hydroxy- 8-methoxybenzaldehyde coexists in today's market with opportunities and challenges. With its wide range of uses and rising demand, with time and proper management, it will be able to bloom in the fields of medicine, flavors, and chemicals, and gain considerable profits. It will sail in the sea of commerce.