Name | oxyquinoline |
Chemical Formula | C9H7NO |
Molar Mass | 145.16 g/mol |
Appearance | Yellowish - brown crystals or powder |
Odor | Characteristic odor |
Melting Point | 76 - 77 °C |
Boiling Point | 267 - 269 °C |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in ethanol, ether, chloroform |
Ph | Neutral |
Stability | Stable under normal conditions |
Flash Point | 144 °C |
What are the main uses of oxyquinoline?
Oxyquinoline has a wide range of uses. One of them is in the field of medicine, with antibacterial and antifungal properties. It can be made into an external ointment, applied to the skin, to treat skin diseases, such as ringworm scabies, with its antibacterial power, inhibit the reproduction of pathogens, and promote skin rehabilitation. It can also be used for the treatment of eye diseases, reduce eye inflammation, and protect the health of the eyes.
Second, in the chemical industry, it is an important chelating agent. It can complex with many metal ions to form a stable complex. For the separation and purification of metal ions, the effect is significant. For example, in ore smelting, it helps to separate specific metal ions from complex ore components, improving the purity and efficiency of metal extraction.
The third is analytical chemistry, which is a commonly used analytical reagent. It is used to detect and determine specific metal ions, and to sensitively detect the existence and content of metal ions by means of the color change or other physical and chemical properties of their complexation with metal ions. For example, in water quality testing, some trace metal ions in water can be measured to judge the quality of water.
The fourth is in materials science, and it is also used. Specific materials can be added to improve material properties. For example, adding oxyquinoline to some polymer materials enhances the anti-oxidation and anti-corrosion properties of materials, prolonging the service life of materials, and is widely used in construction, machinery and other fields.
What are the chemical properties of oxyquinoline?
Oxyquinoline is also an organic compound. It is weakly basic and can form salts with acids. Because it contains nitrogen atoms, nitrogen has lone pairs of electrons, so this property is apparent, which is one of its important chemical properties.
Oxyquinoline also has coordination properties. Its nitrogen atoms and hydroxyl oxygen atoms can provide electron pairs and can complex with metal ions. In case of certain metal ions, it can form stable complexes. This property is quite useful in analytical chemistry and other fields, or can be used to separate and identify metal ions.
Furthermore, oxyquinoline has certain redox properties. Under certain conditions, some groups in its structure can be oxidized or reduced. Oxidation reactions are more likely to occur at the hydroxyl group. Under the action of appropriate oxidants, the hydroxyl group may be transformed into other oxygen-containing functional groups. In the presence of strong reducing agents, unsaturated bonds in the molecule may also be reduced.
Its benzene ring part can undergo electrophilic substitution reaction. Because the benzene ring has electron cloud density, it can attract electrophilic reagents to attack. If under appropriate catalysts and conditions, halogenation, nitrification, sulfonation and other electrophilic substitution reactions can occur, and corresponding substituents are introduced at specific positions in the benzene ring, thereby deriving a variety of derivatives and expanding their application scope. In short, oxyquinoline is rich in chemical properties and has important uses in many fields.
What are the precautions for oxyquinoline during use?
For those who use oxyquinoline, when using it, all kinds of things to pay attention to must not be ignored.
The first priority is safety. Its sex may be toxic, and it can be harmful if it touches the body, inhales it, or eats it. During operation, protective equipment must be worn, such as gloves, masks, and eyepieces, to prevent it from touching the body and avoiding it from entering the body. And it is in a well-ventilated place, so that harmful gas can dissipate quickly, so as not to accumulate in the room and endanger the human body.
In addition, when oxyquinoline encounters fire or ignition, it must be stored and used away from fire and heat sources, and avoid high temperatures. The warehouse should be cool, dry, and ventilated, and fireworks should be prohibited. Fire prevention should not occur. < Br >
It is also chemically active, or reacts with other things. Before use, it must be carefully studied to prevent dangerous changes caused by improper mixing, such as explosions, toxins, etc. When mixing, it is advisable to follow the procedures, do it slowly, and closely observe its changes.
When weighing and dosing, accuracy is crucial. Less will not achieve the expected effect, and more may cause adverse reactions. Therefore, the meter must be accurately calibrated, and the operation must be careful and fine, so that the dose is correct.
After use, the treatment should not be ignored. Residues should not be discarded at will, and must be properly disposed of in accordance with environmental protection regulations, so as not to pollute the environment. The utensils used should also be cleaned for later use.
In short, with oxyquinoline, safety is the top priority, and all things are done with caution and in accordance with regulations, in order to avoid disasters and seek safety and achieve the purpose of its use.
What is the market price of oxyquinoline?
I look at you and ask what the market price of oxyquinoline is. However, the market is impermanent, and its price varies from time to time, from quality to quality, and also varies according to changes in supply and demand.
In the past, oxyquinoline was in the market, and the price was tens of gold per kilogram. If its quality is pure, the workmanship is good, and the price is higher. However, the market circulates, and the production and supply increase, the price may drop; if raw materials are scarce, it is difficult to make, and there are many people who need it, the price may rise.
Today, if you want to confirm the price, you can only get its price in the near future when you visit the cities and ask the merchants who work in this industry, or look at the net of trade. According to common sense, the price per kilogram may be around a hundred gold, but this is only speculation and cannot be confirmed. The change of the market is also fast, and the movement of the price is also fast, so it must be based on real-time feelings to know the exact price.
How is oxyquinoline produced?
Oxyquinoline is also an organic compound. Although the method of its preparation is not detailed in ancient books, the current process has about the following numbers.
The first is the Scroop synthesis method. Co-heating with o-aminophenol, glycerol, concentrated sulfuric acid and weak oxidants (such as nitrobenzene). Under the action of concentrated sulfuric acid, glycerol is dehydrated to acronaldehyde. Acronaldehyde and o-aminophenol are nucleophilically added to form cyclized products, and then oxidized by weak oxidants to obtain oxyquinoline. This process requires temperature control, quantity control, and strict inspection of the reaction state. If the temperature is too high, or the side reaction is produced, the product is impure.
The second is the Pomerantz-Fritsch reaction. Using o-aminobenzaldehyde and acetone, condensation under acid catalysis, and then cyclization and oxidation to form oxyquinoline. Among them, the choice and dosage of acid are related to the reaction rate and yield, and the cyclization and oxidation steps must also be carried out, otherwise it will be difficult to achieve the best effect.
Another person uses quinoline as a raw material to obtain oxyquinoline through substitution reaction. Select an appropriate reagent, and under specific conditions, make the quinoline at a specific position replaced by a hydroxyl group. This requires fine study of the reaction conditions to ensure that the substitution check point is accurate and the product is pure.
When preparing, the purity of the raw material, the purity of the instrument, and the care of the operation are all key. In each step, it is necessary to follow the specifications, observe the phenomenon in detail, and fine-tune the parameters in order to obtain high-quality oxyquinoline.