O Toluquinoline
Quinoline Thiophene Imidazole Thiazole
o-toluquinoline
Name o - toluquinoline
Chemical Formula C10H9N
Molar Mass 143.19 g/mol
Appearance Solid
Color Yellow - brown
Odor Characteristic
Melting Point 32 - 34 °C
Boiling Point 264 - 265 °C
Density 1.052 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
FAQ

What are the main uses of o-toluquinoline?

O-toluquinoline (o-toluquinoline) has a wide range of uses. In the field of chemical industry, it is often used as a raw material for organic synthesis. Because of its special chemical structure, it can be prepared by a variety of chemical reactions, such as dyes, pharmaceutical intermediates, etc. In the preparation of dyes, it can give dyes unique color and properties, making it excellent in dyeing processes.

In the pharmaceutical chemical industry, o-toluquinoline can be used as a key intermediate to help synthesize drug molecules with specific pharmacological activities. By modifying and modifying its structure, drugs for various diseases can be developed, opening up new avenues for pharmaceutical research and development.

In addition, in the field of materials science, it also has applications. It can be combined with other materials through specific treatment to improve the properties of materials, such as enhancing the stability of materials and improving their optical properties. In short, o-toluenylquinoline plays an important role in the chemical industry, medicine, materials and other fields, and has a profound impact on the development of various industries.

What are the physical properties of o-toluquinoline?

O-toluquinoline (o-toluquinoline) is one of the organic compounds. Its physical properties are quite unique, and are described as follows:

Looking at its morphology, under normal temperature and pressure, it often takes the shape of a solid state, with a color or light yellow, or nearly colorless, with a certain crystalline state. This is also a sign of its appearance.

When it comes to the melting point, it is about [X] ° C. The value of the melting point is an inherent property of the substance, and it is a key parameter when identifying and purifying this substance. Due to the specific intermolecular forces, the melting point is in this range, which is also closely related to the structure of the molecule.

In terms of boiling point, it is roughly [X] ° C. The boiling point is the temperature limit at which a substance changes from a liquid state to a gaseous state. The boiling point of o-toluenylquinoline reflects the energy required for its molecules to break free from the liquid phase, and this energy requirement is closely related to the interaction between molecules.

In terms of solubility, in organic solvents, such as ethanol, ether, etc., there is a certain solubility. This is because its molecular structure contains groups that can form interactions such as van der Waals force and hydrogen bonds with organic solvent molecules, so it is soluble. However, in water, its solubility is poor, because the force between water molecules and o-toluenylquinoline molecules is weak, and the polarity difference between the two is large.

As for the density, it is about [X] g/cm ³. This value reflects the mass of the substance per unit volume and is related to the accumulation mode and relative molecular weight of the molecule. The characteristics of density are reflected in the process of separation and mixing of substances.

In addition, o-toluenylquinoline has a certain degree of volatility. Although the degree of volatilization is limited, under specific conditions, it cannot be ignored. Its volatilization rate is related to factors such as temperature, surface area, and air circulation.

All these physical properties are important properties of o-toluenylquinoline. They are all useful in the fields of organic synthesis and materials science, helping researchers to further explore the properties and applications of this substance.

Is the chemical properties of o-toluquinoline stable?

O-toluquinoline is one of the most important compounds. Its chemical properties, in terms of qualitative, are not good. The reason is that the molecule contains quinoline, which has the characteristics of aromatics, and is formed by the fusing of benzene and pyridine. The distribution of aromatics is highly distributed in a wide range, forming a common system of determinations. This is the foundation of the determinations of o-toluquinoline.

Furthermore, the methyl groups in the molecule of o-toluquinoline can be inverted, but the qualitative effects of the whole molecule are still controllable. The effect of methyl supplementation can change the density of children on quinoline, but the co-action of quinoline does not break the stable system.

Under normal conditions, o-toluquinoline can resist many normal chemical reactions. It can withstand a certain degree of acid environment, and under neutral and weak acidic and weak conditions, the molecule can be formed and transformed. Even if it encounters oxidation or original conditions, specific reaction components are required to promote its biochemical reaction, which is sufficient to determine its chemical resistance.

What are the preparation methods of o-toluquinoline?

There are several ways to prepare o-toluquinoline.

First, o-toluquinoline and o-chlorobenzaldehyde are used as raw materials. The two can be obtained by condensation reaction in an appropriate solvent and under the action of a catalyst. First, o-toluquinoline and o-chlorobenzaldehyde are placed in a reaction kettle in a certain proportion, an appropriate amount of solvent such as ethanol is added, and then a little catalyst such as acid is added. It is heated to a suitable temperature, usually between tens and hundreds of degrees Celsius. When the reaction is completed, o-toluquinoline can be obtained through separation and purification. The principle of this reaction is based on the condensation of amine and aldehyde groups to form the basic structure of quinoline. < Br >
The second is to use o-toluic acid and aniline as starting materials. The o-toluic acid is first converted into its acyl chloride form, which is often treated with sulfoxide chloride and other reagents. After obtaining o-toluyl chloride, it reacts with aniline under the catalysis of a base. The base can be selected from pyridine, etc., and the reaction is carried out in an organic solvent such as dichloromethane. The intermediate product is formed by acylation reaction, and then under appropriate conditions, such as heating and under the action of a dehydrating agent, the cyclization forms o-toluenylquinoline. This process involves acylation, cyclization and other steps to gradually construct the structure of the target product.

The third is a variant of the Fisher indole synthesis method. The reaction of o-toluene hydrazine with the corresponding ketone first forms hydrazone, and then under acid catalysis, through a series of processes such as rearrangement and cyclization, o-toluene quinoline can be prepared. In the specific operation, o-toluene hydrazine is mixed with suitable ketones in an acidic solution, such as hydrochloric acid solution, and the temperature and reaction time are controlled to make the reaction proceed in an orderly manner, and then the product is obtained by separation and purification. This method uses the special reaction of phenyl hydrazine and ketone to ingeniously construct the structure of quinoline derivatives. The above methods have their own advantages and disadvantages. In practical application, according to the availability of raw materials, cost, yield and other factors, the appropriate method should be selected to prepare o-toluene quinoline.

What is the price range of o-toluquinoline in the market?

I have not heard the exact price of o-toluquinoline in the market. However, if you want to know the price of this product, you can explore it in various ways. First, in the specialized market for trading chemical raw materials, if you consult the merchants, you must get the current price. Second, look online. There are many websites for selling chemical products. Log in to check carefully, or you can know the price range. Third, interview experts and merchants in the chemical industry. With their experience, you can also get clues about the price.

The price of the cover is not constant, and it often changes due to the abundance of raw materials, difficulties in process, and changes in market supply and demand. If the raw materials are abundant, the process is simple, and the market demand is low, the price may be lower; if the raw materials are scarce, the preparation is difficult, and the market is seeking, the price will be higher.

Although I cannot directly tell the price range of o-toluquinoline in the market, according to the above methods, if you search carefully, you will be able to obtain its approximate price. I hope you can get the required information smoothly.