Isoquinoline 8 Carboxylic Acid
quinoline thiophene imidazole thiazole

Isoquinoline-8-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    625662

    Name Isoquinoline-8-carboxylic acid
    Molecular Formula C10H7NO2
    Molecular Weight 173.17 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 262 - 264 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka Approximately 3.98
    Chemical Class Heterocyclic carboxylic acid
    Odor Odorless (usually)
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

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    Frequently Asked Questions

    As a leading Isoquinoline-8-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Isoquinoline-8-carboxylic acid?
    Isoquinoline-8-carboxylic acid is one of the organic compounds. It has a wide range of uses and is widely used in the field of medicinal chemistry. Due to its special structure, it can interact with many targets in organisms, so it is often a key intermediate for the creation of new drugs. For example, its structure can be chemically modified to synthesize compounds with specific pharmacological activities, which can be used to fight various diseases, such as inflammation and tumors.
    In materials science, it also has important value. By specific means, it can be integrated into the material system to improve the properties of materials. For example, it can enhance the stability of materials, change their optical properties, etc., so it is suitable for many fields such as photoelectric materials, sensor materials, etc.
    Furthermore, in the field of organic synthesis chemistry, isoquinoline-8-carboxylic acids, as an important starting material or intermediate, can participate in a series of complex organic reactions to construct more complex organic molecular structures, providing assistance for the development of organic synthesis chemistry, enabling scientists to synthesize more organic compounds with unique properties and functions.
    What are the physical properties of Isoquinoline-8-carboxylic acid?
    Isoquinoline-8-carboxylic acid is one of the organic compounds. It has specific physical properties, which I will describe in detail.
    Looking at its properties, under normal temperature and pressure, it is mostly in a solid state, but the specific morphology varies depending on the preparation and purity, either in a crystalline state or in the shape of a powder. The melting point of this compound is quite critical, and the melting point is often an important indicator for identification and characterization. After investigation, the melting point of isoquinoline-8-carboxylic acid is about [specific melting point value]. At this temperature, it gradually melts from a solid state to a liquid state. This phase transition process has a profound impact on its application under specific conditions.
    Solubility is also an important physical property. In common organic solvents, such as ethanol, dichloromethane, etc., isoquinoline-8-carboxylic acid exhibits a certain solubility. In ethanol, with the increase of temperature, the solubility increases gradually. Due to the increase in temperature, the thermal movement of molecules intensifies, and the interaction between solute and solvent molecules is enhanced. In water, its solubility is relatively limited because of its molecular structure. Although carboxyl groups can form hydrogen bonds with water, the hydrophobicity of the isoquinoline ring has a significant impact, resulting in a low degree of solubility in water.
    In addition, the density of isoquinoline-8-carboxylic acid cannot be ignored. Its density [specific density value], this value is related to its volume and quality in the mixed system. In chemical production and related experimental operations, accurate knowledge of density can accurately control the amount of material and the reaction process.
    In addition, its appearance and color also have characteristics. Pure isoquinoline-8-carboxylic acid, often white to light yellow, if it contains impurities, the color may change, which can be used as a preliminary basis for judging its purity.
    To sum up, the physical properties of isoquinoline-8-carboxylic acids, such as melting point, solubility, density and appearance, are of crucial significance in their research, production and application fields.
    Is Isoquinoline-8-carboxylic acid chemically stable?
    The chemical properties of isoquinoline-8-carboxylic acid are relatively stable. Looking at its structure, the mother nucleus of isoquinoline endows it with certain aromatic properties and conjugated systems, and the existence of carboxyl groups makes it both acidic.
    From the perspective of reactivity, carboxyl groups can undergo many common reactions, such as neutralization with bases to form corresponding carboxylic salts, which are relatively smooth and easy to control. It can also be esterified with alcohols under appropriate conditions. Although this process requires specific catalysts and reaction conditions, the reaction path is relatively clear and the product is relatively stable.
    The isoquinoline ring part, due to the conjugate structure, the electron cloud distribution is relatively uniform, and it is generally not easy to be attacked by active species such as free radicals. However, under extreme conditions such as specific strong oxidizing agents or high temperature and high pressure, its structure may change, but such situations rarely occur in conventional experiments or application scenarios.
    Furthermore, due to its structural characteristics, it has a certain solubility in common organic solvents, which also helps it participate in various homogeneous reactions. During the reaction process, its structural framework can be maintained relatively stable and will not be easily decomposed or rearranged. Therefore, overall, the chemical properties of isoquinoline-8-carboxylic acids are relatively stable, and they can maintain their own structures and properties relatively constant in many chemical reactions and application scenarios.
    What are the synthetic methods of Isoquinoline-8-carboxylic acid?
    The synthesis method of isoquinoline-8-carboxylic acid has been known in ancient times, and the methods are diverse and exquisite.
    First, it can be prepared by the corresponding nitrogen-containing heterocyclic compound through multi-step reaction. First, take a nitrogen-containing heterocyclic parent, whose structure needs to be in line with the skeleton of isoquinoline-8-carboxylic acid. Substitution reaction is carried out with suitable reagents under specific reaction conditions. During the reaction, the choice of temperature and solvent is very critical. If the temperature is too high or too low, it may cause changes in the reaction rate or product selectivity. The solvent used needs to be well miscible with the reactants and reagents without adverse effects on the reaction. After this substitution reaction, the necessary functional groups are introduced to lay the foundation for the subsequent construction of carboxyl groups. < Br >
    Then, through the oxidation reaction, the specific functional group is converted into a carboxyl group. In this oxidation step, the oxidizing agent needs to be carefully selected. Different oxidizing agents have different oxidizing abilities, which may lead to different reaction paths and product purity. If a mild oxidizing agent is selected, the reaction can be precisely controlled to avoid excessive oxidation; if a strong oxidizing agent is used, the reaction may be more violent, and the reaction conditions need to be strictly controlled.
    Second, the method of cyclization reaction can also be used. Select a suitable chain compound, whose structure contains an active check point that can occur cyclization. Under the action of the catalyst, it promotes the cyclization of the molecule to form the basic skeleton of isoquinoline. In this process, the type and dosage of catalysts have a great influence on the efficiency and selectivity of the cyclization reaction. Some metal catalysts can effectively catalyze specific cyclization reactions and improve the yield of the target product.
    After the cyclization is completed, the obtained product is modified to introduce carboxyl groups. The reaction of introducing carboxyl groups also needs to select the appropriate reaction path and reagent according to the structural characteristics of the product to ensure that the carboxyl group can be accurately introduced into the target position without affecting the structure and properties of other functional groups in the molecule.
    These two are common synthesis methods of isoquinoline-8-carboxylic acids. However, the beauty of synthesis lies in the details, and the experimenter needs to study carefully to obtain high-purity products.
    What is the price of Isoquinoline-8-carboxylic acid in the market?
    In today's world, it is not easy to know the price of isoquinoline-8-carboxylic acid in the market. Although "Tiangong Kaiwu" is a strange book, when it was written, the chemical had not yet been published, so it is difficult to find a price solution based on it.
    Today's chemical prices are often influenced by many factors. One is the cost of raw materials. For the production of isoquinoline-8-carboxylic acid, the amount and price of raw materials required have a great impact on its selling price. If raw materials are scarce and expensive, the price of the finished product will be high; conversely, if raw materials are readily available and cheap, the price is expected to decrease.
    The second is the production process. If the production process is complicated, many steps and high-end equipment are required, and the technical requirements are strict, a lot of manpower and material resources are required, which will increase the production cost and cause the market price to rise.
    The third is related to the supply and demand of the market. If the market has strong demand for isoquinoline-8-carboxylic acid, but the supply is limited, the merchant may raise the price due to the shortage of supply; on the contrary, if the supply exceeds the demand, the merchant will sell the goods and may reduce the price.
    The fourth is the policy regulations and environmental protection requirements. The production process needs to comply with relevant regulations. If the environmental protection standards are improved, the enterprise will increase the investment in environmental protection facilities and treatment in order to meet the requirements, which will also increase the cost of the product, thus affecting the price.
    To determine the exact price, please consult chemical product suppliers, distributors, or check chemical product trading platforms, market survey reports, etc., to obtain more accurate price information.