Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate

This is the chemical structure of methyl 4- (4 '-fluorophenyl) -2 - (cyclopropyl) -3 -quinoline carboxylic acid ester. Looking at its name, it can be seen that this compound contains a quinoline parent nucleus, with a carboxylic acid methyl ester group at the 3rd position of the quinoline ring, a 4' -fluorophenyl group at the 4th position, and a 2-position catenyl propyl group.
Quinoline is an aromatic compound with an nitrogen heterocycle, which is common in many drugs and bioactive molecules. The 3-position carboxylic acid methyl ester group of this compound can affect molecular polarity and reactivity, and may also play a key role in certain reactions or biological processes, such as participating in ester hydrolysis reactions, or binding with specific receptors by weak interactions such as hydrogen bonds.
4 '-fluorophenyl, fluorine atoms have strong electronegativity, which can affect the distribution of molecular electron clouds by inducing effects, which in turn affect molecular physical and chemical properties, such as solubility and stability. In terms of biological activity, the introduction of fluorine atoms often enhances the binding force between compounds and targets.
2-position cyclopropyl group, its unique cyclic structure endows the molecule with a special spatial conformation, which affects the flexibility and rigidity of the molecule. When interacting with biological macromolecules, it may be able to adapt to specific binding check points, providing unique spatial complementarity.
In summary, the chemical structure of methyl 4- (4 '-fluorophenyl) -2 - (cyclopropyl) -3 -quinoline carboxylic acid ester is composed of quinoline parent nucleus and specific site substituents. The interaction of each part jointly determines the physicochemical and biological activities of this compound.

Methyl-4- (4 '-fluorophenyl) -2- (cyclopropyl) -3-quinoline carboxylic acid ester is an important compound in the field of organic synthesis. Its uses are quite extensive and each has its own strengths.
One of them is often used as a key intermediate in the field of pharmaceutical chemistry. Due to its unique chemical structure, it can provide a cornerstone for the development of new antibacterial and anti-inflammatory drugs. For example, many quinoline compounds have been confirmed to have significant antibacterial activity and can target a variety of pathogenic microorganisms, inhibiting their growth and reproduction. The structure of this compound may be optimized and modified to improve the efficacy of drugs, reduce side effects, and contribute a lot to human health and well-being.
Second, in the field of materials science, it also shows unique potential. Or it can be used to prepare functional materials, such as optoelectronic materials. Because the structure contains specific functional groups, or endows the material with special optical and electrical properties, it can be used in organic Light Emitting Diode (OLED), solar cells and other fields to improve material properties and improve device efficiency and stability.
Third, in agricultural chemistry, it may be developed as a new type of pesticide. In view of its impact on some biological activities, pesticide products with insecticidal, bactericidal, weeding and other effects can be designed and synthesized. In this way, it can help agricultural production, ensure crop yield and quality, and reduce the threat of pests and diseases to agriculture.
In summary, methyl-4- (4 '-fluorophenyl) -2- (cyclopropyl) -3 -quinoline carboxylic acid ester has considerable application prospects in the fields of medicine, materials, agriculture, etc. With the deepening of research, more potential uses may be tapped, which will contribute to the development of various fields.

Methyl 4- (4 '-fluorophenyl) -2- (cyclopropyl) -3-quinolinecarboxylate is an organic compound, and its synthesis method is very important. The synthesis of this compound often follows the classical organic synthesis path, which involves many steps and reactions.
The first step often requires the preparation of key intermediates. A suitable aryl halide and fluorophenyl reagent can be used to construct a fluoroaryl structure through nucleophilic substitution. In this reaction, a suitable base and solvent need to be selected to promote the smooth progress of the reaction. The choice of base, or potassium carbonate, sodium carbonate, etc., and the solvent can be selected from polar aprotic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), which help to improve the reaction efficiency. < Br >
Second step to construct the cyclopropyl moiety. Cyclopropylation reagents can be used to react with the obtained intermediates. Common cyclopropylation reagents such as cyclopropyl halide, in the presence of metal catalysts such as zinc powder and magnesium powder, nucleophilic substitution or addition reactions occur to introduce cyclopropyl into the molecule. This process requires strict control of reaction conditions, such as temperature and reaction time, to ensure that the cyclopropylation reaction occurs accurately and avoid side reactions.
Furthermore, the construction of a quinoline carboxylate skeleton is often achieved through multi-step reactions, or through reaction steps such as condensation and cyclization. For example, an aromatic amine can be used with a suitable carboxylic acid derivative under the action of a condensing agent such as dicyclohexyl carbodiimide (DCC) to undergo a condensation reaction to form an amide bond. Afterwards, under acidic or basic conditions, the cyclization is further formed to form a quinoline structure.
Finally, the resulting product is esterified to obtain the target compound Methyl 4- (4 '-fluorophenyl) -2- (cyclopropyl) -3-quinolinecarboxylate. The esterification reaction is often carried out with alcohol and carboxylic acid catalyzed by acids, such as concentrated sulfuric acid and p-toluenesulfonic acid as catalysts, and heating prompts the reaction to proceed in the direction of ester formation. After the reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to obtain high-purity products. Therefore, the compound can be successfully synthesized by carefully designed and controlled reactions in multiple steps.

Methyl 4- (4 '-fluorophenyl) -2- (cyclopropyl) -3-quinoline carboxylic acid ester is a kind of organic compound. Its physical properties are quite important, which is related to the application and characteristics of this compound.
When it comes to appearance, it usually takes a white to light yellow crystalline powder shape, which is conducive to observation and preliminary identification. Its melting point is about a specific temperature range. According to accurate determination, it is roughly between [specific melting point values]. The stability of the melting point is of great significance for the identification and purification of this compound.
In terms of solubility, it shows a certain solubility in common organic solvents, such as ethanol and acetone, but its solubility in water is not good. This property has a significant impact on chemical synthesis, separation and preparation. Due to differences in dissolution in different solvents, it can help to select the appropriate solvent to achieve the best reaction conditions or separation effect.
Furthermore, the density of this compound is also a key physical property. After determination, its density is about [specific density value], which is indispensable when it comes to mass and volume conversion and mixture-related calculations.
In addition, its stability is acceptable under normal conditions, but it may change in the case of hot topics, open flames or specific chemical reaction conditions. Understanding its stability is crucial during storage and use to ensure that its quality and performance are not damaged.
In summary, the physical properties of methyl 4- (4 '-fluorophenyl) -2- (cyclopropyl) -3-quinoline carboxylic acid esters, such as appearance, melting point, solubility, density and stability, etc., play an important role in guiding their research, production and application in the field of chemistry.

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