N 1 3 Benzodioxol 5 Yl 2 Methylquinoline 8 Sulfonamide
quinoline thiophene imidazole thiazole

N-(1,3-benzodioxol-5-yl)-2-methylquinoline-8-sulfonamide

Taiy Chemical

    Specifications

    HS Code

    258850

    Chemical Formula C18H14N2O4S
    Molar Mass 354.38 g/mol
    Appearance Solid (predicted)
    Solubility In Water Low (predicted due to non - polar aromatic rings)
    Logp Predicted to be relatively high (hydrophobic due to aromatic rings)
    Vapor Pressure Very low (predicted for a solid organic compound)

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    General Information
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    Frequently Asked Questions

    As a leading N-(1,3-benzodioxol-5-yl)-2-methylquinoline-8-sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of N- (1,3-benzodioxane-5-yl) -2-methylquinoline-8-sulfonamide?
    This is a structural problem of organic compounds. To know the chemical structure of N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -2-methylbenzyl-8-quinoline carboxamide, it is necessary to analyze the composition and connection of each part in detail.
    "1,3-naphthaleno-dioxacyclopentene-5-yl", naphthalene is a fused aromatic hydrocarbon composed of two benzene rings sharing two adjacent carbon atoms. 1,3-Naphthaleno-dioxacyclopentene is located at a specific position (1,3 position) of the naphthalene ring and has the structure of dioxacyclopentene. The dioxacyclopentene is a five-membered ring structure containing two oxygen atoms, and the 5-group indicates that the substituent is attached to the 5-position of the parallel ring structure.
    "2-methylbenzyl", benzyl is benzyl, that is, benzene ring-linked methylene (-CH ² -), and 2-methyl indicates that the ortho-position (2 position) of the carbon atom connected to the methylene on the benzene ring has methyl (-CH ²) substitution.
    "8-quinoline carboxylamide", quinoline is a nitrogen-containing heterocyclic compound, which is fused from a benzene ring and a pyridine ring. 8-quinoline carboxylamide, or carboxylamide group (-CONH -), is connected to the 8th position of the quinoline ring.
    In summary, the structure of this compound is as follows: naphthalene-dioxane is used as a structural unit, and its 5th position is connected to methylene (-CH -2 -), and this methylene is then connected to the 2-methyl benzyl moiety; at the same time, the carboxamide group at the 8th position of the quinoline ring is connected to the above structure through appropriate chemical bonds to form N- (1,3-naphthalene-dioxane-5-yl) -2-methylbenzyl-8-quinoline carboxylamide. In this way, the chemical structure of this complex organic compound can be clearly understood.
    What is the main use of N- (1,3-benzodioxane-5-yl) -2-methylquinoline-8-sulfonamide?
    The main use of N- (1,3-naphthalenedioxycyclopentene-5-yl) -2-methylbenzoyl-8-quinoline is that it plays a key role in the field of medicinal chemistry and organic synthesis.
    In the field of pharmaceutical chemistry, it exhibits potential biological activities. Many compounds containing quinoline and naphthalenedioxycyclopentene structures have been confirmed to have significant pharmacological properties. For example, quinoline compounds often exhibit antibacterial, anti-inflammatory and anti-tumor activities. The structure of naphthalenedioxycyclopentene may optimize the lipophilicity and spatial structure of the compounds and enhance their interaction with biological targets. Therefore, N- (1,3-naphthalene dioxacyclopentene-5-yl) -2-methylbenzoyl-8-quinoline is very likely to be modified and optimized to develop into a new type of drug for the treatment and prevention of diseases.
    In the field of organic synthesis, this compound plays a crucial role as an important intermediate. Its complex and unique structure provides a basis for the construction of more complex organic molecules. Through organic synthesis methods, various functional reactions can be carried out on it, and different substituents can be introduced to expand the structural diversity of the compound, and a series of organic materials with special properties and uses can be synthesized, such as organic luminescent materials for optoelectronics, nonlinear optical materials, etc.
    In addition, in materials science research, it may contribute to the development of new functional materials. With in-depth investigation of the relationship between its structure and properties, materials with unique physical and chemical properties may be developed to meet the needs of different fields. In short, N- (1,3-naphthalenedioxane-5-yl) -2-methylbenzoyl-8-quinoline has a unique structure and has broad application prospects and research value in many fields.
    What are the synthesis methods of N- (1,3-benzodioxane-5-yl) -2-methylquinoline-8-sulfonamide
    To prepare N- (1,3-naphthalene dioxacyclopentene-5-yl) -2-methylbenzylamine-8-quinoline, the method is as follows:
    First take 1,3-naphthalene dioxacyclopentene-5-aldehyde, and carry out condensation reaction with 2-methylbenzylamine with appropriate organic reagents and conditions. During this condensation process, attention should be paid to the temperature of the reaction and the choice of solvent. Commonly used solvents, such as ethanol, dichloromethane, etc., can be selected according to the characteristics of the reaction. Temperature control is also critical. Generally, under moderate heating, the two can fully react to form an imine intermediate.
    Then, the imine intermediate is reduced. The method of reduction can be catalyzed by hydrogenation, using palladium carbon as a catalyst and reacting in a hydrogen environment. This process requires attention to the pressure of hydrogen and the amount of catalyst. If the conditions are suitable, the imine can be smoothly converted into the target product N- (1,3-naphthalene dioxacyclopentene-5-yl) -2-methylbenzylamine.
    As for the combination with 8-quinoline, the appropriate functional group activation of 8-quinoline can be carried out first. For example, if there is a halogenated check point on 8-quinoline, a halogen atom can be introduced through a halogenation reaction. Then, the activated 8-quinoline and the prepared N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -2-methylbenzylamine are coupled in the presence of bases and suitable ligands. The choice of bases, such as potassium carbonate, sodium carbonate, etc.; the ligand can be selected from suitable phosphine ligands, etc. Through this coupling reaction, the purpose of generating N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -2-methylbenzylamine-8-quinoline can be achieved. After the reaction is completed, the pure product can be obtained through separation and purification steps, such as column chromatography, recrystallization, etc.
    What is the safety of N- (1,3-benzodioxane-5-yl) -2-methylquinoline-8-sulfonamide?
    The safety of N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -2-methylbenzyl-8-quinoline carboxylic acid is related to many aspects.
    In terms of chemical structure, its unique structural units such as naphthaleno-dioxacyclopentene and quinoline carboxylic acid endow it with specific chemical activities. However, under certain conditions, or due to the characteristics of chemical bond energy and electron cloud distribution, such complex structures have different stability, or chemical reactions occur in specific environments, resulting in unknown products, which threaten safety.
    From the perspective of toxicity, its toxic reaction to organisms must be investigated through rigorous experiments. Some compounds with similar structures may be toxic to biological cells, interfere with the normal metabolism, proliferation and differentiation of cells, and even cause genetic mutations. N- (1,3-naphthalene dioxacyclopentene-5-yl) -2-methylbenzyl-8-quinoline carboxylic acids have different toxic effects on different biological systems, such as mammals, aquatic organisms, etc., and the degree of toxicity may vary depending on factors such as dose, exposure time, and exposure route.
    In terms of environmental impact, if it enters the environment, it will undergo a complex migration and transformation process. Its stability and degradation characteristics in environmental media such as water, soil, and atmosphere are unknown, or it persists in the environment, enriches through the food chain, and affects the balance of the ecosystem. For example, it may affect the structure and function of microbial communities, and then affect the material cycle and energy flow of the entire ecosystem.
    To accurately evaluate its safety, comprehensive toxicological experiments are required, covering studies of acute toxicity, chronic toxicity, genetic toxicity, and reproductive toxicity, as well as in-depth environmental behavior studies, including environmental fate, bioaccumulation, and degradation, in order to obtain reliable data and accurately determine its safety.
    What are the relevant market application cases of N- (1,3-benzodioxane-5-yl) -2-methylquinoline-8-sulfonamide?
    Eh! The relevant market application cases of Fu N- (1,3-naphthalene-heterocyclopentene-dioxide-5-yl) -2-methylbenzyl-8-quinoline are quite rich.
    In the field of Guanfu Medicine, there are those who have developed anti-swelling and ulceration drugs based on these compounds. The unique structure of this compound can interact with specific receptors in swollen cells, inhibit their proliferation and induce apoptosis, so it is important for doctors. In the past, doctors have found that such compounds can effectively inhibit the growth of certain swollen cells in experiments, and have little damage to normal cells. They are like sharp blades, which can accurately remove diseases without harming innocent people. < Br >
    In the genus of materials science, there is also a place for it. With this as a raw material, the optical material obtained has specific optical properties and can be used in optoelectronic devices, such as Light Emitting Diode. It can emit specific light, which makes the light effect and color performance of the device excellent, like a luminous pearl, shining brightly in the realm of optoelectronics.
    And in agricultural plant protection, there are also related explorations. Based on this compound, new pesticides are developed. Because of its unique repellent or killing effect on some pests, and compared with traditional pesticides, it is environmentally friendly and less toxic, just like a guard and a farmer, and protects the ecology.
    It is more in the field of analysis and detection, and uses this as a probe to accurately identify specific substances. After it binds to the target, it shows specific signal changes, which helps researchers in complex systems, such as stripping cocoons, clarifying ingredients, and gaining insight.
    All these examples demonstrate the potential value of N- (1,3-naphthalene and heterocyclopentene dioxide-5-yl) -2-methylbenzyl-8-quinoline in multiple domains, which is a great contribution to the progress of various industries.