Methyl-2-[3-[3-[3-(7-Chloroquinoline-2-Yl) Ethenyl] Phenyl]-3-Oxopropyl] Benzoate

The name of this substance is methyl-2 - [3- [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl] -3-oxopropyl] benzoate. Its chemical structure is composed of multiple parts:
1. Benzoate moiety: With benzoic acid as the parent body, a methyl group forms an ester bond with the carboxyl group of benzoic acid, that is, the -COOCH 🥰 structure, which is one end of the whole molecule.
2. Propyl fragment: "3-oxopropyl" indicates that there is a carbonyl group (C = O) at the 3rd position of the propyl group, that is, -CH _ CH _ C = O - structure.
3. Phenyl series: One end of the propyl group is connected to a phenyl group, which in turn is connected to another phenyl group with a specific substituent, nested in layers.
4. Quinoline fragment: One of the phenyl groups is connected to a 7-chloroquinoline-2-yl vinyl structure. Quinoline is a nitrogen-containing heterocyclic compound with chlorine atom substitution at position 7, and position 2 is connected to the vinyl, that is, -CH = CH- (7-chloroquinoline-2-yl) structure. These structural fragments are connected in sequence and together constitute the complex chemical structure of the compound.

Methyl-2- [3- [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl] -3-oxypropyl] benzoate, which has a wide range of uses. In the field of pharmaceutical development, it may be a key intermediate for the creation of new antimalarial drugs. The harm of malaria has existed in ancient times. Although the prevention and control are effective, the resistance of malaria parasites is gradually emerging, so the demand for new antimalarial drugs is urgent. This compound contains chloroquinoline structure. Chloroquine is a classic antimalarial drug. Its structure can provide the basis for antimalarial activity. By modifying surrounding groups, it may improve drug efficacy and reduce resistance. For example, ancient doctors studied Materia Medica to seek better curative effects with different combinations.
In the field of materials science, this substance may have unique optical and electrical properties. Organic materials constructed with it may emerge in the fields of photoelectric converters and Light Emitting Diodes. For example, ancient skilled craftsmen explore different material characteristics and create exquisite utensils. Today's researchers also hope to use its characteristics to develop high-efficiency photoelectric materials to meet the needs of energy and display technologies.
In the level of scientific research and exploration, it is an important model molecule. Scientists can gain insight into the laws of organic chemistry by studying their reaction mechanisms, structures, and activities. For example, ancient scholars have studied the principles of heaven and earth, laying the foundation for organic synthesis, drug design, and other fields, exploring new directions and exploring unknown possibilities.

Methyl-2 - [3 - [3 - [3 - (7 - chloroquinoline - 2 - yl) vinyl] phenyl] - 3 - oxopropyl] benzoate, the physical properties of this substance are quite important, related to its performance in various application scenarios.
Looking at its shape, it is often in a solid state and has a relatively dense texture. As for color, it is mostly white or off-white, and the appearance is pure and uniform, like the first cut of jade.
When it comes to the melting point, it is about a specific temperature range. This temperature is the key node for it to change from solid to liquid. Accurate determination is essential to grasp the change law of its state. This melting point value can provide a strong basis for the purification and identification of the substance, just like a precise ruler to measure its purity and authenticity.
Furthermore, solubility is also one of its important physical properties. In organic solvents, such as common ethanol, acetone, etc., it shows a certain solubility, but in water, it is not good. This property plays a crucial role in many links such as chemical synthesis, separation and purification, and preparation of preparations. Just as a boat travels in water, the choice of solvent determines whether the substance can travel smoothly in the reaction system or preparation.
In addition, the property of density cannot be ignored. Its density gives the substance the relationship between mass and volume in a specific environment, which affects its distribution and behavior in the mixed system, just like an object in a fluid follows its own density law. These physical properties are intertwined, and together they outline the unique physical "portrait" of methyl-2 - [3- [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl] - 3-oxypropyl] benzoate, which lays the foundation for its application in chemistry, medicine and other fields.

The synthesis of methyl-2 - [3- [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl] -3-oxypropyl] benzoate is a key technique in the field of organic synthesis. The synthesis steps often follow the established chemical principles and methods, and can only be achieved after multiple delicate reactions.
The first step may require the preparation of a key intermediate containing 7-chloroquinoline-2-yl. Or through the halogenation reaction of quinoline derivatives, under specific reaction conditions, such as in a suitable solvent, adding a specific halogenated reagent, carefully controlling the reaction temperature and time, so that the chlorine atom precisely replaces the hydrogen atom at a specific position of quinoline, thereby obtaining 7-chloroquinoline.
Step by step to construct a vinyl-containing structure. The classic Wittig reaction or the Heck reaction can be used. Taking the Wittig reaction as an example, the corresponding phosphorus Yelid reagent is first prepared, and the carbonyl-containing compound is reacted in the presence of a suitable base. After nucleophilic addition and elimination, a carbon-carbon double bond is formed, and the vinyl structure is introduced.
Furthermore, the obtained vinyl-containing intermediate is reacted with a phenyl-containing compound, or by means of Friedel-Crafts reaction, the target substituent is introduced at a specific position in the phenyl ring to construct the structure of [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl].
Subsequently, 3-oxopropyl is introduced at the end of the above structure through a suitable acylation reaction. If an acyl halide or an acid anhydride is used, it is acylated with the corresponding substrate under the action of a suitable catalyst to form the desired 3-oxopropyl structure.
Finally, by esterification, benzoic acid and intermediates containing 3-oxopropyl are reacted in the presence of concentrated sulfuric acid and other catalysts at appropriate temperature and time conditions to achieve the synthesis of methyl-2- [3- [3- [3- (7-chloroquinoline-2-yl) vinyl] phenyl] -3 -oxopropyl] benzoate.
The synthesis process requires fine control of the reaction conditions at each step, including temperature, reaction time, reactant ratio and catalyst dosage, etc., and requires a variety of analytical methods, such as nuclear magnetic resonance, mass spectrometry, etc., to detect the structure and purity of each step of the product in detail to ensure the smooth synthesis path and the accuracy of the product.

This is a rather complex organic compound named "Methyl - 2 - [3 - [3 - [3 - (7 - Chloroquinoline - 2 - Yl) Ethenyl] Phenyl] - 3 - Oxopropyl] Benzoate". There are many things to pay attention to when it comes to the safety of this substance.
First, when chemical synthesis operations, it is necessary to strictly follow the procedures. Due to its complex structure, the synthesis steps may be complex and involve a variety of reagents and conditions. Such as various organic solvents, or flammable and volatile, the operation site should be well ventilated and kept away from fire sources to prevent the risk of fire and explosion. Many reaction reagents or corrosive, such as strong acids, alkalis, etc., need to wear protective equipment when taking them, such as gloves, goggles, etc., beware of contact with skin and eyes. If you accidentally contact, you should immediately rinse with a lot of water and seek medical attention in time.
Second, storage should not be underestimated. According to its physical and chemical properties, choose a suitable environment. If you are sensitive to light and heat, place it in a cool and dark place to prevent deterioration. And because it may have a certain chemical activity, it should not be mixed with substances that are contrary to their properties, so as not to cause chemical reactions and cause safety accidents.
Third, the toxicity of this substance is unknown, and you must not smell or taste it at will during operation. After the experiment is completed, the waste should be properly disposed of and should not be discarded at will to prevent pollution of the environment and harm to the ecology. And the whole process of operation should be carried out under the guidance of professionals. In case of abnormal conditions, correct countermeasures should be taken quickly. In this way, the operation safety can be guaranteed to the greatest extent and accidents can be avoided.