Quinoline 3 Carboxy 4 Hydroxy 7 Chloro
quinoline thiophene imidazole thiazole

Quinoline, 3-carboxy-4-hydroxy-7-chloro-

Taiy Chemical

    Specifications

    HS Code

    596030

    Name Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro -
    Chemical Formula C10H6ClNO3
    Molecular Weight 223.61 g/mol
    Appearance Solid (predicted, based on similar compounds)
    Physical State At Room Temp Solid
    Solubility In Water Low (due to non - polar aromatic part, but polar groups may increase slightly)
    Solubility In Organic Solvents Moderate to high in polar organic solvents like DMSO, DMF
    Pka Carboxy Group Around 3 - 5 (estimated for carboxyl group)
    Pka Hydroxy Group Around 9 - 11 (estimated for phenolic - like hydroxy group)
    Uv Visible Absorption Absorption bands in UV region due to aromatic chromophore
    Ir Absorption Characteristic peaks for carboxyl (around 1700 cm⁻¹), hydroxy (around 3200 - 3600 cm⁻¹), and aromatic C - H and C = C (various peaks in 1400 - 1600 cm⁻¹ and 3000 - 3100 cm⁻¹)

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    Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro - what are the chemical properties
    Quinoline-3-carboxyl-4-hydroxy-7-chlorine is a substance with unique and wonderful properties. Its color may be light, and its quality is often in the shape of crystallization, which is slightly glowing under light.
    On the point of melting and boiling, the melting point is fixed, and it varies according to the situation, but mostly in a suitable temperature range. Its boiling point also follows its nature, and it changes when heated. When it reaches a certain degree of heat, it begins to melt into gas and rise.
    In solubility, it varies in various solvents. The solubility of water is minimal, and the properties of water are different from each other, and it is difficult to form a state of dissolution. However, in organic solvents, such as alcohols and ethers, the affinity is added, and it can gradually blend into a uniform liquid.
    Its chemical activity, due to the wonderful structure, carboxyl, hydroxyl and chlorine atoms show their respective abilities. The carboxyl group has the property of acid, and can be combined with bases to form a salt. The hydroxyl group is also not weak, and can be involved in the transformation of esterification, dancing with acids to form esters and leaving fragrance. The side of the chlorine atom can attract the attack of nucleophilic, making the structure variable and producing different derivatives.
    And the ring of quinoline endows it with aromatic properties, with the stability of conjugation, and can resist general chemical changes. However, in case of strong agents, such as strong acids and strong oxidizing agents, it can also be modified, and the bonds between the rings may crack or change, and new substances may be derived, which is all kinds of things.
    This materiality has its uses in the fields of chemical industry and medicine. In chemical industry, it can be used as a raw material to induce changes and make new materials. In medicine, with its activity, it can be used to develop preparations to help remove diseases and diseases. It is really a treasure of chemistry, and it is widely used when the wise are deeply explored.
    Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro - what are the uses
    3-Carboxyl-4-hydroxy-7-chloroquinoline has a wide range of uses. In the field of medicine, it can be used as a key raw material for the creation of antimalarial drugs. Covering malaria is a dangerous disease that seriously endangers the health of the people. The properties of this compound may effectively interfere with the metabolism and reproduction process of malaria parasites, thus achieving the purpose of combating malaria.
    In pesticides, it also has its uses. With its unique chemical structure, new insecticides or fungicides can be developed. In today's agriculture, the ravaging of pests and diseases often leads to reduced crop production. This compound may have inhibitory or killing effects on specific pests or pathogens, help agriculture harvest and ensure food supply.
    In the field of materials science, it also shows potential value. It can be used as a basic material for the synthesis of special functional materials. After specific processing, it can endow the materials with excellent properties such as antibacterial and antioxidant properties, and expand the application range of materials, such as food packaging materials, which can prolong the shelf life of food; used in building materials, which can enhance their durability.
    In the field of chemical research, 3-carboxyl-4-hydroxy-7-chloroquinoline is an important intermediate in organic synthesis. Chemists can use various chemical reactions to derive compounds with more complex structures and unique functions, promoting the development of organic chemistry and opening up paths for the creation and performance exploration of new substances. Overall, this compound holds important application potential in many fields, making it a chemical substance that cannot be ignored.
    Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro - what is the synthesis method
    The synthesis of quinoline-3-carboxyl-4-hydroxy-7-chlorine is a complex and delicate chemical process. Looking at the work of Tiangong Kaiwu, although the synthesis of this specific compound is not directly described, the chemical process wisdom contained in it can be used for reference.
    To synthesize this compound, the first thing to do is to clarify its molecular structure and chemical properties. The quinoline ring is its main structure, and the 3-carboxyl group, the 4-hydroxyl group and the 7-chlorine atom each have their own unique chemical activities. At the beginning of synthesis, appropriate starting materials should be selected. Or the compound with the basic structure of quinoline can be selected as the group, and then the desired functional group can be gradually modified.
    If a simple quinoline derivative is used as the starting material, under specific reaction conditions, a suitable electrophilic reagent is introduced into the 7-position chlorine atom. This step requires fine regulation of the reaction temperature, time and reagent dosage to precisely locate the chlorine atom and prevent other check point side reactions. After the chlorine atom is in place, when the carboxyl group and hydroxyl group are introduced, the carboxyl group can be formed at the 3-position by a specific oxidation reaction. This process requires finding a suitable oxidizing agent and controlling the degree of reaction to prevent excessive oxidation from destroying the product.
    As for the introduction of the 4-position hydroxyl group, it can be achieved by reactions such as nucleophilic substitution. The choice of solvent and the addition of catalyst are all crucial. The solvent needs to be able to dissolve the reactants and promote the reaction process; the catalyst can speed up the reaction and improve the yield. After each step of the reaction, the pure product should be removed by appropriate separation and purification methods, such as distillation, recrystallization, column chromatography, etc., to prepare high-quality raw materials for the next reaction. In this way, step by step, according to a reasonable reaction route and precise experimental operation, it is expected to obtain the product of quinoline-3-carboxyl-4-hydroxy-7-chloride.
    Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro - in what areas
    Quinoline-3-carboxyl-4-hydroxy-7-chlorine is used in many fields. In the field of medicine, it can be used as a key intermediate in drug synthesis. Due to its specific chemical structure, it has potential biological activity, or can participate in the creation of antibacterial and antiviral drugs. By binding to specific targets of pathogens, it can inhibit or kill pathogens.
    In the field of materials science, it also has its uses. Or can be used to prepare functional materials, such as optical materials. Due to its special structure, or endowing materials with unique optical properties, such as fluorescence properties, it is used in optical sensors or Light Emitting Diodes to improve their performance and function.
    Furthermore, in the field of agriculture, it may be used as a raw material for pesticide synthesis. After rational design and modification, pesticides with high-efficiency control effect on crop pests can be prepared. By virtue of its own chemical activity, it can interfere with the physiological process of pests, ensure the healthy growth of crops, and improve yield and quality.
    In addition, in scientific research and exploration, it is an important object of organic synthetic chemistry research. Chemists can gain in-depth insight into the mechanism of organic reactions by exploring their structural modification and reaction, expand the methodology of organic synthesis, and provide a theoretical and practical basis for the creation of more complex and specific functional compounds.
    Quinoline, 3 - carboxy - 4 - hydroxy - 7 - chloro - what is the market outlook
    Now there are quinoline, its 3-carboxyl-4-hydroxy-7-chlorine variant, which is worthy of careful investigation in the prospect of market conditions.
    Looking at the field of medicine, this compound may have unique effects. Because of its specific chemical structure, it may be compatible with many biological targets in the body. In the way of antibacterial, it may be able to exhibit extraordinary properties, with its structural characteristics, or it may break the defense of bacteria and prevent its growth and reproduction. And in the field of antivirus, it may also be possible, or it can use its structure to interfere with the process of virus invasion into host cells, thus opening up a new path for antiviral drug research.
    Furthermore, in the field of materials science, it also has potential opportunities. Due to its special functional groups, it may be used to prepare new functional materials. For example, in optoelectronic materials, the optical and electrical properties of the material can be optimized by virtue of its electronic structure characteristics, so that the material can perform better in Light Emitting Diode, solar cells and other devices, and then promote the development of related industries.
    However, its market prospects are not entirely smooth. The process of synthesizing this compound may be complex, and cost control is also a major challenge. If an efficient and economical method cannot be found, large-scale production and application may be hindered. And market competition should not be underestimated. Compounds of the same kind or with similar functions can gain a place in the market. Only by continuously improving technology and improving the quality and performance of products can we gain a foothold in the market.
    In summary, the 3-carboxyl-4-hydroxy-7-chlorine variant of quinoline, although it has unlimited opportunities in the fields of medicine and materials science, still needs to overcome many difficulties such as synthesis process and market competition.