Isoquinoline 6 Bromo 1 2 3 4 Tetrahydro
quinoline thiophene imidazole thiazole

isoquinoline, 6-bromo-1,2,3,4-tetrahydro-

    Specifications

    HS Code

    415755

    Chemical Formula C9H10BrN
    Molecular Weight 212.086
    Appearance Solid (predicted)
    Boiling Point 303.3°C at 760 mmHg (predicted)
    Melting Point N/A
    Density 1.441 g/cm³ (predicted)
    Flash Point 137.2°C (predicted)
    Solubility Soluble in organic solvents like dichloromethane, chloroform (predicted)
    Pka N/A
    Vapor Pressure 0.000912 mmHg at 25°C (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading isoquinoline, 6-bromo-1,2,3,4-tetrahydro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 6-bromo-1,2,3,4-tetrahydroisoquinoline?
    The photophysical properties of 6-bromo-1,2,3,4-tetrahydroisoquinoline are one of a series of characteristics exhibited by the action of light. It has specific light characteristics, and when irradiated by light of a specific wave, it can absorb energy to excitation, and return to the base to produce light. The wave and degree of this light, etc., are the phase of the molecule and the surrounding environment. Its absorption light is also specific, and it does not assimilate the co-structure and functional groups of the body, etc., resulting in different waves of light with different absorption capacities, which can be determined by this analysis. In addition, the substance or has a difference in light quality. Under light or actinic reaction, the molecule can be changed, which affects its photophysical properties. This property is important in many fields such as chemical analysis and optical materials, and can help in the research of new optical materials and high-sensitivity analysis methods.
    What are the chemical properties of 6-bromo-1,2,3,4-tetrahydroisoquinoline?
    6-Bromo-1,2,3,4-tetrahydroisoquinoline is an organic compound with multiple chemical properties.
    It is alkaline. Due to its structure, it contains nitrogen atoms. Nitrogen has solitary pairs of electrons and can bind protons. Salts can be formed in acidic environments. Although this compound is not directly described in Tiangong Kaiwu, it is said in ancient Chinese that its alkalinity is similar to many nitrogen-containing organic bases and can combine with acids to form corresponding salts.
    The bromine atom in this compound is active and can undergo nucleophilic substitution reactions. If there are nucleophiles, bromine atoms are easily replaced, such as by hydroxyl groups, amino groups, etc. This is like an ancient substitution reaction, substituting other substances for their positions. The nucleophilic reagent is like the "force of foreign matter", attacking the position of the bromine atom, causing it to be replaced and form a new compound.
    The unsaturated bond of 6-bromo-1,2,3,4-tetrahydroisoquinoline can participate in the addition reaction. If added with hydrogen, under a suitable catalyst, the unsaturated bond can be combined with hydrogen to increase the saturation of the compound, which is similar to absorbing foreign matter to enrich itself. This addition reaction is commonly used in organic synthesis and can change the structure and properties of the compound. Like ancient techniques, through clever operation, the properties of the substance can be changed.
    The aromatic ring part is aromatic and can undergo electrophilic substitution reaction. The electrophilic reagent can attack the aromatic ring and replace the hydrogen atom on the ring. The electron cloud density distribution of the aromatic ring is special, which leads to electrophilic reagents. This reaction is commonly used in the preparation of derivatives with special functional groups. It seems that a delicate method is used to add new parts to the established place to obtain different products.
    What are the main uses of 6-bromo-1,2,3,4-tetrahydroisoquinoline?
    6-Deuterium-1,2,3,4-tetradeuterium isoprene has the following main uses:
    First, it is used in the field of organic synthesis. This substance is different from ordinary isoprene due to the introduction of deuterium atoms. In the synthesis of organic compounds with special structures and properties, deuterated isoprene can be used as a key raw material. For example, when preparing complex organic molecules with specific stability, reactivity or optical properties, its unique structure can bring special chemical selectivity and stereochemical control to the reaction. For example, in the synthesis of certain pharmaceutical intermediates, the presence of deuterium atoms can change the molecular metabolic pathway, improve drug stability and efficacy, so it is often used by organic chemists to design and synthesize novel drug lead compounds.
    The second is in the field of materials science. In the preparation of special performance polymer materials, 6-deuterium-1,2,3,4-tetradeuterium isoprene can be used as a monomer to participate in the polymerization reaction. The obtained polymer materials exhibit physical properties that are completely different from ordinary materials due to deuterium atomic properties, such as better heat resistance, corrosion resistance or mechanical properties. For example, in high-end fields such as aerospace and electronics, where material properties are strictly required, such deuterium-containing polymer materials may meet special environmental needs and open up new directions for the development of materials science.
    Furthermore, it is used as a tracer in chemical research. Due to the similar chemical properties of deuterium and hydrogen but different masses, deuterium atoms in 6-deuterium-1,2,3,4-tetradeuterium isoprene can be used as markers during chemical reactions or substance conversions. By analyzing their distribution and changes in the reaction products, scientists can deeply explore the reaction mechanism, material transport and conversion pathways. For example, in the study of catalytic reaction mechanism, by tracking the reaction process of deuterium-substituted isoprene, the catalyst mode of action and reaction kinetics can be accurately revealed, providing a key basis for optimizing catalytic reactions and developing efficient catalysts.
    What are the synthesis methods of 6-bromo-1,2,3,4-tetrahydroisoquinoline?
    To prepare 6-bromo-1,2,3,4-tetrahydroisoquinoline, there are many synthesis methods, and the following are common ones:
    First, o-bromobenzaldehyde and 1,2-dibromoethane are used as starting materials. First, the corresponding unsaturated intermediate is obtained by condensation of o-bromobenzaldehyde and 1,2-dibromoethane under the action of alkali. Then, the intermediate is hydrogenated and reduced in the presence of suitable catalysts, such as palladium carbon, etc. 6-bromo-1,2,3,4-tetrahydroisoquinoline can be obtained. In this process, the amount of base and reaction temperature should be paid attention to in the condensation reaction to prevent side reactions; during hydrogenation reduction, the activity of the catalyst and the hydrogen pressure are also key factors.
    Second, 2-bromobenzylamine and acrylate are used as raw materials. The two first undergo Michael addition reaction to generate a specific addition product. Then, the product is cyclized in the molecule under acidic or alkaline conditions to form the structure of 6-bromo-1,2,3,4-tetrahydroisoquinoline. In Michael addition, the ratio of reactants and the reaction solvent have a great influence on the reaction process; in the cyclization reaction, the reaction time and temperature need to be precisely controlled according to the selected acid-base conditions to ensure the yield and purity of the target product.
    Third, select suitable halogenated aromatics and nitrogen-containing heterocyclic precursors. Through the coupling reaction catalyzed by transition metals, such as the cross-coupling reaction catalyzed by palladium, the carbon-nitrogen bond is formed, and then the skeleton of 6-bromo-1,2,3,4-tetrahydroisoquinoline is established. In this method, the selection of transition metal catalysts and the design of ligands are crucial, which can significantly affect the selectivity and efficiency of the reaction. At the same time, the anhydrous and anaerobic conditions of the reaction system also need to be strictly maintained to ensure the smooth progress of the reaction.
    What are the precautions for 6-bromo-1,2,3,4-tetrahydroisoquinoline in storage and transportation?
    6-Cyanogen-1,2,3,4-tetrahydroisoquinoline is a dangerous chemical, and there are many points to be paid attention to in storage and transportation.
    When storing, first, it should be placed in a cool and well-ventilated warehouse. Because of its certain chemical activity, high temperature or poor ventilation can easily cause dangerous reactions. Second, it is necessary to keep away from fire and heat sources. This chemical may cause combustion or even explosion in case of open flames and hot topics, so fire and heat sources must be kept away. Third, it should be stored separately from oxidants and food chemicals, and should not be mixed. Because of its active chemical nature, contact with oxidants may cause violent reactions, endangering safety. Fourth, the warehouse needs to be equipped with suitable materials for containing leaks. If there is a leak, it can be collected and treated in time to avoid the spread of pollution.
    When transporting, first of all, the transport vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. In order to prevent accidents during transportation, it can be responded to in time. Secondly, it is best to transport in the morning and evening in summer. The temperature is high in summer, the chemical is more unstable at high temperatures, and the temperature in the morning and evening is relatively low, which can reduce the risk of transportation. Furthermore, during transportation, it is necessary to ensure that the container does not leak, collapse, fall, or damage. If there is a problem with the packaging, it is easy to cause chemical leakage and cause safety accidents. Finally, it is strictly forbidden to mix and mix with oxidants, edible chemicals, etc. To prevent danger caused by interaction during transportation.