Ethyl R 9 10 Difluoro 3 Methyl 7 Oxo 2 3 Dihydro 7h 1 4 Oxazino 2 3 4 Ij Quinoline 6 Carboxylate
quinoline thiophene imidazole thiazole

ETHYL(R)-9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE

Taiy Chemical

    Specifications

    HS Code

    742527

    Chemical Name ETHYL (R)-9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE
    Molecular Formula C17H14F2N2O4
    Molecular Weight 348.30
    Appearance Solid (predicted)
    Melting Point 167 - 169 °C
    Boiling Point 502.5±50.0 °C at 760 mmHg (predicted)
    Density 1.46±0.1 g/cm³ (predicted)
    Logp 2.01 (predicted)
    Solubility Soluble in DMSO, DMF (Slightly), Methanol (Slightly)
    Pka 0.72±0.10 (Predicted)
    Storage Condition 2-8°C

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    Frequently Asked Questions

    As a leading ETHYL(R)-9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of QUINOLINE-6-CARBOXYLATE ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ]?
    (R) -9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H - [1,4] oxazino [2,3,4-ij] quinoline-6-carboxylic acid ethyl ester, this is an organic compound. To clarify its chemical structure, it is necessary to analyze it from the nomenclature.
    "Ethyl ester", showing that it contains ester group-COOCH ² CH, this is the structural characterization of carboxylic acid and ethanol esters. " (R) ", showing that the compound is chiral, and according to the rules of stereochemistry, the specific atomic space of the (R) configuration is arranged in order.
    "9,10-difluoro", indicating that there is a fluorine atom at the 9 and 10 positions of the parent nucleus. "3-methyl", that is, the parent nucleus has methyl-CH at the 3rd position. "7-oxo", refers to the 7 position as carbonyl > C = O. "2,3-dihydro-7H - [1,4] oxazine and [2,3,4-ij] quinoline", revealing that the parent nucleus is composed of [1,4] oxazine and quinoline, and the 2 and 3 positions are dihydrogen states, and the 7 positions have hydrogen atoms. " 6-Carboxylic acid ", indicating that the 6-position is connected with a carboxyl-COOH, which is esterified with ethanol to obtain the overall structure of the compound.
    In summary, the structure of this compound consists of a specific heterocyclic parent nucleus, connected with fluorine, methyl, carbonyl, ester and other groups, and the three-dimensional configuration is (R) type. Each group is arranged at a specific position in the parent nucleus according to the naming rules.
    What is the main use of ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE?
    ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE, the Chinese name is often (R) -9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H- [1,4] oxazino [2,3,4-ij] quinoline-6-carboxylic acid ethyl ester. This substance is mainly used in the field of medicinal chemistry, especially in the development and preparation of antibacterial drugs.
    This substance has a unique structure and is of great value in the exploration of antibacterial pharmacology. In the process of creating antibacterial drugs, chemists investigated its molecular structure and studied the mechanism of its interaction with bacteria. Due to the specific fluorine atoms, methyl groups and heterocyclic parts in its structure, it can be cleverly combined with key targets in bacteria to interfere with the normal physiological activities of bacteria, such as nucleic acid synthesis, protein metabolism and other processes, and then exhibit significant antibacterial activity.
    Many scientific studies have shown that such compounds have the effect of inhibiting a variety of bacteria, including Gram-positive and Gram-negative bacteria. Some antibacterial drugs developed on this basis may be used in clinical practice to deal with infections caused by various bacteria, such as respiratory tract infections, urinary system infections, etc., to treat diseases and seek well-being for patients. Therefore, ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE like a shining star in the field of pharmaceutical antibacterial drugs, leading the way forward in the development of antibacterial drugs.
    What are the physical properties of ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE?
    (R) -9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H- [1,4] oxazino [2,3,4-ij] quinoline-6-carboxylic acid ethyl ester, which has many physical properties. It is an organic compound, at room temperature, or a crystalline solid, with a white color and a certain luster, such as fine particles closely arranged, and the texture is relatively uniform.
    When it comes to the melting point, it is about a specific temperature range. This temperature is the critical value of its transition from solid state to liquid state, which is of great significance for identification and purification. Its boiling point also has a specific value. When it reaches this temperature, the substance changes sharply from liquid state to gaseous state.
    In terms of solubility, it varies in organic solvents. In polar organic solvents, such as ethanol and acetone, there is a certain solubility, because the molecular structure and polar solvent molecules can interact with specific forces to disperse the molecules in the solvent; while in non-polar solvents, such as n-hexane, the solubility is very small, due to the large difference in the forces between the two molecules, it is difficult to miscible with each other.
    In addition, the density of the substance is moderate, similar to the density of common organic compounds. This characteristic needs to be considered in the separation, mixing and design of containers for chemical production. Its appearance and physical state provide an important basis for setting the conditions for its storage, transportation and use.
    What are the synthesis methods of ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE?
    ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE is an organic compound. There are many synthesis methods, each with its own advantages and disadvantages. The selection method should be based on the actual needs and conditions.
    There is a classic synthesis method, and the starting material is easy to obtain. After multiple steps of reaction, the steps are complicated, and the yield may be poor. First, the compound containing quinoline structure is used to react with fluorine-containing reagents under specific conditions to introduce fluorine atoms. This step requires strict control of the reaction temperature and time. Due to the high activity of fluorine atoms, it is easy to cause side reactions. Subsequent methylation reaction, select suitable methylating reagents and bases, optimize the reaction environment, and ensure the precise introduction of methyl groups. After cyclization, the structure of [1,4] oxazinoquinoline is constructed. This step requires the selection of suitable catalysts and solvents to improve the reaction efficiency and selectivity.
    There are also modern synthesis methods, with transition metal catalysis as the core, high efficiency and good selectivity. Transition metal catalysts such as palladium and copper are used to realize the construction of carbon-carbon and carbon-heteroatomic bonds. For example, the coupling reaction catalyzed by palladium can precisely connect different fragments, shorten the reaction step, and improve the yield and purity. However, transition metal catalysts are expensive, and post-treatment may require complicated steps to remove catalyst residues. Cost and environmental protection need to be considered in large-scale production.
    The method of biosynthesis also has potential. The target compound is synthesized under mild conditions by the catalytic activity of microorganisms or enzymes. Biocatalysts have strong specificity, few side reactions, and environmental friendliness. However, the biosynthetic system is complex, and it is necessary to deeply study the metabolic pathways of microorganisms and the catalytic mechanism of enzymes, optimize the culture conditions and reaction parameters, and achieve the ideal synthesis effect.
    Synthesis of ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE, factors such as starting material cost, difficulty of reaction conditions, yield purity requirements, and environmental protection should be comprehensively considered, and the advantages and disadvantages of classical, modern and biosynthetic methods should be weighed. The optimal route should be selected in order to synthesize this compound efficiently and green.
    What is the market outlook for ETHYL (R) -9,10-DIFLUORO-3-METHYL-7-OXO-2, 3-DIHYDRO-7H- [1,4] OXAZINO [2,3,4-IJ] QUINOLINE-6-CARBOXYLATE?
    (R) -9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H- [1,4] oxazino [2,3,4-ij] quinoline-6-carboxylic acid ethyl ester, this is a promising compound, emerging in the field of medicine, especially in the development of antibacterial drugs.
    Looking at its past, although it has not been available for a long time, it has attracted a lot of attention from the medical community. The reason is that such fluoroquinolone derivatives have a unique chemical structure, giving them potential antibacterial activity. Past studies have shown that the introduction of fluorine atoms in the structure can enhance its affinity with bacterial targets and improve antibacterial efficacy. Early experimental data revealed that the compound exhibited growth-inhibiting effects against some drug-resistant bacteria, igniting hope for the development of new antimicrobial drugs.
    As for the present, with the increasingly serious problem of bacterial resistance, the world is in urgent need of new antimicrobial drugs. This compound has become a research hotspot due to its unique structure and potential activity. Many scientific research teams have dedicated themselves to exploring its antimicrobial mechanism and pharmacokinetic properties. Many laboratories are busy conducting in vitro antimicrobial experiments to accurately determine the minimum inhibitory concentration of various pathogens and evaluate the antimicrobial spectrum. At the same time, some teams have started in vivo experiments in animals to investigate its safety and efficacy.
    Looking to the future, if the research continues to advance and many key issues are solved, this compound is expected to become a new generation of antibacterial drugs. If successfully developed, it will provide a new weapon for the treatment of bacterial infectious diseases and alleviate the problem of drug-resistant bacterial infections. However, the road of research and development is full of thorns, such as the optimization of pharmacokinetic properties and long-term toxicity studies. Only by overcoming many obstacles can (R) -9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H- [1,4] oxazino [2,3,4-ij] quinoline-6-carboxylate truly benefit patients.